Physical Properties of Denture Base Resins Potentially Resistant to <i>Candida</i> Adhesion

Dhir, Gunjan; Berzins, David W.; Dhuru, Virendra B.; Periathamby, Antony Raj; Dentino, A.

doi:10.1111/j.1532-849x.2007.00219.x

Cited by 90 publications

(106 citation statements)

References 30 publications

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“…As part of our continuing studies, these phosphated polymers were examined for their physical and mechanical properties and the data were published previously. 21,22 These studies have shown that the incorporation of phosphate into an acrylic resin denture material by monomer substitution did not affect its impact strength, fracture toughness, and resin bonding ability to artificial teeth. 22 They also suggest that physical properties such as water sorption and solubility of the phosphate incorporated polymers could remain acceptable up to the addition of 10%-20% phosphate anions.…”

mentioning

confidence: 98%

“…22 They also suggest that physical properties such as water sorption and solubility of the phosphate incorporated polymers could remain acceptable up to the addition of 10%-20% phosphate anions. 21,22 More comprehensive microbiological, mechanical, and cytotoxicity assessments and the thermal stability of the polymers are in progress to determine the potential in vivo activity and to explore the clinical utility of these materials.…”

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confidence: 99%

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New phosphated poly(methyl methacrylate) polymers for the prevention of denture-induced microbial infection: an in vitro study

Raj¹,

Dentino²

2011

CCIDE

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Purpose: Poly(methyl methacrylate) (PMMA) has been widely used as a denture-base acrylic resin due to its excellent physical and mechanical properties. However, the material is highly prone to microbial fouling that often leads to Candida-associated denture stomatitis. Incorporation of phosphate groups into PMMA could facilitate adsorption of salivary antimicrobials and inhibit microbial adherence on the polymer surface. An in vitro study evaluated PMMA polymers containing varying amounts of phosphate group for their efficacy to inhibit Candida albicans adhesion, adsorb salivary histatin 5, and exhibit candidacidal activity. Methods: Six PMMA polymers containing 0%, 5%, 15%, 10%, 20%, and 25% of phosphate group were synthesized by bead (suspension) polymerization technique using mixtures of methyl methacrylate and methallyl phosphate as monomers. The efficacy of the polymers to inhibit the adherence of C. albicans was examined by using human saliva-coated polymer beads and radio-labeled C. albicans cells, as compared with that of PMMA. The potency of the phosphated PMMA polymers to adsorb histatin 5 was determined by measuring the radioactivity of the adsorbed labeled-peptide on the polymer surface. The candidacidal activity of the histatin 5-adsorbed polymers was assessed by using the fluorescence technique. The percent release of the fluorescent probe calcein from the C. albicans membrane caused by the disruption of the cell membrane was determined. The data were analyzed statistically by one-way ANOVA followed by Scheffé's test (α = 0.05 and n = 6). Results: The presence of $15% phosphate content in PMMA significantly reduced the salivamediated adhesion of C. albicans. Phosphated PMMA polymers showed significantly enhanced adsorption of histatin 5 in a phosphate density-dependent manner. The candidacidal activity of the histatin 5-bound polymers increased significantly with the increase in the phosphate content of the polymer. Conclusion: Phosphated PMMA polymers have the potential to serve as novel denture-base resins, which may reduce C. albicans colonization and prevent denture stomatitis.

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confidence: 98%

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confidence: 99%

New phosphated poly(methyl methacrylate) polymers for the prevention of denture-induced microbial infection: an in vitro study

Raj¹,

Dentino²

2011

CCIDE

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“…26 Akrilik rezinlerde su emilim özelliği PMMA moleküllerinin polaritesi ve su moleküllerinin polimer zincirlerinin arasındaki boşluk alanlarına difüzyonundan etkilenmektedir. 27 Ürethan dimetakrilat monomerleri moleküler yapılarında 2 hidrofilik ürethan grubu bulundururlar. Isı stresi, polimer zincirleri arasındaki mesafeyi arttırarak polimerin su emme özelliğini arttırır.…”

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Akri̇li̇k Rezi̇nler, Yumuşak Astar Materyalleri̇ Ve Doku Düzenleyi̇ci̇leri̇n Çözünürlük Özelli̇kleri̇

Yamaner¹,

Tutal²,

Tuncer³

2015

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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ÖZETGünümüzde Avrupa da ve endüstriyel olarak gelişmekte olan bölgelerde her ne kadar dişsizlik oranı ve diş kayıpları son yıllarda azalıyor ve implant tedavileri daha popüler tedaviler haline geliyor olsa da önü-müzdeki yıllarda da bölümlü veya tam dişsiz hastalar konvansiyonel prostodontik tedaviye ihtiyaç duyacaklardır. Yumuşak astar materyalleri maxillofasi yal ve tam protezlerde tutuculuğu arttırmak, reziduel alveolar kretlerin ilerlemiş rezorbsiyonlarında ve travmatize destek dokuların tedavisinde hastaya konfor sağlamak amacıyla sıklıkla kullanılırlar. Doku düzenleyiciler ise kuvvet dağılımını dengelemek amacıyla protez iç yüzeyine uygulanırlar. Akrilik rezinlerin, yumuşak astar materyallerinin ve doku düzenleyicilerin zaman içeri-sinde yapılarının bozunmasına ve fonksiyonlarının olumsuz etkilenmesine neden olan en önemli özel-liklerden biride çözünürlük özelliğidir. Bu makalede hareketli protezlerin kaide materyali olan akrilik rezinlerin, yumuşak astar materyallerinin ve doku düzenleyicilerin çözünürlük özellikleri incelenmiştir. ABSTRACTIn recent decades, the prevalence of edentulism and the incidence of tooth loss has decreased in Europe and other industrialized regions; furthermore oral implants are becoming more popular. However in coming decades most patients with complete or partial edentulism will continue to receive conventional prosthodontic treatment. Soft denture relining materials are often used in order to gain retention for maxillofacial and complete dentures, to treat the traumatic supporting tissues to provide the comfort for patients and of improved resorbtion of residual alveolar crets. Tissue conditioners are also used for balancing the distribution of the loads. The solubility property is one of the main reason of the the structure of the acrylic resins, soft relining materials and tissue conditioners. In this article the solubility property of the acrylic resins, soft denture relining materials and tissue conditioners are reviewed.

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“…Denture base polymers are susceptible to color change if the cleaning solutions are not correctly used 17 . The surface roughness is of great clinical relevance since it can affect biofilm formation and make it difficult to remove 18 . Therefore, the choice of appropriate methods for denture cleaning is clinically important, when the objective of the procedures is not to cause surface damage of the denture base, and for daily use to prevent microbial adhesion.…”

Section: Introductionmentioning

confidence: 99%

“…Beyond the concern for esthetics, the lack of adequate denture hygiene can cause biofilm accumulation and oral infections such as denture stomatitis 2,3 . It is a common infection characterized by inflammation of oral tissues and colonization of the fitting surface of prostheses by micro-organisms 4 .…”

Section: Introductionmentioning

confidence: 99%

Effect of Denture Cleansers on Flexural Strength, Color Stability and Surface Roughness of Flexible and Microwave cured Acrylic Resin

2017

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Purpose:The aim of the present study was to evaluate the effect of denture cleansers on the flexural strength, color stability and surface roughness of flexible denture base resin as well as micro wave cured denture base resin. Materials and Methods: A total of 144 specimens were fabricated. Seventy two specimens were constructed from each type of resin and were further subdivided into 3 subgroups (n=24) according to their immersion in different types of denture cleansers. Subgroup1: distilled water (control), subgroup 2: 5% sodium hypochlorite and subgroup 3: effervescent alkaline tablets (Corega tabs). The color changes and surface roughness were measured for each subgroup before (baseline) and after immersion in the solutions. The flexural strength was also measured after their immersion. Results: For both groups (flexible denture base resin and microwave cured denture resin groups); control subgroup showed the statistically significant higher flexural strength values, while subgroup treated with Corega Tabs recorded the statistically significant lowest flexural strength values. Regarding the color changes, for both groups (flexible denture base resin and microwave cured denture resin groups); subgroup treated with Corega Tabs recorded statistically significant highest (ΔE) mean values, followed by subgroup treated with sodium hypochlorite then the control subgroup. However, there was a statistically non-significant difference of the Ra values between the tested groups and subgroups. Conclusions: Within the limitations of the study, it was concluded that the tested denture cleansers had no effect on the surface roughness of flexible and microwave cured acrylic resin, however, significantly influenced their flexural strength. Moreover, denture base polymers are susceptible to color change on immersion in Corega Tabs.

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Physical Properties of Denture Base Resins Potentially Resistant to Candida Adhesion

Abstract: Within the limitations of this study, the physical properties of the phosphate denture base resin at 10% should be suitable for denture fabrication based on the properties assessed.

Cited by 90 publications

References 30 publications

New phosphated poly(methyl methacrylate) polymers for the prevention of denture-induced microbial infection: an in vitro study

New phosphated poly(methyl methacrylate) polymers for the prevention of denture-induced microbial infection: an in vitro study

Akri̇li̇k Rezi̇nler, Yumuşak Astar Materyalleri̇ Ve Doku Düzenleyi̇ci̇leri̇n Çözünürlük Özelli̇kleri̇

Effect of Denture Cleansers on Flexural Strength, Color Stability and Surface Roughness of Flexible and Microwave cured Acrylic Resin

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