Physical Dosimetry and Spectral Characterization of Neutron Sources for Neutron Capture Therapy

Nigg, David W.

doi:10.1007/978-3-642-31334-9_13

Cited by 3 publications

(2 citation statements)

References 52 publications

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“…Experimental modality and research activities were also performed in (MNRC) [49], RA-6 [88], RA-3 [87], OSTR [83], OSURR [52], PBF [84], RA-1 [86], GTRR [38] and WSU [95]. Table 5 represents the materials used in BSA structure of Americas BNCT facilities.…”

Section: Nrrs For Bnct In Americamentioning

confidence: 99%

Neutron beams implemented at nuclear research reactors for BNCT

2017

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A: This paper presents a survey of neutron beams which were or are in use at 56 Nuclear Research Reactors (NRRs) in order to be used for BNCT, either for treatment or research purposes in aspects of various combinations of materials that were used in their Beam Shaping Assembly (BSA) design, use of fission converters and optimized beam parameters. All our knowledge about BNCT is indebted to researches that have been done in NRRs. The results of about 60 years research in BNCT and also the successes of this method in medical treatment of tumors show that, for the development of BNCT as a routine cancer therapy method, hospital-based neutron sources are needed. Achieving a physical data collection on BNCT neutron beams based on NRRs will be helpful for beam designers in developing a non-reactor based neutron beam. K: Instrumentation for neutron sources; Instrumentation for particle-beam therapy 1Corresponding author.

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Section: Nrrs For Bnct In Americamentioning

confidence: 99%

Neutron beams implemented at nuclear research reactors for BNCT

2017

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“…The detector uses a single photomultiplier, and shows the potential for use of the 6 LiF:ZnS(Ag) scintillator in a simple, fast neutron spectrometer through the capture-gating technique, while maintaining high neutron detection efficiency. These characteristics make it highly suitable for a number of applications in nuclear security, but also for applications in basic research such as antineutrino detection [24,25,26] and medical applications [27,28]. Additionally, we report on the independently characterized optical properties of the 6 LiF:ZnS(Ag) scintillator and its performance within the heterogeneous fast neutron detector.…”

Section: Introductionmentioning

confidence: 99%

Development and operation of a 6LiF:ZnS(Ag)—scintillating plastic capture-gated detector

Wilhelm

Nattress

Jovanovic

2017

Nuclear Instruments and Methods in Physics Research Section A:

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We report on the design, construction, and operation of a capture-gated neutron detector based on a heterogeneous scintillating structure comprising two scintillator types. A flat, 500 μm thick sheet composed of a mixture of lithium-6-fluoride capture agent, 6 LiF, and zinc sulfide phosphor, ZnS(Ag), is wrapped around scintillating polyvinyl toluene (PVT) in a form of cylinder. The 6 LiF:ZnS(Ag) sheet uses an aluminum foil backing as a support for the scintillating material and as an optical reflector, and its optical properties have been characterized independently. The composite scintillator was tested using 252 Cf, DD fusion, 137 Cs, and 60 Co sources. The intrinsic detection efficiency for neutrons from an unmoderated 252 Cf source and rejection of gammas from 137 Cs were measured to be 3.6% and 10 −6 , respectively. A figure of merit for pulse shape discrimination of 4.6 was achieved, and capture-gated spectroscopic analysis is demonstrated.

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Principles, Recent Developmentsand Perspectives in Boron NeutronCapture Therapy (BNCT)

Sauerwein,

Fischer,

Sancey

et al. 2023

Bio-Algorithms and Med-Systems

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For decades, BNCT was seen as an attractive concept and an intellectual challenge with no prospect of widespread clinical application. This situation has changed fundamentally in just a few years with the progress in accelerator technology. Low-energy, high--intensity neutron sources can now be integrated into hospitals and are therefore directly available for patient treatment. A pioneer in this field is the development in Japan, where patients are already being treated in three hospitals, using in-house accelerator-based systems. Furthermore, the costs associated with the BNCT treatment of recurrent tumors in the head and neck area are already covered by the healthcare system. It is time to keep up to date with this technology and work to make it available to patients in high--tech medicine in other countries, especially in Europe and North America. This short article summarizes the main principles of BNCT, outlines some aspects of its history and mentions ongoing projects as well as some hurdles that need to be overcome, as well as the scientific questions that need to be addressed for wider availability of the method.

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Physical Dosimetry and Spectral Characterization of Neutron Sources for Neutron Capture Therapy

Cited by 3 publications

References 52 publications

Neutron beams implemented at nuclear research reactors for BNCT

Neutron beams implemented at nuclear research reactors for BNCT

Development and operation of a 6LiF:ZnS(Ag)—scintillating plastic capture-gated detector

Principles, Recent Developmentsand Perspectives in Boron NeutronCapture Therapy (BNCT)

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