Php39 Sensitivity of Medication Use and Outcomes to Formulary Controls in the Elderly: A Review of the Literature

Hypertension Medication and Medicare Beneficiaries: Prescription Drug Coverage Satisfaction and Medication Non-Adherence among Older Adults

“…Greater dissatisfaction with the amount paid for and the medications on the formulary significantly increased the risk of non-adherence in the present study. Cost and formulary restrictions have previously been found to impact adherence negatively [18]. Overcoming either issue is more complicated as it involves improved drug coverage, expanded formularies, and decreased out-of-pocket costs.…”

“…Men tend to be more non-adherent than women [16]. Restrictive formularies that reduce drug coverage and increase out-of-pocket costs can also lead to non-adherence among older adults [18]. Greater coverage promotes medication adherence among patients with Medicare which can stave off increased costs from further complications and acute cardiovascular diseases [14,[18][19][20][21].…”

Impact of Cost‐Sharing Increases on Continuity of Specialty Drug Use: A Quasi‐Experimental Study

“…Thus, increases in cost sharing appeared to represent an additional adherence barrier and exacerbate existing issues. We captured gaps in treatment, yet high costs can also put patients at risk of altering their treatment regimens in more minor ways that would not have been captured in our analysis (e.g., skipping doses), a phenomenon that has been observed in seniors with higher out-of-pocket medication costs (Steinman, Sands, and Covinsky 2001;Shenolikar et al 2011). Further, anxiety related to the affordability of continuous access to treatment may be clinically relevant in light of the link between stress and symptom exacerbations in MS and other chronic diseases (Mohr et al 2004;Cohen, Janicki-Deverts, and Miller 2007;Fogarty et al 2015).…”

Protocol for a randomised controlled trial evaluating the effects of providing essential medicines at no charge: the Carefully seLected and Easily Accessible at No Charge Medicines (CLEAN Meds) trial

“… 5 For US Medicare beneficiaries, a review of 47 studies found that greater drug coverage and decreased patient cost sharing improved medicine adherence. 6 Providing medicines at no charge to patients reporting cost-related non-adherence may improve medicine adherence and clinical outcomes, particularly for the elderly, vulnerable individuals and those with chronic diseases. 6 7 There is limited literature that evaluates the impact on adherence of providing medicines at no charge.…”

“… 6 Providing medicines at no charge to patients reporting cost-related non-adherence may improve medicine adherence and clinical outcomes, particularly for the elderly, vulnerable individuals and those with chronic diseases. 6 7 There is limited literature that evaluates the impact on adherence of providing medicines at no charge. 7 In the Post-Myocardial Infarction Free Rx Event and Economic Evaluation (MI FREEE) trial, which was conducted in a highly selected group of post-myocardial infarction patients and only involved antiplatelet, beta-blockers, ACE inhibitors, angiotensin receptor blockers and statins, the absolute adherence for all patients in the full coverage intervention group (43.9%±33.7%) was 5.4% (adjusted, 95% CI 3.6% to 7.2%; p<0.001) higher compared with the usual coverage control group (38.9%±32.7%).…”