2022
DOI: 10.1016/j.meegid.2022.105371
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Phylogenetic and drug- and vaccine-resistance profiles of Hepatitis B Virus among children with HIV co-infection in Pakistan

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“…A single A2189T mutation, associated with hepatocellular carcinoma, was found in the PC/core region ( 2 , 5 ). Two important amino acid changes, A128V and 144E, were found, which are associated with vaccine and/or diagnostic escape phenomena ( 6 , 7 ). The isolate was identified as genotype D and evolutionarily related to HBV strains from Bangladesh, Italy, and Estonia ( Fig.…”
Section: Announcementmentioning
confidence: 99%
“…A single A2189T mutation, associated with hepatocellular carcinoma, was found in the PC/core region ( 2 , 5 ). Two important amino acid changes, A128V and 144E, were found, which are associated with vaccine and/or diagnostic escape phenomena ( 6 , 7 ). The isolate was identified as genotype D and evolutionarily related to HBV strains from Bangladesh, Italy, and Estonia ( Fig.…”
Section: Announcementmentioning
confidence: 99%