Physical performance capacity after pediatric kidney transplant and clinical parameters associated with physical performance capacity

Mäenpää, Heidi; Tainio, Juuso; Arokoski, Jari; Jahnukainen, Timo

doi:10.1007/s00467-022-05758-0

Cited by 3 publications

(1 citation statement)

References 38 publications

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“…We have previously reported delayed motor development in 26.6% of CNF patients during their early childhood. 24 Possible factors affecting early motor development include long-lasting hypoproteinaemia and altered muscle structure with regard to CKD. In the present study, motor development was assessed to be better in the group with a late nephrectomy.…”

Section: Discussionmentioning

confidence: 99%

Late nephrectomy in infants with congenital nephrotic syndrome of the Finnish type

Suihko,

Tainio,

Tuokkola

et al. 2024

Acta Paediatrica

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AimBilateral nephrectomy is commonly performed in patients with congenital nephrotic syndrome of the Finnish type. The optimal timing of nephrectomy is unclear.MethodsGrowth, thromboembolic events, infections, transplant‐related complications and ability to eat were compared between infants with early (Group 1, n = 13) and late (Group 2, n = 10) nephrectomy. ‘Early’ was defined as nephrectomy at 7‐kg body weight followed by peritoneal dialysis and ‘late’ as nephrectomy at ≥10 kg followed by 3–4 weeks of haemodialysis and kidney transplantation. Patients were followed until the end of the first post‐transplant year.ResultsDialysis time was significantly longer in group 1 than in group 2. Late nephrectomy did not increase the risk for thromboembolic events or septicaemia but decreased tube feeding dependency (group 1 69% vs. group 2 20%, p = 0.019). Motor development at transplantation was considered normal in 80% of the infants with late nephrectomy compared to 31% in the early nephrectomy group (p = 0.019); however, the difference between the groups disappeared by the end of the follow‐up.ConclusionInfants with late nephrectomy have comparative outcome but less feeding tube dependency and better motor development during the first post‐transplant months compared to infants with early nephrectomy.

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Section: Discussionmentioning

confidence: 99%

Late nephrectomy in infants with congenital nephrotic syndrome of the Finnish type

Suihko,

Tainio,

Tuokkola

et al. 2024

Acta Paediatrica

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Delayed nephrectomy compared to early nephrectomy is associated with less feeding tube dependency and offers otherwise comparable outcome in infants with congenital nephrotic syndrome

Suihko,

Tainio,

Tuokkola

et al. 2024

Preprint

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Background The only effective treatment for severe forms of congenital nephrotic syndrome is nephrectomy and kidney transplantation (KT). Optimal timing of nephrectomy is unclear. Methods The influence of early (Group 1, n = 13) versus delayed (Group 2, n = 10) nephrectomy on patient outcome was evaluated. The key laboratory results, growth, number of thromboembolic events and infections, KT-related complications, and ability to eat after KT were compared between the two groups. Results Patients in group 1 were significantly younger at nephrectomy compared to group 2 (278 vs. 408 days, p = 0.007) and the dialysis time was significantly (p < 0.001) longer, 261 vs. 36 days, respectively. The occurrence of thromboembolic events or septicemia before KT did not differ between the groups. In group 1, eating difficulties and need for enteral tube feeding were more common than in group 2. Enteral tube feeding dependency at discharge, 3 months, and 6 months post-KT were 100%, 92%, and 69% in group 1 and 90% (p = 0.244), 50% (p = 0.022), and 20% (p = 0.019) in group 2, respectively. Motor development was considered normal before KT and 12 months after the KT in 30.8% and 84.6% of the patients in group 1 and in 80% (p = 0.019) and 90% (p = 0.704) in group 2, respectively. Conclusions Infants with delayed nephrectomy seem to have comparative outcome but less feeding tube dependency and better motor development during the first post-KT months compared to infants with early nephrectomy.

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From designing minimum data set to developing kidney transplantation registry in Iran

Akhlaghi,

Langarizadeh,

Rahimzadeh

et al. 2023

Journal of Family Medicine and Primary Care

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Objective: Currently, population growth and increasing life expectancy are becoming one of the biggest public health challenges in the world, which has increased the prevalence of chronic diseases such as end-stage renal disease and the need for kidney transplantation. The use of a variety of registries has the potential to determine the effectiveness of clinical care and costs and improve the quality of patient care. The aim of this study is to design minimum data set to develop a kidney transplantation registry in Iran to improve the quality of care for people with end-stage renal disease. Methods: The present research is descriptive-applied. The minimum data set was reviewed and evaluated in expert panel meetings. The various elements of the minimum data set were discussed, and specialists in urology, nephrology, health information management, and medical informatics presented their views. Results: The characteristics of the kidney transplantation registry in the form of eight axes of purpose, structure, data sources, minimum data set, classification systems, data processing and reporting, distribution and access to information, and data quality were extracted and finally these characteristics were approved by experts. The relevant tables were validated and were within the acceptable range from the point of view of experts. Conclusion: In developing a kidney transplantation registry in Iran, the necessary requirements and features for designing a web-based registry have been considered. The prototype of this registry in the country will help to collect higher quality data. It is hoped that by developing this registry, a step will be taken to better manage the information on people with end-stage renal disease, provide better services to these patients, and facilitate related research.

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Physical performance capacity after pediatric kidney transplant and clinical parameters associated with physical performance capacity

Cited by 3 publications

References 38 publications

Late nephrectomy in infants with congenital nephrotic syndrome of the Finnish type

Late nephrectomy in infants with congenital nephrotic syndrome of the Finnish type

Delayed nephrectomy compared to early nephrectomy is associated with less feeding tube dependency and offers otherwise comparable outcome in infants with congenital nephrotic syndrome

From designing minimum data set to developing kidney transplantation registry in Iran

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