Phyllodes tumour of the breast

Muttarak, M; Lerttumnongtum, P; Somwangjaroen, A; Chaiwun, Benjaporn

doi:10.2349/biij.2.2.e33

Cited by 7 publications

(4 citation statements)

References 6 publications

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“…However, there are no reliable mammographic or US features to differentiate benign from malignant phyllodes tumor. [ 7 ] On CT, a phyllodes tumor can appear as a heterogeneous enhancing mass which may contain solid and cystic components including irregular enhancing septations. [ 8 ] However, findings on imaging studies are not considered pathognomonic of phyllodes tumors.…”

Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumor with Chondrosarcomatous Differentiation: Radiological-Pathological Correlation

Murthy¹,

Chakravarthy²

2014

Journal of Clinical Imaging Science

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We present a case of a 63-year-old woman with malignant phyllodes tumor in her left breast. On imaging, a large, dumbbell-shaped, predominantly cystic mass with thin peripheral enhancement was noted. The lesion was causing rib destruction, chest wall invasion, and intrathoracic extension. These aggressive imaging features were considered highly suspicious of a malignant chest wall tumor. Subsequent chest wall resection of the tumor showed breast tissue with a biphasic lesion composed of proliferated spindle cells in loose sheets with extensive islands of atypical cartilage and a scanty epithelial component, including compressed ducts in the periphery of the lesion. A diagnosis of a malignant phyllodes tumor with stromal overgrowth and chondrosarcomatous differentiation was made in view of the presence of a benign epithelial component and negative reaction of the stromal component with a pancytokeratin. To the best of our knowledge, a phyllodes tumor with the radiological features of chest wall invasion and intrathoracic extension has not been described in the literature until now. Malignant phyllodes should be included in the list of differentials along with sarcomas on encountering lesions with such aggressive imaging features.

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Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumor with Chondrosarcomatous Differentiation: Radiological-Pathological Correlation

Murthy¹,

Chakravarthy²

2014

Journal of Clinical Imaging Science

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show abstract

“…[5] However, there are no reliable mammographic or US features to differentiate benign from malignant phyllodes tumor. [6] On CT, a phyllodes tumor can appear as a heterogeneous enhancing mass which may contain solid and cystic components including irregular enhancing septations. [7] They typically manifest as large, poorly marginated, infiltrative masses and are usually symptomatic.…”

Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumor Mimicking Metaplastic Carcinoma of Breast- A Case Report

Woike¹

2017

jmscr

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“…3 Treatment of phyllodes tumor requires complete removal of the tumor with wide margins if the tumor is small and the simple mastectomy may require in the large tumor. 11 Furthermore, excision with negative margins should be taken for recurrent and malignant phyllodes tumors. 12 Because of accurate preoperative diagnosis allows the correct surgical planning and avoidance of reoperation, the purposes of this study are to describe clinical presentation and radiologic features of phyllodes tumors and differentiate between benign and non-benign (borderline and malignant) groups.…”

Section: Introductionmentioning

confidence: 99%

Clinical presentation and radiologic imaging findings of phyllodes tumors: benign and borderline/malignant phyllodes tumors

Lohitvisate,

Rodjanakonkiat,

Kwankua

2024

F1000Res

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Background Phyllodes tumor is a rare fibroepithelial neoplasm of the breast, which is classified histologically as benign, borderline, or malignant. Accurate preoperative diagnosis allows the correct surgical planning and reoperation avoidance. Objective To describe the clinical presentation and radiologic features of phyllodes tumors and differentiate between benign and non-benign (borderline and malignant) groups. Methods A retrospective study of 57 patients with a diagnosis of phyllodes tumor who had preoperative imaging (mammography, ultrasound, or CT chest) and histological confirmation. The data was collected from 1 June 2011 to 30 September 2021. The imaging features of the phyllodes tumors were described according to the 5th edition of the ACR BI-RADS lexicon. For comparing between two groups, the student t-test, Wilcoxon rank sum test, Chi-square test, and Fisher’s exact test were used for statistical analyses. The logistic regression analysis was calculated for non-benign phyllodes tumor prediction. Results From 57 patients, the pathologic results were benign for 43 cases and non-benign phyllodes tumors for 14 cases. There was no differentiation of mammographic and CT features between benign and non-benign groups. Non-benign phyllodes tumors had the statistical significance of menopausal status, entire breast involvement, tumor size larger than 10 cm, and heterogeneous echo on univariable analysis. After multivariable analysis, menopausal status (odd ratios=13.79, p=0.04) and presence of vessels in the rim (odd ratios=16.51, p=0.019) or absent vascularity (odd ratios=8.45, p=0.047) on doppler ultrasound were significantly increased possibility of non-benign phyllodes tumor. Conclusions Menopausal status and presence of vessels in the rim or absent vascularity on Doppler ultrasound were important predictors for the diagnosis of non-benign phyllodes tumor.

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Phyllodes tumour of the breast

Cited by 7 publications

References 6 publications

Malignant Phyllodes Tumor with Chondrosarcomatous Differentiation: Radiological-Pathological Correlation

Malignant Phyllodes Tumor with Chondrosarcomatous Differentiation: Radiological-Pathological Correlation

Malignant Phyllodes Tumor Mimicking Metaplastic Carcinoma of Breast- A Case Report

Clinical presentation and radiologic imaging findings of phyllodes tumors: benign and borderline/malignant phyllodes tumors

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