Phylogenomic, structural, and cell biological analyses reveal that
Stenotrophomonas maltophilia
replicates in acidified Rab7A-positive vacuoles of
Acanthamoeba castellanii
Javier Rivera,
Julio C. Valerdi-Negreros,
Diana M. Vázquez-Enciso
et al.
Abstract:Diverse
Acanthamoeba
lineages (genotypes) are of increasing clinical concern, mainly causing amoebic keratitis and granulomatous amebic encephalitis among other infections.
S. maltophilia
ranks among the top 10 most prevalent multidrug-resistant opportunistic nosocomial pathogens and is a recurrent member of the microbiome hosted by
Acanthamoeba
and other free-living amoebae. However, little is known about the molecular strategies deployed… Show more
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