Physical activity in COPD patients: patterns and bouts

Donaire-González, David; Gimeno‐Santos, Elena; Balcells, Eva; Rodríguez, Diego A.; Farrero, Eva; Batlle, Jordi de; Benet, Marta; Ferrer, Antoni; Barberà, Joan Albert; Gea, Joaquim; Rodríguez-Roisín, Robert; Antó, Josep M.; Garcia‐Aymerich, Judith

doi:10.1183/09031936.00101512

Cited by 94 publications

(81 citation statements)

References 32 publications

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“…We think that this result confirms the results of previous studies (32,33). In another study, a moderate to weak relationship was found between daily physical activity and exercise capacity in patients with COPD (34).…”

Section: Total Oxidant Statussupporting

confidence: 82%

Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD

Genç¹,

Üçok²,

Şener³

et al. 2014

Turk J Med Sci

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IntroductionChronic obstructive pulmonary disease (COPD), one of the most common chronic diseases, is a major cause of morbidity. Oxidative stress is a situation of imbalance between free radicals and antioxidants in favor of the oxidants (1). Today, habitual smoking is the most significant threat to the world's population (2). The development of COPD is mainly associated with tobacco or biomass smoke-induced oxidative stress. Smokers are exposed to thousands of reactive chemicals and trillions of radicals and particles with every cigarette; thus, the molecular reactive oxygen, activity of radicals, and nitrogen species can, over time, lead to a number of detrimental changes in the lungs (3). Oxidative stress is thought to play a central role in the pathogenesis of COPD.Maximal aerobic capacity (VO 2 max) is considered the gold standard for evaluating cardiorespiratory fitness (physical functional capacity) (4). Daily physical activity is the actual level of physical performance that one adopts in daily living. It is not synonymous with physical functional capacity, which can be defined as the maximal performance potential of an individual (5). Aerobic exercise limitation is a common and disturbing manifestation of COPD and is often caused by multiple interrelated physiologic and anatomic disturbances (6). Nevertheless, a hypothesis was proposed that individuals with higher current aerobic function will have greater antioxidant and metabolic capacities to deal with the stresses associated with life, including environmental stresses such as chronic cigarette smoke exposure (3).Patients with COPD show high prevalences of cardiovascular diseases and metabolic syndrome (7,8). Obesity and COPD are common and disabling chronic health conditions. A relationship between obesity and COPD is increasingly recognized, although the nature of this association remains unknown (9). Uygur et al. also found that body fat percentage and total body fat were negatively correlated at a strong level with aerobic capacity Background/aim: To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, in patients with mild to moderate chronic obstructive pulmonary disease (COPD) versus healthy controls. Materials and methods:The study included 30 male patients newly diagnosed with COPD and 30 body mass index-matched, nonsmoker male controls. Maximal aerobic capacity, daily physical activity, total oxidant and antioxidant status, pulmonary function tests, body composition, and anthropometric parameters were measured.Results: Maximal aerobic capacity and total antioxidant values were lower in patients with COPD compared to the controls. The total oxidant value, body fat percentage, and waist/hip ratio were higher in patients with COPD than in the healthy controls. There was a moderately negative correlation between the total oxidant value and the maximal aerobic capacity, while there was a moderatel...

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Section: Total Oxidant Statussupporting

confidence: 82%

Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD

Genç¹,

Üçok²,

Şener³

et al. 2014

Turk J Med Sci

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“…DONAIRE-GONZALEZ et al [58] showed that people with COPD across a wide range of disease severity engage in physical activity bouts of moderate-to-vigorous intensities. People with severe and very severe COPD perform their daily activities in fewer and shorter bouts than those with mild or moderate disease [58]. Therefore, a meaningful focus of rehabilitation programmes could be to increase the frequency of bouts of physical activity rather than prolonging the duration of such bouts.…”

Section: Increasing Physical Activitymentioning

confidence: 99%

The importance of components of pulmonary rehabilitation, other than exercise training, in COPD

Hill¹,

Vogiatzis²,

Burtin³

2013

European Respiratory Review

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Comprehensive pulmonary rehabilitation is an important component in the clinical management of people with chronic obstructive pulmonary disease (COPD). Although supervised exercise training is considered the cornerstone of effective pulmonary rehabilitation, there are many other components that should be considered to manage the impairments and symptom burden, as well as the psychosocial and lifestyle changes imposed by COPD. These include approaches designed to: 1) facilitate smoking cessation; 2) optimise pharmacotherapy; 3) assist with early identification and treatment of acute exacerbations; 4) manage acute dyspnoea; 5) increase physical activity; 6) improve body composition; 7) promote mental health; 8) facilitate advance care planning; and 9) establish social support networks. This article will describe these approaches, which may be incorporated within pulmonary rehabilitation, to optimise effective chronic disease self-management. @ERSpublications This paper describes several components of comprehensive pulmonary rehabilitation, other than simply exercise training http://ow.ly/mMNRp Pulmonary rehabilitation for chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease (COPD) is characterised by persistent airflow limitation due to chronic inflammation within the airways and lung in response to noxious particles or gases [1]. People with this condition are limited by dyspnoea and have impaired exercise capacity and health-related quality of life [1]. The prevalence of COPD amongst adults aged o40 years is ,10% [2], and increases to 21% in those with a significant smoking history who are visiting their family physician for any reason [3]. The natural course of COPD is punctuated with episodes of acute worsening, known as exacerbations, which contribute

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“…Patients were invited to participate in a second visit for follow-up assessment 18-24 months later, while clinically stable. In this second visit, a sample of 177 patients, representative of the PAC-COPD cohort [11], accepted the monitoring of their physical activity with an accelerometer (see later). All patients were followed-up until December 31, 2010 or date of death, whichever came first (median 2.6 years).…”

Section: Study Design Participants and Ethicsmentioning

confidence: 99%

“…On average, they wore the accelerometer for 6 days and recorded a mean 95% of daytime hours (13.5 h of a maximum 14 h) [11]. The quantity of physical activity was assessed using 1) the number of steps per day; 2) the number of days per week that the patient could be considered physically active, operationally defined by ⩾5000 steps per day [12]; and 3) time (minutes) per day spent in physical activity (defined as any minute with ⩾1.5 metabolic equivalent tasks (METs)).…”

Section: Measurementsmentioning

confidence: 99%

Benefits of physical activity on COPD hospitalisation depend on intensity

et al. 2015

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The present study aims to disentangle the independent effects of the quantity and the intensity of physical activity on the risk reduction of chronic obstructive pulmonary disease (COPD) hospitalisations.177 patients from the Phenotype Characterization and Course of COPD (PAC-COPD) cohort (mean±SD age 71±8 years, forced expiratory volume in 1 s 52±16% predicted) wore the SenseWear Pro 2 Armband accelerometer (BodyMedia, Pittsburgh, PA, USA) for eight consecutive days, providing data on quantity (steps per day, physically active days and daily active time) and intensity (average metabolic equivalent tasks) of physical activity. Information on COPD hospitalisations during follow-up (2.5±0.8 years) was obtained from validated centralised datasets.During follow-up 67 (38%) patients were hospitalised. There was an interaction between quantity and intensity of physical activity in their effects on COPD hospitalisation risk. After adjusting for potential confounders in the Cox regression model, the risk of COPD hospitalisation was reduced by 20% (hazard ratio (HR) 0.79, 95% CI 0.67-0.93; p=0.005) for every additional 1000 daily steps at low average intensity. A greater quantity of daily steps at high average intensity did not influence the risk of COPD hospitalisations (HR 1.01, p=0.919). Similar results were found for the other measures of quantity of physical activity.Greater quantity of low-intensity physical activity reduces the risk of COPD hospitalisation, but highintensity physical activity does not produce any risk reduction. @ERSpublications Greater quantity of low-intensity physical activity reduces the risk of COPD hospitalisation

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Physical activity in COPD patients: patterns and bouts

Cited by 94 publications

References 32 publications

Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD

Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD

The importance of components of pulmonary rehabilitation, other than exercise training, in COPD

Benefits of physical activity on COPD hospitalisation depend on intensity

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