Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Abstract

Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant extracts in order to create an appropriate environment for wound healing. In this study, we prepared a foam dressing containing E. prostrata leaf extract and gelatin. Chemical composition was verified using Fourier-transform infrared spectroscopy (FTIR) and pore structure was obtained using scanning electron microscopy (SEM). The physical properties of the dressing, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after the dressing was suspended in water. The results revealed that the E. prostrata dressings had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the E. prostrata A and E. prostrata B dressings, respectively). The E. prostrata B dressings showed a higher percentage of weight increase in the first hour and a faster dehydration rate in the first 4 h. Furthermore, the E. prostrata dressings had a slightly acidic environment (5.28 ± 0.02 and 5.38 ± 0.02 for the E. prostrata A and E. prostrata B dressings at 48 h, respectively).

Film dressings from Thai mango seed kernel extracts versus nanocrystalline silver dressings in antibacterial properties

“…Supplementary Material shows all the FTIR spectra of the MSK and gelatin film dressings. Strong absorption bands appear at 1,630–1,634 cm −1 and 1,538–1,545 cm −1 due to the C=O and N-H/C-N bands in the gelatin [ 17 , 18 ]. In addition, a strong absorption band appears at 1,032–1,036 cm −1 due to the C-O-H band in the MSK [ 18 ].…”

“…In addition, the results of chemical characterization found that there were decreased intensities in the absorption band of C=O (1,630-1,634 cm −1 ) and N-H/C-N (1,538–1,545 cm −1 ) in the MSK film dressings due to lower gelatin concentrations [ 17 ]. In contrast, increased intensities in the absorption band of C-O-H (1,032–1,036 cm −1 ) in the MSK film dressings due to higher MSK concentrations [ 18 ].…”