Physical activity is negatively associated with antral follicle count

Effects of environmental, social and surgical factors on ovarian reserve: Implications for age‐relative female fertility

“…Researchers have increasingly focused on the effects of new lifestyle, food intake, and environmental changes on fertility. Both univariate and multivariate analyses in this study showed that intense exercise and sleep quality have significant negative impacts on AFC in women aged 31–36 years, which was similar to a previous study 12 . Excessive exercise may lower female fertility by reducing ovulation, damaging endometrial development, and inducing amenorrhea 22 .…”

“…In our previous study, we preliminarily analyzed the risk factors for female fertility in 794 women aged under 37 years and found that adnexal surgery, which may disturb the blood supply of female ovaries and impair the normal microenvironment of antral follicle development, was associated with decreased AFC and AMH levels. We found no associations among intense exercise and AFC, body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) and AMH levels, which was not consistent with previous studies 10,12 . The present study analyzed the risk factors affecting female fertility with an expanded sample size and with more age groups.…”

“…Factors affecting female fertility include age, female reproductive function status, genetic factors, and ovarian function. However, there is a relative lack of evaluation of specific factors affecting fertility in women of different ages, especially young women 5,12 . In this study, risk factors for ovarian reserve were analyzed in three age groups of women, matched for optimal age, suboptimal age, and advanced age.…”

“…Both univariate and multivariate analyses in this study showed that intense exercise and sleep quality have significant negative impacts on AFC in women aged 31–36 years, which was similar to a previous study. 12 Excessive exercise may lower female fertility by reducing ovulation, damaging endometrial development, and inducing amenorrhea. 22 Circadian dysrhythmia may interfere with fertility by altering the secretion of reproductive hormones, impairing reproductive outcomes and insulin resistance, and/or increasing inflammation.…”

“…We found no associations among intense exercise and AFC, body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) and AMH levels, which was not consistent with previous studies. 10 , 12 The present study analyzed the risk factors affecting female fertility with an expanded sample size and with more age groups. This work will provide more reliable evidence for female fertility protection for different female age populations.…”