This 4-year prospective study (N = 662) of victims of a fireworks disaster examines the independent predictive value of peritraumatic dissociation for self-reported intrusions, avoidance reactions, and posttraumatic stress disorder (PTSD) symptom severity at both 18-months (T2) and almost 4-years postdisaster (T3). Peritraumatic dissociation was measured 2-3 weeks after the disaster (T1). Hierarchical multiple regression analyses revealed that peritraumatic dissociation was not a strong independent predictor for intrusions and avoidance reactions and PTSD symptom severity at T2 or at T3 above initial intrusions, avoidance reactions, and psychological distress (T1). Results suggest that an early screening procedure for peritraumatic dissociation, which is aimed at identifying disaster victims who are at risk for long-term psychological disturbances can be omitted.B. Christiaanse is now at GGD Nieuwe Waterweg Noord, Rotterdam, The Netherlands.The Enschede Fireworks Disaster Health Study was conducted on behalf of the Dutch Ministry of Health, Welfare and Sports. We thank Sasja Dorresteijn for her contribution to the second and third survey. We thank Rebecca Stellato of the Dutch National Institute for Public Health and the Environment (RIVM) for her contribution to the three surveys. We are grateful for the cooperation of the affected residents who participated in the surveys.