“…This is consistent with a large body of research indicating a high prevalence of psychiatric comorbidity among those with substance abuse problems. 2,18,33 The need for treatment of psychiatric comorbidities is important; female patients with higher levels of psychiatric severity are at increased risk of early dropout, 34 and patients with psychiatric problems have generally poorer treatment outcomes. 35,36 Conditions whose prevalences were not found to be different between cases and controls included cancer of the breast, lung, prostate, or colon, as well as diabetes, renal failure, cerebrovascular diseases, and benign conditions of the prostate.…”