Phylogeny and taxonomy of the family Arthrodermataceae (dermatophytes) using sequence analysis of the ribosomal ITS region

Gräser, Yvonne; Fari, Mustafa El; Vilgalys, Rytas; Kuijpers, A. F. A.; Hoog, G. S. de; Presber, W; Tietz, Hans‐Jürgen

doi:10.1046/j.1365-280x.1999.00203.x

Cited by 49 publications

(66 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…interdigitale and T. mentagrophytes var. mentagrophytes are genotypically distinct as revealed by 28s and ITS DNA sequencing [4, 5]. From DNA sequence analysis, it is clear that neither variety of T. mentagrophytes can be considered as the anamorph of A. benhamiae.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

First Report of <i>Arthroderma benhamiae</i> in Switzerland

Fumeaux

Mock

Ninet³

et al. 2004

Dermatology

View full text Add to dashboard Cite

Background: Dermatophytes are usually identified on the basis of macroscopic characteristics and microscopic examination of the cultures. Identification of dermatophytes often remains difficult or uncertain because there are variations from one isolate to another and overlapping characteristics between species. Objective: To identify dermatophyte species producing numerous microconidia and resembling Trichophyton mentagrophytes by DNA sequence analysis. Methods: The complete ITS1 + 5.6s + ITS2 rDNA region of various dermatophytes isolated in culture was amplified by PCR and sequenced. Results: Nine isolates of a fast-growing dermatophyte species were identified as Arthroderma benhamiae by DNA sequencing. Retrospective investigations revealed that the isolates were from 8 children and 1 adult suffering from inflammatory dermatophytosis. Eight of the 9 patients had had previous contact with rodents, mostly guinea pigs. Conclusion: It is the first time that A. benhamiae is reported in Switzerland. In cases of dermatophytosis attributed to A. benhamiae, a rodent is the most likely cause of infection.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Complications are also caused by drug pretreatment and pleomorphism that alter important morphological characters. However, the identification of dermatophyte species has been improved by using DNA sequence analysis of the 28s rRNA gene and the internal transcribed spacer (ITS) region [4, 5, 6, 7]. …”

Section: Introductionmentioning

confidence: 99%

First Report of <i>Arthroderma benhamiae</i> in Switzerland

Fumeaux

Mock

Ninet³

et al. 2004

Dermatology

View full text Add to dashboard Cite

show abstract

“…Vorrangig ist hier die Entwicklung genetischer Untersuchungen zur Identifizierung von Pilzen zu nennen [1,17,19,20,23,35]. Mittels der Polymerasekettenreaktion können definierte Genabschnitte von Mikroorganismen amplifiziert und vergleichbar gemacht werden.…”

Section: Neue Vergleichsmethodenunclassified

Dermatophytenspezies

Brasch¹

2008

Hautarzt

View full text Add to dashboard Cite

Taxonomy is an artificial system to classify living organisms. For this purpose, different concepts of how to define a species can be used. In recent years, DNA analysis has especially helped to better understand the phylogenetic relations of dermatophytes and thus influenced the distinction of dermatophyte species. In some cases species previously considered separate were made synonymous. It may be necessary to discriminate different varieties within a particular species if this is required by their typical morphologic, physiologic or epidemiological characteristics. Trichophyton eboreum with its perfect state Arthroderma olidum was recently described as a new species. The taxonomic order of dermatophytes must continuously be updated by integrating new findings; at the same time, meaningful and proven criteria should be retained.

show abstract

“…It has long been thought, and has been confirmed by modern phylogenetic studies (Makimura et al, 1998;Makimura et al, 1999;Gräser et al, 1999;Summerbell et al, 1999) that pathogenic dermatophytes probably arose from soil-borne, nonpathogenic ancestors that are likely to be similar in habitat to today's nonpathogenic dermatophytoids (eg.…”

Section: Fungal Evolution and Antibiosismentioning

confidence: 96%

“…Why some species of dermatophytes have selected parasitic mode of existence while majority of dermatophytes species still live in soil as saprophytes is not known. The established homology between the obligate parasitic dermatophyte T. rubrum and strict saprophyte T. ajelloi (Rippon, 1988;Makimura et al, 1998;Makimura et al, 1999;Gräser et al, 1999;Summerbell et al, 1999) suggests the possibility of the past existence of the present day obligate parasitic dermatophytes in soil. Whenever, baiting technique is employed for isolation of dermatophytes from soil, Chrysosporium spp.…”

Section: T Ajelloi T Terrestre)mentioning

confidence: 99%

Does competition for existence pushed the evolution of the ‘once’ saprophytic fungi to parasitic life?

Sabesan¹,

Vallathol²,

Abbadorai³

et al. 2015

MJM

View full text Add to dashboard Cite

Aims:The current study was planned to understand how the 'once' saprophytic fungi would have adapted/equipped themselves to be pathogens in human environment and what environmental events that would have compelled/ facilitated certain fungi to become human pathogens. Methodology and results: Antibiosis of soil fungi such as Chrysosporium keratinophillum, Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus, Penicillium sp., Rhizopus oryzae and Curvularia lunata on different test fungi viz. different species of dermatophytes, Malassezia furfur, Cryptococcus neoformans and Histoplasma capsulatum was studied. In vitro susceptibility testing of secretory and intracellular substances of soil fungi was also tested on the test fungi of clinical significance. The ability of the test fungi for saprophytic survivability was tested on sterile and un-sterile soil. M. furfur and the anthrophilic dermatophytes were susceptible to the secretory substance and intracellular substances of the soil fungi. Conclusion, significance and impact study: The anthropophilic dermatophytes are not capable of existing in soil as saprophytes. The antagonistic effect of C. keratinophillum (sharing the same nutritional preference viz keratinophilic nature and ecological niche) could be one among the possible early events that formed the basis for the evolution of obligate parasitism in certain dermatophytes. Other obligate anthropophilic fungi, M. furfur is also not capable of existing even in sterile soil as a saprophyte. Most of the soil fungi tested show inhibition on M. furfur in vitro. The ability of fungi to cause disease in humans appears to be an accidental phenomenon With the exception of a few dermatophytes, pathogenicity among the molds is not necessary for the maintenance of dissemination of the species (Rippon, 1988). Further, the fungi that are able to cause disease seem to do so because of some peculiar trait of their metabolism that is not shared by taxonomically similar species. The survival and growth of fungi at the elevated temperature of the body, the reduced oxidation-reduction environment of tissue and the ability to overcome the host's defence mechanisms clearly sets 'mere' saprophytic and pathogenic fungi apart from each other. It is always of greater interest to know how these organisms would have adapted/equipped themselves to be pathogens in human environment and what environmental events that would have compelled/facilitated certain fungi to become human pathogens. This study reports the possible fungus-fungus interaction which would have been one of the driving forces of fungal evolution resulting in obligate anthropization of certain species.

show abstract

Phylogeny and taxonomy of the family Arthrodermataceae (dermatophytes) using sequence analysis of the ribosomal ITS region

Cited by 49 publications

References 14 publications

First Report of <i>Arthroderma benhamiae</i> in Switzerland

First Report of <i>Arthroderma benhamiae</i> in Switzerland

Dermatophytenspezies

Does competition for existence pushed the evolution of the ‘once’ saprophytic fungi to parasitic life?

Contact Info

Product

Resources

About