Physical activity and the osteoarthritis of the knee: A Mendelian randomization study
Xilong Ma,
Kai Zhang,
Chao Ma
et al.
Abstract:Previous studies have reported an association between physical activity and the occurrence and progression of knee osteoarthritis (KOA). However, the existing evidence remains limited and of low-quality. This study aimed to examine the causal relationship between different levels of physical activity and KOA. Instrumental variables, represented by single nucleotide polymorphisms (SNPs), were utilized to capture sedentary behavior, appropriate physical exercise, and excessive physical activity. Aggregated stati… Show more
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