Physical performance following acute high-risk abdominal surgery: a prospective cohort study

Jønsson, Line Rokkedal; Ingelsrud, Lina Holm; Tengberg, Line Toft; Bandholm, Thomas; Foss, Nicolai Bang; Kristensen, Morten Tange

doi:10.1503/cjs.012616

Cited by 32 publications

(50 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, all orthopedic and geriatric patients, [27,28] and patients undergoing any type of surgery can be assessed with the CAS for early evaluation of mobility status, and for planning of acute and post-acute rehabilitation. Also, Jønsson et al [29] assessed physical performance of patients undergoing acute high-risk abdominal surgery using the CAS. Further, determination of the CAS for long-term mobility level could not be examined, which can be considered another limitation of this study.…”

Section: Discussionmentioning

confidence: 99%

Translation, reliability, agreement and validity of the Turkish version of Cumulated Ambulation Score in patients with hip fracture

Çolak

2020

Jt Dis Relat Surg

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Translation, reliability, agreement and validity of the Turkish version of Cumulated Ambulation Score in patients with hip fracture

Çolak

2020

Jt Dis Relat Surg

View full text Add to dashboard Cite

show abstract

“…Cumulated Ambulation Score (CAS) [ 49 ] will be measured in the postoperative period, as a measurement of day-to-day basic mobility. For acute abdominal surgery a poor CAS is associated with pulmonary complications and low activity in the first postoperative week [ 50 ] and CAS has been shown to be predictive for discharge to a higher level of dependence [ 49 ]. CAS will be compared between groups and investigated as a predictor for poor postoperative outcome independent of patient allocation to control or intervention group.…”

Section: Methodsmentioning

confidence: 99%

Geriatric assessment and intervention in older vulnerable patients undergoing surgery for colorectal cancer: a protocol for a randomised controlled trial (GEPOC trial)

et al. 2021

View full text Add to dashboard Cite

Background The incidence of colorectal cancer (CRC) increases with age. Older patients are a heterogeneous group ranging from fit to frail with various comorbidities. Frail older patients with CRC are at increased risk of negative outcomes and functional decline after cancer surgery compared to younger and fit older patients. Maintenance of independence after treatment is rarely investigated in clinical trials despite older patients value it as high as survival. Comprehensive geriatric assessment (CGA) is an evaluation of an older persons’ medical, psychosocial, and functional capabilities to develop an overall plan for treatment and follow-up. The beneficial effect of CGA is well documented in the fields of medicine and orthopaedic surgery, but evidence is lacking in cancer surgery. We aim to investigate the effect of CGA on physical performance in older frail patients undergoing surgery for CRC. Methods GEPOC is a single centre randomised controlled trial including older patients (≥65 years) undergoing surgical resection for primary CRC. Frail patients (≤14/17 points using the G8 screening tool) will be randomised 1:1 to geriatric intervention and exercise (n = 50) or standard of care along (n = 50) with their standard surgical procedure. Intervention includes preoperative CGA, perioperative geriatric in-ward review and postoperative follow-up. All patients in the intervention group will participate in a pre- and postoperative resistance exercise programme (twice/week, 2 + 12 weeks). Primary endpoint is change in 30-s chair stand test. Assessment of primary endpoint will be performed by physiotherapists blinded to patient allocation. Secondary endpoints: changes in health related quality of life, physical strength and capacity (handgrip strength, gait speed and 6 min walking test), patient perceived quality of recovery, complications to surgery, body composition (Dual-energy X-ray absorptiometry and bioelectric impedance), serum biomarkers, readmission, length of stay and survival. Discussion This ongoing trial will provide valuable knowledge on whether preoperative CGA and postoperative geriatric follow-up and intervention including an exercise program can counteract physical decline and improve quality of life in frail CRC patients undergoing surgery. Trial registration Prospectively registered at Clinicaltrials.gov NCT03719573 (October 2018).

show abstract

“…Functional performance has, in some studies, been indicative of poor postoperative rehabilitation (Kristensen et al 2010;Jønsson et al 2017), and evaluation of physical performance is considered one of the cornerstones in defining frailty (Lytwyn et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Functional performance and 30-day postoperative mortality after emergency laparotomy—a retrospective, multicenter, observational cohort study of 1084 patients

et al. 2020

Self Cite

View full text Add to dashboard Cite

Background: Despite the importance of predicting adverse postoperative outcomes, functional performance status as a proxy for frailty has not been systematically evaluated in emergency abdominal surgery. Our aim was to evaluate if the Eastern Cooperative Oncology Group (ECOG) performance score was independently associated with mortality following high-risk emergency abdominal surgery, in a multicentre, retrospective, observational study of a consecutive cohort. Methods: All patients aged 18 or above undergoing high-risk emergency laparotomy or laparoscopy from four emergency surgical centres in the Capitol Region of Denmark, from January 1 to December 31, 2012, were included. Demographics, preoperative status, ECOG performance score, mortality, and surgical characteristics were registered. The association of frailty with postoperative mortality was evaluated using multiple regression models. Likelihood ratio test was applied for goodness of fit. Results: In total, 1084 patients were included in the cohort; unadjusted 30-day mortality was 20.2%. ECOG performance score was independently associated with 30-day mortality. Odds ratio for mortality was 1.70 (95% CI (1.0, 2.9)) in patients with ECOG performance score of 1, compared with 5.90 (95% CI (1.8, 19.0)) in patients with ECOG performance score of 4 (p < 0.01). Likelihood ratio test suggests improvement in fit of logistic regression modelling of 30-day postoperative mortality when including ECOG performance score as an explanatory variable. Conclusions: This study found ECOG performance score to be independently associated with the postoperative 30-day mortality among patients undergoing high-risk emergency laparotomy. The utility of including functional performance in a preoperative risk assessment model of emergency laparotomy should be evaluated.

show abstract

Physical performance following acute high-risk abdominal surgery: a prospective cohort study

Cited by 32 publications

References 56 publications

Translation, reliability, agreement and validity of the Turkish version of Cumulated Ambulation Score in patients with hip fracture

Translation, reliability, agreement and validity of the Turkish version of Cumulated Ambulation Score in patients with hip fracture

Geriatric assessment and intervention in older vulnerable patients undergoing surgery for colorectal cancer: a protocol for a randomised controlled trial (GEPOC trial)

Functional performance and 30-day postoperative mortality after emergency laparotomy—a retrospective, multicenter, observational cohort study of 1084 patients

Contact Info

Product

Resources

About