Physical activity assessment in children and adolescents with juvenile idiopathic arthritis compared with controls

Fazaa, A.; Sellami, Mokhtar; Ouenniche, K.; Miladi, S.; Kassab, S.; Chékili, S.; Abdelghani, K. Ben; Laatar, A.

doi:10.1016/j.arcped.2020.10.008

Cited by 7 publications

(5 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Houghton et al 41 demonstrated the safety of a 6-month exercise program that included jumping, handgrip exercises, resistance training, and group exercises for patients with JIA to improve bone strength and muscle power. Fazaa et al 42 reported that patients with JIA were less active than healthy peers and had lower physical activity than recommended. Deconditioning secondary to active arthritis can cause a rapid decrease in bone mass.…”

Section: Discussionmentioning

confidence: 99%

Bone Mineral Density and Serum 25OHD in Children and Adolescents With Juvenile Idiopathic Arthritis

Charuvanij

Malakorn

Densupsoontorn

et al. 2022

Clin Pediatr (Phila)

View full text Add to dashboard Cite

Low bone mass is one of the complications of juvenile idiopathic arthritis (JIA). However, a study focusing on the low bone mass in children and adolescents with JIA in Southeast Asian countries is limited. This study aimed to evaluate the bone mineral density (BMD) of Thai patients with JIA and identify factors correlated with BMD. A cross-sectional study was conducted at a tertiary-care center. The BMD of the lumbar spines (BMDLS) and the total body (BMDTB) were measured by dual-energy X-ray absorptiometry. Thirty-eight patients were enrolled between July 2015 and January 2016. No patient had low BMDLS, and only 2 (5.3%) had low BMDTB. Serum 25-hydroxyvitamin D (25OHD) levels were significantly positively correlated with the BMDTB Z-score (coefficient: 0.047; 95% confidence interval = 0.011-0.082; P = .012). Our study demonstrated a very low prevalence of low bone mass. Optimization of the serum 25OHD level should be encouraged.

show abstract

Section: Discussionmentioning

confidence: 99%

Bone Mineral Density and Serum 25OHD in Children and Adolescents With Juvenile Idiopathic Arthritis

Charuvanij

Malakorn

Densupsoontorn

et al. 2022

Clin Pediatr (Phila)

View full text Add to dashboard Cite

show abstract

“…In healthy children, moderate and vigorous activity leads to increased lean mass and bone mass [ 127 ], and high-impact activity has an anabolic effect on the growing skeleton, particularly in prepubertal children and in early puberty [ 128 ]. JIA patients, instead, have reduced physical activity, due to bone pain, functional limitation, and lifestyle [ 129 ]. Some studies reported reduced muscle strength, reduced muscle CSA measured by pQCT, and significant bone geometry abnormalities in JIA patients.…”

Section: Secondary Osteoporosis In Children With Rheumatic Diseasesmentioning

confidence: 99%

“…They reported that many JIA patients spent the day sitting or sleeping and presented significantly lower levels of physical activity, compared to healthy children. This was mainly associated with the systemic or polyarticular form and with a more sever course of disease [ 129 ]. Pain seems to be the most important barrier to physical activity, as reported by patients and their parents, together with joint stiffness, muscular weakness, joint swelling and deformities, and constitutional symptoms.…”

Section: Therapeutic Interventionsmentioning

confidence: 99%

Bone Health in Children with Rheumatic Disorders: Focus on Molecular Mechanisms, Diagnosis, and Management

Marcello

Donato

d’Angelo

et al. 2022

IJMS

View full text Add to dashboard Cite

Bone is an extremely dynamic and adaptive tissue, whose metabolism and homeostasis is influenced by many different hormonal, mechanical, nutritional, immunological and pharmacological stimuli. Genetic factors significantly affect bone health, through their influence on bone cells function, cartilage quality, calcium and vitamin D homeostasis, sex hormone metabolism and pubertal timing. In addition, optimal nutrition and physical activity contribute to bone mass acquisition in the growing age. All these factors influence the attainment of peak bone mass, a critical determinant of bone health and fracture risk in adulthood. Secondary osteoporosis is an important issue of clinical care in children with acute and chronic diseases. Systemic autoimmune disorders, like juvenile idiopathic arthritis, can affect the skeletal system, causing reduced bone mineral density and high risk of fragility fractures during childhood. In these patients, multiple factors contribute to reduce bone strength, including systemic inflammation with elevated cytokines, reduced physical activity, malabsorption and nutritional deficiency, inadequate daily calcium and vitamin D intake, use of glucocorticoids, poor growth and pubertal delay. In juvenile arthritis, osteoporosis is more prominent at the femoral neck and radius compared to the lumbar spine. Nevertheless, vertebral fractures are an important, often asymptomatic manifestation, especially in glucocorticoid-treated patients. A standardized diagnostic approach to the musculoskeletal system, including prophylaxis, therapy and follow up, is therefore mandatory in at risk children. Here we discuss the molecular mechanisms involved in skeletal homeostasis and the influence of inflammation and chronic disease on bone metabolism.

show abstract

“… 17 , 18 Another factor that might contribute to poor mental health in this population is an inactive lifestyle. 19 – 21 …”

Section: Introductionmentioning

confidence: 99%

“…17,18 Another factor that might contribute to poor mental health in this population is an inactive lifestyle. [19][20][21] To mitigate the negative effects of home confinement, strategies focused on promoting exercise have been suggested. 22 In fact, studies have shown the therapeutic utility of exercise in patients with autoimmune rheumatic diseases, 23,24 and home-based exercise programs have emerged as clinically effective and cost-effective strategies to improve general health across many clinical conditions.…”

Section: Introductionmentioning

confidence: 99%

A home-based exercise program during COVID-19 pandemic: Perceptions and acceptability of juvenile systemic lupus erythematosus and juvenile idiopathic arthritis adolescents.

Astley

Marques

Iraha

et al. 2022

Lupus

View full text Add to dashboard Cite

Objectives To investigate the perceptions and acceptability of a home-based exercise intervention in systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA) adolescent patients during the COVID-19 pandemic, and to explore the effects of the intervention on health-related quality of life (HRQoL), sleep quality, and mental health conditions parameters. Methods This was a randomized controlled trial of a 12-week, home-based exercise training program conducted between October and December 2020. During this period, social distancing measures were in place in Brazil to contain the spread of COVID-19. Adolescent patients diagnosed with JSLE and JIA participated in the study. Health-related qualitative and quantitative data were collected before and after the follow-up. Results 21 JSLE patients and 30 JIA patients were analyzed. Six themes emerged from patients’ feedback: 1) Suitability of the home-based format; 2) Appropriate trainer supervision, 3) Motivators and facilitators for the program; 4) Barriers to the program; 5) Health benefits; 6) Patients’ suggestions to improve the program. Overall, data indicated that the intervention showed good acceptability and elicited improvements in the perceived HRQoL and fatigue in JIA and JSLE patients during the pandemic. However, further quantitative analyses with validated HRQoL, sleep quality, and mental health conditions instruments did not capture these benefits (p>0.05). Conclusion Our main findings based on in-depth qualitative assessments suggest that a home-based exercise training program was suitable and well-accepted by adolescents with JSLE and JIA during the COVID-19 pandemic. Nonetheless, adherence was not high, particularly among JIA patients, suggesting that facilitators and barriers identified in the current study should be explored to improve the quality of new home-based exercise programs implementation, particularly in a future emerging crisis.

show abstract

Physical activity assessment in children and adolescents with juvenile idiopathic arthritis compared with controls

Cited by 7 publications

References 41 publications

Bone Mineral Density and Serum 25OHD in Children and Adolescents With Juvenile Idiopathic Arthritis

Bone Mineral Density and Serum 25OHD in Children and Adolescents With Juvenile Idiopathic Arthritis

Bone Health in Children with Rheumatic Disorders: Focus on Molecular Mechanisms, Diagnosis, and Management

A home-based exercise program during COVID-19 pandemic: Perceptions and acceptability of juvenile systemic lupus erythematosus and juvenile idiopathic arthritis adolescents.

Contact Info

Product

Resources

About