Physical activity, risk of death and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies

Lahart, Ian; Metsios, George S.; Nevill, Alan M.; Carmichael, Amtul R.

doi:10.3109/0284186x.2014.998275

Cited by 444 publications

(326 citation statements)

References 56 publications

Supporting

Mentioning

291

Contrasting

Unclassified

Order By: Relevance

“…In clinical practice, several risk-reduction strategies are being used, ranging from lifestyle changes and chemoprevention to invasive interventions such as prophylactic mastectomy and salpingo-oophorectomy (2)(3)(4)(5)(6). Although these interventions are efficient in reducing cancer risk (6,7), they are associated with substantial side effects (8,9) and can negatively affect the quality of life (10).…”

mentioning

confidence: 99%

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

et al. 2016

View full text Add to dashboard Cite

Background parenchymal enhancement (BPE), and the amount of fibroglandular tissue (FGT) assessed with MRI have been implicated as sensitive imaging biomarkers for breast cancer. The purpose of this study was to quantitatively assess breast parenchymal uptake (BPU) on 18 F-FDG PET/CT as another valuable imaging biomarker and examine its correlation with BPE, FGT, and age. Methods: This study included 129 patients with suspected breast cancer and normal imaging findings in one breast (BI-RADS 1), whose cases were retrospectively analyzed. All patients underwent prone 18 F-FDG PET/CT and 3-T contrast-enhanced MRI of the breast. In all patients, interpreter 1 assessed BPU quantitatively using SUV max . Interpreters 1 and 2 assessed amount of FGT and BPE in the normal contralateral breast by subjective visual estimation, as recommended by BI-RADS. Interpreter 1 reassessed all cases and repeated the BPU measurements. Statistical tests were used to assess correlations between BPU, BPE, FGT, and age, as well as inter-and intrainterpreter agreement. Results: BPU on 18 F-FDG PET/CT varied among patients. The mean BPU SUV max ± SD was 1.57 ± 0.6 for patients with minimal BPE, 1.93 ± 0.6 for mild BPE, 2.42 ± 0.5 for moderate BPE, and 1.45 ± 0.3 for marked BPE. There were significant (P , 0.001) moderate to strong correlations among BPU, BPE, and FGT. BPU directly correlated with both BPE and FGT on MRI. Patient age showed a moderate to strong indirect correlation with all 3 imaging-derived tissue biomarkers. The coefficient of variation for quantitative BPU measurements with SUV max was 5.6%, indicating a high reproducibility. Interinterpreter and intrainterpreter agreement for BPE and FGT was almost perfect, with a κ-value of 0.860 and 0.822, respectively. Conclusion: The results of our study demonstrate that BPU varied among patients. BPU directly correlated with both BPE and FGT on MRI, and BPU measurements were highly reproducible. Patient age showed a strong inverse correlation with all 3 imaging-derived tissue biomarkers. These findings indicate that BPU may serve as a sensitive imaging biomarker for breast cancer prediction, prognosis, and risk assessment.

show abstract

mentioning

confidence: 99%

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

et al. 2016

View full text Add to dashboard Cite

show abstract

“…moderate and vigorous activity (World Health Organization [WHO], 2010). Yet, breast cancer survivors who are active after treatment have a lower risk of cancer recurrence, co-morbidities and death from all causes, compared with those who are less active (Lahart et al, 2015;Gonçalves et al, 2014). As reported by Ellis, Butow, Tattersall, Dunn and Houssami (2001) and Gattellari, Voigt, Butow, & Tattersall (2002), being diagnosed with a life-threatening disease such as cancer could affect decision-making, and many patients struggle with complex and difficult treatment decisions.…”

Section: La Identificación De Barreras Como Intervención Para Involucmentioning

confidence: 95%

Barriers Identification as Intervention to Engage Breast Cancer Survivors in Physical Activity

André

Pillaud

Davoust

et al. 2018

Psychosocial Intervention

View full text Add to dashboard Cite

Although scientific evidence supports the role of physical activity (PA) as a safe and effective intervention for improving health-related quality of life (for a review, see Mishra et al., 2012;Irwin, 2009), the majority of cancer survivors do not comply with public health guidelines (Blanchard, Courneya, & Stein, 2008;Lynch et al., 2010), i.e. at least 150 minutes per week of moderate-intensity aerobic PA throughout the week or at least 75 minutes of vigorous-intensity aerobic PA throughout the week, or an equivalent combination of This study was designed to demonstrate the advantage of adding cancer barriers to components of decision-making in the transtheoretical model (TTM). In study 1, questionnaires were completed by 139 breast cancer survivors including decisional balance, cancer-related barriers and stages of readiness. In study 2, efficiency of directly tackling cancer-related barriers through motivational-style conversation was tested in a quasi-experimental design. From study 1, all decisionmaking variables were related to stages of readiness, but cancer-related barriers were the sole predictors of engagement in physical activity. Out of the three groups of study 2, only the group with motivational-style conversation displayed a significant progress for engagement in physical activity. Demonstrating that cancer-related barriers predict stage of change above the effects of the two components of decisional balance provides a validation of positions that put cancer-related barriers as uniquely related to stages of change, and suggests that adding them in decision making variables in TTM's model can provide a genuinely new contribution to the understanding of physical activity adherence. Regarding implication for cancer survivors, these results suggest that in order to stimulate progress in early stages of change, a greater emphasis may be needed on reducing cancer-related barriers. La identificación de barreras como intervención para involucrar a supervivientes de cáncer de mama en actividades físicas R E S U M E NEste estudio fue diseñado para demostrar la ventajas de tener en cuenta las barreras relacionadas con el cáncer en el proceso de toma de decisiones en el modelo transteórico. En el estudio 1 los cuestionarios fueron respondidos por 139 supervivientes de cáncer de mama, en ellos se incluyó el equilibrio decisional, las barreras relacionadas con el cáncer y las etapas de preparación. En el estudio 2 la eficacia de abordar las barreras relacionadas con el cáncer a través de conversaciones de tipo motivacional se puso a prueba con un diseño cuasi-experimental. En el estudio 1 todas las variables de toma de decisiones se relacionaron con las etapas de preparación, pero las barreras relacionadas con el cáncer fueron los únicos predictores de la participación en la actividad física. De los tres grupos del estudio 2, sólo el grupo con conversación de tipo motivacional mostró un progreso significativo para la participación en la actividad física. Demostrar que las barreras relacionadas con el cáncer pre...

show abstract

“…The results of this investigation show a reduced mortality risk with higher physical fitness for cancer overall and for various types of cancer specifically (Table) [8,[41][42][43][44][45][46][47][48][49][50][51]. Increased PA is associated with lower cancer-related and all-cause mortality rates in cancer survivors, and PA showed a suppressive effect on mortality rate [52][53][54]. The efficacy of PA has been demonstrated with endpoints other than mortality rate.…”

Section: Effects Of Physical Activity For Cancer Survivorsmentioning

confidence: 99%

The impact of physical activity on cancer prevention and survivorship

Yamaga¹,

Yamamoto²,

Keiji³

2017

Phys Med Rehabil Res

View full text Add to dashboard Cite

Physical activity, risk of death and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies

Cited by 444 publications

References 56 publications

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

Barriers Identification as Intervention to Engage Breast Cancer Survivors in Physical Activity

The impact of physical activity on cancer prevention and survivorship

Contact Info

Product

Resources

About

Physical activity, risk of death and recurrence in breast cancer survivors: A systematic review and meta-analysis of epidemiological studies

Cited by 444 publications

References 56 publications

Quantitative Assessment of Breast Parenchymal Uptake on 18F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

Quantitative Assessment of Breast Parenchymal Uptake on 18F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

Barriers Identification as Intervention to Engage Breast Cancer Survivors in Physical Activity

The impact of physical activity on cancer prevention and survivorship

Contact Info

Product

Resources

About

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI

Quantitative Assessment of Breast Parenchymal Uptake on ¹⁸F-FDG PET/CT: Correlation with Age, Background Parenchymal Enhancement, and Amount of Fibroglandular Tissue on MRI