Physical activity at work and duodenal ulcer risk.

Katschinski, B. D.; Logan, Richard F.; Edmond, M.; Langman, M. J. S.

doi:10.1136/gut.32.9.983

Cited by 17 publications

(9 citation statements)

References 4 publications

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“…Psychologic stress is likely to be important in traditional peptic ulcers, whether related to H pylori or NSAIDs. This effect is likely related to an increase in acid secretion, which enhances the aggressive factors in someone predisposed to peptic ulcer or exacerbates preexisting peptic ulcer by increasing the duodenal acid load [71][72][73].…”

Section: • Master the Hanging Comparative (''Better'' But Better Thamentioning

confidence: 99%

Pathogenesis and therapy of gastric and duodenal ulcer disease

Shiotani

Graham

2002

Medical Clinics of North America

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Section: • Master the Hanging Comparative (''Better'' But Better Thamentioning

confidence: 99%

Pathogenesis and therapy of gastric and duodenal ulcer disease

Shiotani

Graham

2002

Medical Clinics of North America

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“…The most recent analysis [45] found that even after adjusting for the covariates of age, smoking habits and social class, the risk of a recent diagnosis of duodenal ulcer was 1.3 for those who were engaged in moderate physical work, and 3.6 for individuals with a high level of occupational activity.…”

Section: Occupational Activitymentioning

confidence: 96%

Peptic Ulcer and Exercise

Shephard

2016

Sports Med

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Relationships between peptic ulcer and physical activity have as yet received little attention. The prevalence of ulceration is high in racehorses and sled dogs, particularly during periods of competition. In humans, some occupational comparisons show an increased risk among manual workers, but it remains difficult to separate effects of work-related activity from social class and attendant influences of smoking, excessive alcohol consumption, shift work, and other stressors. Two studies of leisure activity point to some benefit from moderate physical activity, one finding a reduced risk of gastric ulcers and the other finding no effect on gastric ulcers but a reduced risk of duodenal ulcers in men only. Moderate physical activity could have a favorable impact on a number of risk factors for peptic ulceration. It could reduce gastric secretions and enhance immune function, with the latter reducing the risk of Helicobacter pylori infection. Moderate activity might also reduce anxiety and encourage the adoption of a healthy lifestyle, with avoidance of smoking and an excessive consumption of alcohol. However, prolonged endurance exercise seems likely to have a negative impact, suppressing immune function, reducing mucosal blood flow, and calling for frequent administration of non-steroidal anti-inflammatory drugs (NSAIDs). As with other aspects of exercise medicine, there may be a J-shaped relationship between dose and response. Limited human observations suggest a favourable response to bouts of moderate leisure activity but little benefit from heavy occupational activity and, in some animal studies, negative effects at high volumes and intensities of exercise. Further research is recommended to confirm the nature of this relationship, clarify the location of any nadir of risk for various classes of individual, and to explore mechanisms and antidotes.

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“…The recurrence rate of gastric consumed alcohol and used NSAIDS. Katschinski et al [20] conducted study in 76 recently diagnosed ulcer patients. It was seen that the risk of physically active work was associated with duodenal ulcer, with relative risk for moderate-and high-activity compared with sedentary work being 1.3 (0.6-30) and 3.6 (1.…”

Section: Vol 3 | Issue 1 | Jan-mar 2012 Chronicles Of Young Scientistsmentioning

confidence: 98%