Physical cleaning by means of electric field in the ultrafiltration of a biological solution

Tarazaga, Carlos C.; Campderrós, Mercedes E.; Padilla, Antonio Pérez

doi:10.1016/j.memsci.2005.11.004

Cited by 52 publications

(24 citation statements)

References 12 publications

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“…In addition, conventional cleaning agents have a negative impact on the environment when they are discharged as waste streams after the cleaning process. To overcome these problems, cleaning based on alternative techniques such as ultrasounds, saline solutions or electromagnetic fields are growing in interest in the last years [7,8]. However, only a few papers are related to the cleaning of membranes by means of saline solutions [9].…”

Section: Introductionmentioning

confidence: 99%

Cleaning of ultrafiltration membranes fouled with BSA by means of saline solutions

Corbatón-Báguena

Álvarez-Blanco

Vincent‐Vela

2014

Separation and Purification Technology

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Accepted ManuscriptThis is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. AbstractIn this work, four ultrafiltration (UF) membranes with molecular weight cut-offs (MWCOs) of 5, 15, 30 and 50 kDa, respectively, were fouled with 1 % BSA aqueous solutions and cleaned with different saline solutions. The influence of MWCO, membrane material and operating conditions on the cleaning efficiency was investigated. Saline solutions were able to clean the 5, 15 and 30 kDa membranes, but not the 50 kDa membrane. NaCl, NaNO 3 , NH 4 Cl and KCl were the most effective salts. The cleaning tests demonstrated that the higher the temperature of the saline solution was, the higher the cleaning efficiency was also. In addition, an increase in the crossflow velocity resulted in an increase in the hydraulic cleaning efficiency (HCE). However, there was an optimum value of salt concentration to clean the membrane effectively. Response Surface 2 Methodology was used to investigate the relationship between salt concentration and temperature in the cleaning process.

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Section: Introductionmentioning

confidence: 99%

Cleaning of ultrafiltration membranes fouled with BSA by means of saline solutions

Corbatón-Báguena

Álvarez-Blanco

Vincent‐Vela

2014

Separation and Purification Technology

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“…Brans et al (2004) have described methods to decrease fouling, some of which refer to experimental conditions such as high cross-flow velocity or backpulsing. Other methods consider the use of modules or operational design, such as the use of air slugs, turbulence promoters, vibrating modules, rotating disk and the use of an electric field to remove charged particles from the membrane (Finnigan and Howell, 1990;Lee et al, 1993;Tarazaga et al, 2006a). In general, these procedures imply upscaling difficulties, damage of susceptible compounds, expensive equipment or high power consumption.…”

Section: Introductionmentioning

confidence: 99%

Assessing performance of skim milk ultrafiltration by using technical parameters

Rinaldoni

Tarazaga

Campderrós

et al. 2009

Journal of Food Engineering

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“…In addition, these conventional cleaning agents cause a negative environmental impact when they are discharged as wastewaters after the cleaning step. For all these reasons, new alternative cleaning techniques, including ultrasounds [15], electromagnetic fields [16] and saline solutions [17] have been developed in the recent years to overcome these problems. Regarding the use of saline solutions, previous studies reported the salting-in and salting-out effect of different cations and anions to increase or decrease, respectively, protein solubility at pH values above and below the isoelectric point of the protein [18,19].…”

Section: Introductionmentioning

confidence: 99%

Destabilization and removal of immobilized enzymes adsorbed onto polyethersulfone ultrafiltration membranes by salt solutions

Corbatón-Báguena

Gugliuzza

Cassano

et al. 2015

Journal of Membrane Science

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ElsevierCorbatón Báguena, MJ.; Cassano, A.; Giorno, L. (2015). Destabilization AbstractIn this work the effectiveness of two saline solutions (NaCl and Na 2 SO 4 ) to clean a permanently hydrophilic polyethersulfone (PESH) ultrafiltration (UF) membrane with a molecular weight cut-off (MWCO) of 30 kDa previously fouled with enzymatic solutions 2 was investigated. The influence of protein concentration in the enzymatic solution during the fouling step and the effect of salt type during the cleaning procedure were studied.The protein aggregation was analysed in solution and onto the membrane surface by using several techniques including Dynamic Light Scattering (DLS), Atomic Force Microscopy (AFM) and Infrared Spectroscopy with Attenuated Total Reflectance (ATR-FTIR). In addition, mechanisms that dominate membrane fouling were studied by fitting some mathematical models (Hermia's models adapted to crossflow filtration, a combined model based on the complete blocking and cake formation equations and a resistance-in-series model) to the experimental data.Fouling results showed that the complete blocking/adsorption on membrane surface was the predominant fouling mechanism. Regarding the cleaning results, higher cleaning efficiency and low residual protein concentration was obtained with NaCl solutions for all the feed solutions tested due to the favourable interaction between Cl -and proteins.

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Physical cleaning by means of electric field in the ultrafiltration of a biological solution

Cited by 52 publications

References 12 publications

Cleaning of ultrafiltration membranes fouled with BSA by means of saline solutions

Cleaning of ultrafiltration membranes fouled with BSA by means of saline solutions

Assessing performance of skim milk ultrafiltration by using technical parameters

Destabilization and removal of immobilized enzymes adsorbed onto polyethersulfone ultrafiltration membranes by salt solutions

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