Physical methods and techniques : NMR spectroscopy

Abstract

This review covers the period 2005-2007, with a handful of leading references to important older reviews. Nuclear Magnetic Resonance spectroscopy continues to evolve, with sensitivity, selectivity, rapid acquisition, and high-throughput automation driving innovation. Solid-state NMR spectroscopy has exploded in importance and has been used to investigate small organic molecules and large biomolecules. A new high-resolution heteronuclear corellation method is described (H2BC) and a 38 year old method is resurrected (DEFT). Novel NMR techniques such as fast acquisition methods, optical detection, detection in mT fields (2 Hz), and MAS MRI of a live mouse are highlighted. I am endebted to the great and the good whose work has been reported here. All credit is theirs; errors, omissions and blame are all mine.

Solid-State NMR Spectroscopy

“…With a field as wide as this one has become, there are multiple special reviews. One may find published reviews on subjects as diverse as applications of solid-state NMR to material science, polymer chemistry, biomolecular solids, and inorganic solids – . In addition, there are always reviews in such series as Specialist Periodical Reports and Progress in Nuclear Magnetic Resonance Spectroscopy that may cover the solid-state techniques.…”