Physical Sequelae and Depressive Symptoms in Gynecologic Cancer Survivors: Meaning in Life as a Mediator

Simonelli, Laura E.; Fowler, Jeffrey M.; Maxwell, G. Larry; Andersen, Barbara L.

doi:10.1007/s12160-008-9029-8

Cited by 77 publications

(61 citation statements)

References 59 publications

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“…The identification and support of those EC survivors with unmet needs is a key challenge for health care professionals caring for this population [30]. Previous studies have indicated that levels of clinical depression in gynaecologic cancer survivors up to 5 years post-diagnosis are elevated, compared to healthy controls [8,15,31]. However, in the present study, depression was not observed.…”

Section: Discussioncontrasting

confidence: 63%

Quality of life in long-term survivors of early stage endometrial cancer

Dobrzycka¹,

Terlikowski²,

Kulesza-Brończyk³

et al. 2017

Ann Agric Environ Med.

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Introduction. Endometrial cancer (EC) is the most common gynaecological malignancy in developed countries. Effective treatment of the early stage of the disease is achieved by surgery alone. An increasing number of patients with EC become long-term survivors; therefore, the purpose of this study was to investigate the quality-of-life (QOL) of EC survivors. Materials and Method. A total of 328 survivors who had completed cancer treatment more than 3 years ago, and had previously completed questionnaires concerning QOL -European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and depression -Beck Depression Inventory-II (BDI-II). Patients were grouped into those with surgery alone or surgery with adjuvant radiotherapy. Responses were compared with 284 healthy women who were seen for standard gynaecologic screening examinations. Results. According to the presented results, the QOL of women with EC after surgical treatment was equal to that of healthy women in the control group. Treatment with adjuvant radiotherapy influenced the QOL, with the exception of emotional functioning (p=0.028). No statistically significant differences were found in scores on the BDI-II between groups for the cognitive-affective factor, the somatic factor, or the total sum score.Conclusions. The quality of life in EC survivors approximates that of healthy controls after 3 years post-surgical treatment. Patients treated for early stage EC should be informed about the anticipated good prognosis and the low risk of psychosocial and physical long-term effects. Cancer survivors who are treated by surgery and adjuvant radiotherapy may be especially at risk for emotional functioning problems.

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Section: Discussioncontrasting

confidence: 63%

Quality of life in long-term survivors of early stage endometrial cancer

Dobrzycka¹,

Terlikowski²,

Kulesza-Brończyk³

et al. 2017

Ann Agric Environ Med.

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“…BRADY and colleagues (1999) pointed out that patients characterised by high meaningfulness bore the serious physical symptoms of disease easier and were more contented with their quality of life. Other studies pointed out the mediating role of meaningfulness: patients who after a mutilating operation maintained their belief in the meaning of life, showed less emotional problems (JIM & ANDERSEN 2007;SIMONELLI et al 2008).…”

Section: The Relation Of Meaningfulness and Well-being Among Cancer Pmentioning

confidence: 99%

The relation of perceived meaning of life, meaning of illness and anxious-depressive symptoms among cancer patients

Elekes¹

2017

EJMH

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Our research is based on the literature that shows meaningfulness is a correlate of mental health both in the general population and in the case of patients with a serious illness such as cancer. We had two major goals: 1) to identify the meaning-categories patients find in their illness; 2) to test the relationships between perceived meaning of life, meaning of illness and negative indicators of well-being, like automatic thoughts, anxiety, depression in the case of a population of cancer patients from Romania.This study was completed in March-June of 2012. A number of 102 cancer patients, interned in the 'Ion Chiricuta' Oncology Institute in Romania, completed a battery of scales that measured perceived meaning of life (Meaning in Life Questionnaire, Meaning in Life after Cancer), the intensity of automatic thoughts (Automatic Thoughts Questionnaire), anxiety, depression (Hospital Anxiety and Depression Scale), and answered the question whether they found any meaning in their lives.We could identify the following categories of meaning patients found in their illness: character change, greater appreciation of life, change of priorities, spiritual growth, greater appreciation of close relationships, clarification of goals, development of self-knowledge.In accordance with the literature, our results show that perceived meaning of life (measured by MLaC), correlates negatively with automatic thoughts (r = -0.606), anxiety (r = -0.576), and depression (r = -0.542), and these relations are significant (p = 0.000). Patients who found their illness meaningful, found more meaning in their lives as well (t = 3.041, p = 0.003), and they showed lower levels of anxiety and depression, but these correlations are not significant (p = 0.567 and 0.116).Keywords: cancer patients, existential concerns, meaning of life, meaning of illness, anxiety, depression. Im Einklang mit der Literatur zeigen unsere Ergebnisse, dass der wahrgenommene Sinn des Lebens (gemessen mit MLaC) negativ mit automatischen Gedanken (r = -0,606), Angst (r = -0,576) und Depression (r = -0,542) korreliert und diese Relationen signifikant sind (p = 0,000). Patienten, die ihre Krankheit als sinnhaft empfanden, sahen auch in ihrem Leben insgesamt mehr Sinn (t = 3,041, p = 0,003) und hatten weniger Angst und Depressionen, wobei diese Korrelationen nicht signifikant sind (p = 0,567 and 0,116). Das Verhältnis zwischen dem wahrgenommenen Sinn des

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“…Jacobsen et al [39] Interference Jacobsen et al [40] Interference Interference score range=0.92-0.94 Stein et al [21] Interference Interference score=0.95 Andrykowski et al [42] Interference Interference score=0.95 Booth-Jones et al [43] Interference Dahn et al [44] interference Passik and Kirsh [45] Sum of severity, frequency, interference Wilson et al [46] Interference Hartvig et al [47] Mean of severity, one frequency item, interference Hartvig et al [48] Mean of severity, one frequency item, interference Losito et al [50] Interference Monk et al [51] Interference Shun et al [51] Sum of severity, frequency, interference Sum of severity, frequency, interference=0.92 Siegel et al [52] Interference Temel et al [53] Mean of 4 severity items Young and White [54] Interference Cohen and Fried [55] Mean of severity, frequency, interference Interference score range=0.91-0.93; alpha for sum not reported Donovan et al [56] Mean of 4 severity items 4-item severity score range=0.91-0.93 Jacobsen et al [58] Interference Karvinen et al [59] Interference Lai et al [60] Interference Interference score range=0.92-0.96 Shun et al [61] Sum of severity, frequency, interference Sum of severity, frequency, interference range=0.92-0.95 Donovan et al [20] Mean of 3 severity items Mean of average, most, least=0.84 Espie et al [64] Interference Luciani et al [66] Interference Rogers et al [67] Interference Simonelli et al [68] Interference Interference score=0.94 Yang et al [69] Interference combined with 3 other measures to create symptom stress score Interference score=0.93…”

Section: Reliabilitymentioning

confidence: 99%