Physical Activity and All-cause Mortality in Japan: The Jichi Medical School (JMS) Cohort Study

Hayasaka, Shinya; Shibata, Yosuke; Ishikawa, Shizukiyo; Kayaba, Kazunori; Gotoh, Tadao; Noda, Tatsuya; Murata, Chiyoe; Yamada, Takeshi; Goto, Yasuaki; Nakamura, Yosikazu; Ojima, Toshiyuki

doi:10.2188/jea.je20080043

Cited by 34 publications

(36 citation statements)

References 15 publications

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“…Many studies have examined the association between physical activity and all-cause death 8 – 11 and reported an inverse dose–response relationship between them 8 ; however, some studies have shown a reverse J-shaped, 9 L-shaped, 10 J-shaped, or U-shaped 11 curve. We found that physical activity was associated with a slight inverse dose–response relationship.…”

Section: Discussionmentioning

confidence: 99%

“…5 , 6 Although some research indicates that only vigorous activity reduces the risk of chronic health conditions, 7 this is controversial. Studies have found a dose–response relationship, 8 as well as reverse J-shape, 9 L-shape, 10 J-shape, and U-shape 11 associations, between physical activity and all-cause death. Cancer is now the leading cause of death in South Korea.…”

Section: Introductionmentioning

confidence: 99%

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Physical Activity Level and Risk of Death: The Severance Cohort Study

Mok

Won

Kim

et al. 2012

Journal of Epidemiology

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BackgroundPhysical activity decreases deaths from cardiovascular disease and other causes; however, it is unclear whether physical activity is associated with cancer incidence and death in Asian populations.MethodsData from 59 636 Koreans aged 30 to 93 years were collected using a questionnaire and medical examination at the Severance Hospital Health Promotion Center between 1994 and 2004. Study participants were followed for a mean duration of 10.3 years.ResultsIn the exercising group, the multivariate Cox proportional hazards model showed a lower risk of cancer death (hazard ratio [HR] = 0.72, 95% CI = 0.62–0.85) in men but not in women. Those who exercised, as compared with those who did not, had lower risks of all-cause death (men: HR = 0.68, 95% CI = 0.60–0.76; women: HR = 0.65, 95% CI = 0.53–0.79) and noncancer death (men: 0.63, 0.53–0.75; women: 0.52, 0.39–0.69). Physical activity was inversely associated with risk of noncancer death among men and women.ConclusionsPhysical activity was associated with lower risks of cancer death and noncancer death.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Physical Activity Level and Risk of Death: The Severance Cohort Study

Mok

Won

Kim

et al. 2012

Journal of Epidemiology

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“…We reviewed 9 major prospective cohort studies of the role of physical activity or physical fitness at baseline in all-cause mortality and/or CVD outcomes in Japan ( Table 2) [42][43][44][45][46][47][48][49][50][51] . Total daily physical activity was assessed based on the estimated energy expenditure 52) , estimated walking time, the MET score (estimated by multiplying the intensity of physical activity by the duration of the activity) 53) , and/or the calculated physical activity index 54) .…”

Section: Major Prospective Cohort Studies In Japanmentioning

confidence: 99%

Physical Activity in the Japan Population: Association with Blood Lipid Levels and Effects in Reducing Cardiovascular and All-Cause Mortality

Koba

Tanaka

Maruyama

et al. 2011

JAT

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According to many prospective cohort studies and meta-analyses of those studies, physical inactivity and/or low levels of physical fitness are associated with an elevated risk for the development of metabolic syndrome, type 2 diabetes, hypertension, coronary artery disease (CAD), and stroke, and with an increased risk of cardiovascular disease (CVD) mortality and all-cause mortality. Most of these analyses, however, were conducted on non-Japanese populations in the West. This report summarizes prospective observational and clinical studies in Japan. The annual national nutrition survey has shown a gradual decline in the number of walking steps in both genders and in all age groups over the last 10 years. While exercise habits have been gradually increasing in the elderly, only one-fifth of young and middle-aged people undertake leisure-time physical activity. Prospective cohort studies have shown that increased physical fitness and greater physical activity in either daily life or leisure time are of benefit in preventing all-cause mortality and CVD mortality. The daily number of walking steps is positively associated with HDL cholesterol levels and negatively associated with triglyceride levels. According to a random-effects model meta-analysis of 4 randomized controlled trials comparing supervised aerobic exercise training with non-exercise control in subjects without CAD, exercise resulted in a significant increase in HDL-cholesterol (10.01 mg/dL, 95% CI 5.38 to 14.65, p 0.0001). While this confirms the importance of physical activity in preventing CVD mortality and all-cause mortality, the levels of physical activity are on a declining trend in Japan, particularly among the young.

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“…The design and methods have been reported previously. [18][19][20] Baseline data were obtained during mass screening examinations between April 1992 and July 1995, and were followed up until the end of 2005. A total of 12,490 individuals, including 754 individual CVD survivors, from 12 areas participated.…”

Section: Study Populationmentioning

confidence: 99%

Physical Activity and Risk of Fatal or Non-Fatal Cardiovascular Disease Among CVD Survivors

Shibata

Hayasaka

Yamada

et al. 2011

Circ J

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Background: Although many population-based studies have reported an association between physical activity and cardiovascular disease (CVD) among healthy populations, the association among CVD survivors has been less reported. We examined the relationship between physical activity and CVD risk among survivors. Methods and Results:This was a prospective cohort study of 12,490 Japanese participants, including 754 individual CVD survivors. Between April 1992 and July 1995, a baseline survey was conducted in 12 communities in Japan. The mean follow-up period was 11.9 years, during which time 74 individuals had non-fatal CVD and 51 cases were fatal CVD. Among CVD survivors, analysis was performed after exclusion of participants with a history of cancer and those who died within the first 2 years of follow-up. Physical activity was analyzed in tertiles (low, moderate and heavy), and the hazard ratios (HRs) were calculated for non-fatal or fatal CVD among CVD survivors. After setting the low group as the reference, the HRs for non-fatal CVD in the moderate and heavy groups were 0.61 (95% confidence interval: 0.30-1.24) and 0.50 (0.20-1.25) (P for trend = 0.059), respectively, and the HRs for fatal CVD were 0.75 (0.33-1.69) and 0.18 (0.04-0.83) (P for trend = 0.026), respectively. Conclusions:Physical activity reduced the risk of CVD, both fatal and non-fatal events, among CVD survivors. (Circ J 2011; 75: 1368 - 1372

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Physical Activity and All-cause Mortality in Japan: The Jichi Medical School (JMS) Cohort Study

Cited by 34 publications

References 15 publications

Physical Activity Level and Risk of Death: The Severance Cohort Study

Physical Activity Level and Risk of Death: The Severance Cohort Study

Physical Activity in the Japan Population: Association with Blood Lipid Levels and Effects in Reducing Cardiovascular and All-Cause Mortality

Physical Activity and Risk of Fatal or Non-Fatal Cardiovascular Disease Among CVD Survivors

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