Physical properties and bioactivity of nanocrystalline hydroxyapatite synthesized by a co-precipitation route

Inthong, Suchittra; Tunkasiri, Tawee; Eitssayeam, Sukum; Pengpat, Kamonpan; Rujijanagul, Gobwute

doi:10.1016/j.ceramint.2012.10.129

Cited by 15 publications

(6 citation statements)

References 10 publications

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“…Recently, a variety of methods, such as high-temperature plasma spraying, sol-gel approaches, electrophoretic deposition, pulsed laser deposition, ion-beam deposition and micro-arc oxidation, have been used to modify metal surfaces for dental or orthopedic implants31112131415161718192021. These methods aim to promote implant surface compatibility and to induce bone formation.…”

mentioning

confidence: 99%

Proliferation and osteogenic differentiation of rat BMSCs on a novel Ti/SiC metal matrix nanocomposite modified by friction stir processing

Zhu

Qian

et al. 2016

Sci Rep

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The aims of this study were to fabricate a novel titanium/silicon carbide (Ti/SiC) metal matrix nanocomposite (MMNC) by friction stir processing (FSP) and to investigate its microstructure and mechanical properties. In addition, the adhesion, proliferation and osteogenic differentiation of rat bone marrow stromal cells (BMSCs) on the nanocomposite surface were investigated. The MMNC microstructure was observed by both scanning and transmission electron microscopy. Mechanical properties were characterized by nanoindentation and Vickers hardness testing. Integrin β1 immunofluorescence, cell adhesion, and MTT assays were used to evaluate the effects of the nanocomposite on cell adhesion and proliferation. Osteogenic and angiogenic differentiation were evaluated by alkaline phosphatase (ALP) staining, ALP activity, PCR and osteocalcin immunofluorescence. The observed microstructures and mechanical properties clearly indicated that FSP is a very effective technique for modifying Ti/SiC MMNC to contain uniformly distributed nanoparticles. In the interiors of recrystallized grains, characteristics including twins, fine recrystallized grains, and dislocations formed concurrently. Adhesion, proliferation, and osteogenic and angiogenic differentiation of rat BMSCs were all enhanced on the novel Ti/SiC MMNC surface. In conclusion, nanocomposites modified using FSP technology not only have superior mechanical properties under stress-bearing conditions but also provide improved surface and physicochemical properties for cell attachment and osseointegration.

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mentioning

confidence: 99%

Proliferation and osteogenic differentiation of rat BMSCs on a novel Ti/SiC metal matrix nanocomposite modified by friction stir processing

Zhu

Qian

et al. 2016

Sci Rep

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“…In that work, the particles presented a needle-like shape. Furthermore, platelet particle shape was reported for the HAp powders which prepared by co-precipitation technique [5]. The obtained results suggest that size and morphology of calcium phosphate particles depends on method of preparation.…”

Section: 2mentioning

confidence: 81%

“…HAp and other calcium phosphate compounds can be synthesized from conventional route such as solid-state reaction [4]. It can also be synthesized by other chemical techniques such as co-precipitation [5], and sol-gel synthesis [6]. However, costs of raw materials for these processes are quite high.…”

Section: Introductionmentioning

confidence: 99%

Effects of Calcium Carbonate Synthesized from Cockle Shell on Characteristics of Calcium Phosphate Biphasic

Lertcumfu

Jarupoom

Arkornsakul

et al. 2015

AMM

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Calcium phosphate is a biomaterial which exhibits excellent biocompatibility, bioactivity and biodegradability for bone replacement and other medical applications. In the present work, multiphasic calcium phosphate compounds consisting of hydroxyapatite (HAp) and tri-calcium phosphates (TCP) were prepared by a solid state reaction method. Effects of calcium carbonate (CaCO3: ±3-5 wt%) on the properties of the studied powders were investigated where calcium carbonate powder was synthesized from a natural product (cockle shell). The phase formation and morphology of the powders were characterization by many techniques such as XRD, SEM and dynamic light scattering techniques. The results showed that amount of calcium carbonate additive affected on the properties of the studied samples.

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“…Firstly, HA nanopowder was synthesized from calcium nitrate tetrahydrate solution and di-Ammonium hydrogen phosphate solution by the co-precipitation method. The ammonium hydroxide solution was added in the solution during the co-precipitation route for controlling the pH of the solution at 8 [10]. The solution was mixed and stirred in the atmosphere and room temperature until the chemical reaction complete.…”

Section: Methodsmentioning

confidence: 99%

Influence of Sintering Temperature on Physical and Mechanical Properties of Hydroxyapatite-Calcium Titanate Composite

Inthong

Sweatman

Eitssayeam

et al. 2019

KEM

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This research is concerned with the effect of sintering temperature on physical and mechanical properties. This Hydroxyapatite-calcium titanate (HA-CT) composites were synthesized using conventional route technique. The HA-CT composites were sintered between 1200 up to 1300 °C. The effect of sintering temperature on the physical and mechanical properties of HA-CT composites was discussed. The physical properties were studied in term of densification and apparent porosity. As well as, the mechanical properties were determined in term of Vickers microhardness. The increasing of the sintering temperature increased both of the bulk density and the Vickers microhardness properties. However, the apparent porosity was decreased with increasing sintering temperature. The highest bulk density was found at 0.15 mol.% of CT in HA-CT composites which was sintered at 1300 °C for 3 h. Moreover, the mechanical properties as a function of the sintering temperature and the CT contents were also discussed and compared with other related work.

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Physical properties and bioactivity of nanocrystalline hydroxyapatite synthesized by a co-precipitation route

Cited by 15 publications

References 10 publications

Proliferation and osteogenic differentiation of rat BMSCs on a novel Ti/SiC metal matrix nanocomposite modified by friction stir processing

Proliferation and osteogenic differentiation of rat BMSCs on a novel Ti/SiC metal matrix nanocomposite modified by friction stir processing

Effects of Calcium Carbonate Synthesized from Cockle Shell on Characteristics of Calcium Phosphate Biphasic

Influence of Sintering Temperature on Physical and Mechanical Properties of Hydroxyapatite-Calcium Titanate Composite

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