Phylogenetic analysis of mammalian maximal oxygen consumption during exercise

Dlugosz, Elizabeth M.; Chappell, Mark A.; Meek, Thomas H.; Szafrańska, Paulina A.; Zub, Karol; Konarzewski, Marek; Jones, James H.; Bicudo, J. Eduardo P. W.; Nespolo, Roberto F.; Careau, Vincent; Garland, Theodore

doi:10.1242/jeb.088914

Cited by 67 publications

(61 citation statements)

References 116 publications

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“…The idea behind the development of the needed additional relations is that the variables associated directly with the "characteristic" capillary system described above can be expected to apply also to the capillaries of the ventricles, since their mass is proportional to body mass. Thus, the number of capillaries in the ventricles can be considered proportional to the number of capillaries n c associated with the Equations (7) and (8). The number of related cardiac cells in the ventricles can also be considered to be proportional to the number of capillaries supplying them.…”

Section: The Cardiovascular Systemmentioning

confidence: 99%

“…This could be the case if physiological variables such as oxygen consumption rate and heart rate increased by the same factor for all mammals. This is now known not to be the case as a result of work by Baudinette [35], Taylor and Weibel [36], Weibel and Hoppeler [37], Bishop [38,39] and, most recently, Dlugosz et al [8], among others.…”

Section: Effects Of Strenuous Exercisementioning

confidence: 99%

“…The present paper also involves discussion of the significance of these laws in understanding physiological processes of mammals. Earlier experimental measurements on various aspects of the cardiovascular system of mammals have been reported by Clark [1], Brody [2], Holt et al [3,4], Schmidt-Nielsen and Pennycuik [5], Gear et al [6] and Hoppeler et al [7], among OPEN ACCESS others; and more recent studies on related topics include those of Dlugosz [8], Seymour and Blaylock [9], White, Blackburn and Seymour [10] and White and Seymour [11], among others. Detailed theory providing insight into the subject has also been discussed by the writer in a number of publications [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

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Allometric Relations and Scaling Laws for the Cardiovascular System of Mammals

Dawson

2014

Systems

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Abstract:The modeling of the cardiovascular system of mammals is discussed within the framework of governing allometric relations and related scaling laws for mammals. An earlier theory of the writer for resting-state cardiovascular function is reviewed and standard solutions discussed for reciprocal quarter-power relations for heart rate and cardiac output per unit body mass. Variation in the basic cardiac process controlling heart beat is considered and shown to allow alternate governing relations. Results have potential application in explaining deviations from the noted quarter-power relations. The work thus indicates that the cardiovascular systems of all mammals are designed according to the same general theory and, accordingly, that it provides a quantitative means to extrapolate measurements of cardiovascular form and function from small mammals to the human. Various illustrations are included. Work described here also indicates that the basic scaling laws from the theory apply to children and adults, with important applications such as the extrapolation of therapeutic drug dosage requirements from adults to children.

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Section: The Cardiovascular Systemmentioning

confidence: 99%

Section: Effects Of Strenuous Exercisementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Allometric Relations and Scaling Laws for the Cardiovascular System of Mammals

Dawson

2014

Systems

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“…The use of treadmills, enclosed running wheels, air tunnels and water flues as well as open flow respirometry systems has resulted in a large number of MMR values for different-sized animals. The most recent analysis of MMR and body size of mammals [41] has shown that there is no significant difference between values obtained using treadmills or running wheels and found 0.84 to be the scaling exponent. The 95% confidence intervals (0.80-0.88) include values reported for mammals by two earlier studies; 0.81 by [42] and 0.87 by [43].…”

Section: Metabolic Rate and Body Size: Metabolic Rates Other Than Bmrmentioning

confidence: 99%

A Sceptics View: “Kleiber’s Law” or the “3/4 Rule” is neither a Law nor a Rule but Rather an Empirical Approximation

Hulbert

2014

Systems

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Early studies showed the metabolic rate (MR) of different-sized animals was not directly related to body mass. The initial explanation of this difference, the "surface law", was replaced by the suggestion that MR be expressed relative to mass n , where the scaling exponent "n" be empirically determined. Basal metabolic rate (BMR) conditions were developed and BMR became important clinically, especially concerning thyroid diseases. Allometry, the technique previously used to empirically analyse relative growth, showed BMR of endotherms varied with 0.73-0.74 power of body mass. Kleiber suggested that mass 3/4 be used, partly because of its easy calculation with a slide rule. Later studies have produced a range of BMR scaling exponents, depending on species measured. Measurement of maximal metabolism produced scaling exponents ranging from 0.80 to 0.97, while scaling of mammalian MR during growth display multi-phasic allometric relationships with scaling exponents >3/4 initially, followed by scaling exponents <3/4. There is no universal metabolic scaling exponent. The fact that "allometry" is an empirical technique to analyse relative change and not a biological law is discussed. Relative tissue size is an important determinant of MR. There is also a need to avoid simplistic assumptions regarding the allometry of surface area.

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“…The essential act of blood is to maintaining of hemostasis of internal tissues of body. A lot of actions are done in the body which changes the internal environment of chemical component, for example some changes will occur by contraction of muscles [5]. A cell that contains hemoglobin and can carry oxygen to the body.…”

Section: Introductionmentioning

confidence: 99%

Effect of isolated and combined training of aerobic and yoga on hemoglobin among school students

P.V

2017

IJPEFS

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Abstract:The purpose of the study was to find out the effect of isolated and combined training of aerobic and yoga on hemoglobin among school students. To achieve this purpose of the study, sixty female students were selected as subjects who were from the INDUS International School, Bangalore. The selected subjects were aged between 15 to 18 years. They were divided into four equal groups of fifteen each, Group I underwent aerobic training, Group II underwent yogic training, Group III underwent combined training and Group IV acted as control that did not participate in any special training apart from their regular curricular activities. The subjects were tested on selected criterion variable such as hemoglobin prior to and immediately after the training period. The selected criterion variable such as hemoglobin was determined through blood samples analyzed through laboratory tests. The analysis of covariance (ANCOVA) was used to find out the significant differences if any, between the experimental group and control group on selected criterion variable. In all the cases, 0.05 level of confidence was fixed to test the significance, which was considered as an appropriate. The result of the present study has revealed that there was a significant difference among the experimental and control group on hemoglobin..

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Phylogenetic analysis of mammalian maximal oxygen consumption during exercise

Abstract: SUMMARY We compiled published values of mammalian maximum oxygen consumption during exercise (V ·O2Supplementary material available online at http://jeb.biologists.org/lookup/suppl

Cited by 67 publications

References 116 publications

Allometric Relations and Scaling Laws for the Cardiovascular System of Mammals

Allometric Relations and Scaling Laws for the Cardiovascular System of Mammals

A Sceptics View: “Kleiber’s Law” or the “3/4 Rule” is neither a Law nor a Rule but Rather an Empirical Approximation

Effect of isolated and combined training of aerobic and yoga on hemoglobin among school students

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