2015
DOI: 10.1590/s1984-82502015000100007
|View full text |Cite
|
Sign up to set email alerts
|

Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract

Abstract: Calendula is used widely in cosmetic formulations that present phenolic compounds in their chemical constitution. The objective of our research was to develop and evaluate the stability of topical formulations containing 5% hydro-ethanolic extract of calendula leaves, including spreadability, and in vitro photo-protective, and antioxidant capacity. To evaluate the stability, we used organoleptic characteristics, pH, and viscosity parameters. Antioxidant capacity was measured by the DPPH (2,2-diphenyl-1-picrylh… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
32
0
8

Year Published

2018
2018
2023
2023

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 64 publications
(44 citation statements)
references
References 15 publications
2
32
0
8
Order By: Relevance
“…The changes in viscosity results are in accordance with previous results. The values varied from 12,000 to 31,000 mPa s. These variations were expected since, normally, viscosity is directly influenced by temperature variations [32]. Sample S1, stored at room temperature in the light, showed an evident degradation of the compounds, as revealed by organoleptic analysis, as well as a decrease in viscosity.…”
Section: F Vesca Based Hydrogel Stability Studiesmentioning
confidence: 79%
See 1 more Smart Citation
“…The changes in viscosity results are in accordance with previous results. The values varied from 12,000 to 31,000 mPa s. These variations were expected since, normally, viscosity is directly influenced by temperature variations [32]. Sample S1, stored at room temperature in the light, showed an evident degradation of the compounds, as revealed by organoleptic analysis, as well as a decrease in viscosity.…”
Section: F Vesca Based Hydrogel Stability Studiesmentioning
confidence: 79%
“…These results, as well as the ones obtained in the organoleptic analysis, where the appearance and color of the formulation changed, strongly suggest that in this sample the properties of the extract were altered. Elevated temperatures can accelerate chemical reactions, altering the activity of the components, viscosity, appearance, color, formulation odor and flavor, and leading to the degradation of phenolic compounds, since these are sensitive to hydrolysis [32].…”
Section: F Vesca Based Hydrogel Stability Studiesmentioning
confidence: 99%
“…Da mesma forma, notou-se que as formulações armazenadas em alta temperatura foram as que mais sofreram alterações em suas viscosidades. Piana et al (2013), Coelho et al (2016), Fialho et al (2017), Deuschle et al (2015) e Deuschle et al (2018) também observaram maiores variações de viscosidade em suas formulações mantidas em temperaturas elevadas.…”
Section: Discussionunclassified
“…Spreadability can be defined as the expansion of a formulation on a surface after a certain period of time, and it is closely linked to applying these formulations at the site of action. Therefore, sunscreens should allow easy spreading on the skin to ensure nominal SPF (Nesseem, 2011;Deuschle et al, 2015). The results are presented in Table XVI, where MD is the mean diameter.…”
Section: Determination Of the Spreadability Of Npb2 Base And Correctimentioning
confidence: 99%