Physical Activity and Mortality in Chronic Kidney Disease (NHANES III)

Beddhu, Srinivasan; Baird, Bradley C.; Zitterkoph, Jennifer; Neilson, Jill; Greene, Tom

doi:10.2215/cjn.01970309

Cited by 256 publications

(212 citation statements)

References 20 publications

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“…To our knowledge, this is the first study to report on PA level and CV and all-cause mortality in these patients. This is consistent with earlier findings in dialysis, CKD, and the general population (8,9,31). Furthermore, it shows low levels of PA are positively associated with CVD risk factors in RTRs.…”

Section: Discussionsupporting

confidence: 92%

Low Physical Activity and Risk of Cardiovascular and All-Cause Mortality in Renal Transplant Recipients

Zelle

Corpeleijn

Stolk

et al. 2011

Clinical Journal of the American Society of Nephrology

124

118

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Section: Discussionsupporting

confidence: 92%

Low Physical Activity and Risk of Cardiovascular and All-Cause Mortality in Renal Transplant Recipients

Zelle

Corpeleijn

Stolk

et al. 2011

Clinical Journal of the American Society of Nephrology

124

118

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“…Several factors, including aging, genetic and environmental factors, and Western lifestyle that includes a high calorie diet and sedentary lifestyle, contribute to the increasing prevalence of metabolic syndrome. Low physical activity levels are common in those patients with CKD and are associated with death in the CKD population (33)(34)(35). Although available data support adopting exercise and intentional weight loss in this population, the quality of the available evidence on this topic is suboptimal (36,37).…”

Section: Discussionmentioning

confidence: 99%

Metabolic Syndrome, ESRD, and Death in CKD

Navaneethan

Schold

Kirwan

et al. 2013

Clinical Journal of the American Society of Nephrology

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SummaryBackground and objectives Previous studies reported an association between metabolic syndrome , incident CKD, and proteinuria. This study examined the associations between metabolic syndrome and its components with ESRD and death among those patients with stages 3 and 4 CKD (estimated GFR=15-59 ml/min per 1.73 m 2 ).Design, setting, participants, & measurements Patients with stages 3 and 4 CKD (n=25,868) who had data relating to metabolic syndrome and were followed in our health care system were identified using an electronic medical record-based registry. Cox proportional hazards models and competing risk analyses were used to study the associations between metabolic syndrome, its components (elevated BP, low HDL cholesterol, elevated serum triglycerides, impaired glucose metabolism, and obesity), and all-cause mortality and ESRD while adjusting for demographics, comorbid conditions, use of relevant medications, and renal function.Results Sixty percent of the study population (n=15,605) had metabolic syndrome. In the multivariate-adjusted analysis, presence of metabolic syndrome was associated with an increased risk for ESRD (hazard ratio=1.33, 95% confidence interval=1.08, 1.64) but not death (hazard ratio=1.04, 95% confidence interval=0.97, 1.12) during a mean follow-up of 2.3 years. Among the individual components of metabolic syndrome, impaired glucose metabolism, elevated triglycerides, and hypertension were associated with increased risk for ESRD, whereas low HDL cholesterol and impaired glucose metabolism were associated with higher risk of death.Conclusions Presence of metabolic syndrome is associated with ESRD but not death in patients with stages 3 and 4 CKD.Clin J Am Soc Nephrol 8: 945-952, 2013.

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“…Patients with ESRD are characterized by low levels of physical activity associated with mobility limitations [2]. Furthermore, observational studies have revealed that physical inactivity is linked to increased early mortality in these patients [3]. Individuals with ESRD initially undergo medical treatment but often eventually require dialysis [4,5].…”

Section: Introductionmentioning

confidence: 99%

Effects of listening to Holy Qur’an recitation and physical training on dialysis efficacy, functional capacity, and psychosocial outcomes in elderly patients undergoing haemodialysis

Frih

Mkacher

Bouzguenda

et al. 2017

Libyan Journal of Medicine

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The purpose of this study was to determine whether listening to Holy Qur’an recitation would augment the beneficial effects of physical exercise on physiological and psychological measures in elderly patients undergoing haemodialysis. Fifty-three male haemodialysis patients were randomly assigned to an intervention group (listening to Holy Qur’an recitation in combination with endurance–resistance training, n = 28) or a control group (endurance–resistance training only, n = 25). Functional capacity was assessed using the Timed Up and Go test (TUG) and the Six-Minute Walk Test (6MWT). Psychosocial outcomes were assessed using the Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) and Hospital Anxiety and Depression Scale (HADS). Dialysis adequacy (Kt/V) was calculated for all patients. After intervention, a significant Group × Period interaction effect was observed for all measured parameters (p < 0.05), except for 6MWT performance (p > 0.05). All measured parameters were significantly improved over baseline in both groups, except for Kt/V in the control group (p > 0.05). Moreover, final measurements were significantly higher in the intervention group than in the control group for all measured parameters, except for 6MWT performance and the physical component summary of the SF-36 (p > 0.05). In conclusion, the present study showed that listening to a recitation of the Holy Qur’an in combination with interdialytic endurance–resistance training induced an improvement in physical condition and quality of life and a large reduction in anxiety among patients undergoing haemodialysis.

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Physical Activity and Mortality in Chronic Kidney Disease (NHANES III)

Abstract: Physical inactivity is associated with increased mortality in CKD and non-CKD populations. As in the non-CKD population, increased physical activity might have a survival benefit in the CKD population.

Cited by 256 publications

References 20 publications

Low Physical Activity and Risk of Cardiovascular and All-Cause Mortality in Renal Transplant Recipients

Low Physical Activity and Risk of Cardiovascular and All-Cause Mortality in Renal Transplant Recipients

Metabolic Syndrome, ESRD, and Death in CKD

Effects of listening to Holy Qur’an recitation and physical training on dialysis efficacy, functional capacity, and psychosocial outcomes in elderly patients undergoing haemodialysis

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