Phototrophic CO2 Fixation: Recent Insights into Ancient Metabolisms

Hanson, Thomas E.; Alber, Birgit E.; Tabita, F. Robert

doi:10.1007/978-94-007-1533-2_9

Cited by 39 publications

(4 citation statements)

References 140 publications

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“…Only type IV RubisCO, which does not fix CO 2 , cannot perform oxygenase activity (Hanson et al . ). High CO 2 levels and/or low O 2 levels lower oxygenase activity.…”

Section: Introductionmentioning

confidence: 97%

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Evolution of the biochemistry of the photorespiratory C2 cycle

et al. 2012

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Oxygenic photosynthesis would not be possible without photorespiration in the present day O2 -rich atmosphere. It is now generally accepted that cyanobacteria-like prokaryotes first evolved oxygenic photosynthesis, which was later conveyed via endosymbiosis into a eukaryotic host, which then gave rise to the different groups of algae and streptophytes. For photosynthetic CO2 fixation, all these organisms use RubisCO, which catalyses both the carboxylation and the oxygenation of ribulose 1,5-bisphosphate. One of the reaction products of the oxygenase reaction, 2-phosphoglycolate (2PG), represents the starting point of the photorespiratory C2 cycle, which is considered largely responsible for recapturing organic carbon via conversion to the Calvin-Benson cycle (CBC) intermediate 3-phosphoglycerate, thereby detoxifying critical intermediates. Here we discuss possible scenarios for the evolution of this process toward the well-defined 2PG metabolism in extant plants. While the origin of the C2 cycle core enzymes can be clearly dated back towards the different endosymbiotic events, the evolutionary scenario that allowed the compartmentalised high flux photorespiratory cycle is uncertain, but probably occurred early during the algal radiation. The change in atmospheric CO2 /O2 ratios promoting the acquisition of different modes for inorganic carbon concentration mechanisms, as well as the evolutionary specialisation of peroxisomes, clearly had a dramatic impact on further aspects of land plant photorespiration.

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“…Only type IV RubisCO, which does not fix CO 2 , cannot perform oxygenase activity (Hanson et al . ). High CO 2 levels and/or low O 2 levels lower oxygenase activity.…”

Section: Introductionmentioning

confidence: 97%

“…All RubisCO types found in oxygenic phototrophs catalyse both the carboxylase and oxygenase reactions. Only type IV RubisCO, which does not fix CO 2 , cannot perform oxygenase activity (Hanson et al 2012). High CO 2 levels and/or low O 2 levels lower oxygenase activity.…”

Section: Introductionmentioning

confidence: 99%

Evolution of the biochemistry of the photorespiratory C2 cycle

et al. 2012

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“…The transcriptional regulators, CmpR (Sll0030), CcmR (aka NdhR, Slr1594), and Sll0822 are implicated in the control of expression of the low carbon (LC) inducible genes of the CCM [11] , [15] – [18] . CmpR and CcmR exhibit homology to CbbR, a LysR family transcriptional regulator of the CO 2 fixation genes in chemoautotrophic and anoxygenic photoautotrophs [19] . Sll0822 is a member of the AbrB family of transcriptional regulators and appears to function as a repressor of the expression of NDH-I 3 and SbtA [18] .…”

Section: Introductionmentioning

confidence: 99%

Regulation of the Cyanobacterial CO2-Concentrating Mechanism Involves Internal Sensing of NADP+ and α-Ketogutarate Levels by Transcription Factor CcmR

et al. 2012

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Inorganic carbon is the major macronutrient required by organisms utilizing oxygenic photosynthesis for autotrophic growth. Aquatic photoautotrophic organisms are dependent upon a CO 2 concentrating mechanism (CCM) to overcome the poor CO 2 -affinity of the major carbon-fixing enzyme, ribulose-bisphosphate carboxylase/oxygenase (Rubisco). The CCM involves the active transport of inorganic forms of carbon (C i ) into the cell to increase the CO 2 concentration around the active site of Rubisco. It employs both bicarbonate transporters and redox-powered CO 2 -hydration enzymes coupled to membranous NDH-type electron transport complexes that collectively produce C i concentrations up to a 1000-fold greater in the cytoplasm compared to the external environment. The CCM is regulated: a high affinity CCM comprised of multiple components is induced under limiting external Ci concentrations. The LysR-type transcriptional regulator CcmR has been shown to repress its own expression along with structural genes encoding high affinity C i transporters distributed throughout the genome of Synechocystis sp. PCC 6803. While much has been learned about the structural genes of the CCM and the identity of the transcriptional regulators controlling their expression, little is known about the physiological signals that elicit the induction of the high affinity CCM. Here CcmR is studied to identify metabolites that modulate its transcriptional repressor activity. Using surface plasmon resonance (SPR) αketoglutarate (α-KG) and the oxidized form of nicotinamide adenine dinucleotide phosphate (NADP + ) have been identified as the co-repressors of CcmR. Additionally, ribulose1,5bisphosphate (RuBP) and 2phosphoglycolate (2PG) have been confirmed as co-activators of CmpR which controls the expression of the ABC-type bicarbonate transporter.

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“…Although the relative contribution of microbial carbon fixation by the CBB‐pathway relative to rTCA and other enzymatic pathways remains uncertain in some settings (Campbell, Engel, Porter, & Takai, ; Hanson, Alber, & Tabita, ; Luo et al., ; Van Der Meer, Schouten, De Leeuw, & Ward, ), in general, the total organic carbon (TOC) isotope record of the Proterozoic and Phanerozoic is consistent with dominance of the CBB cycle through most of Earth history (Hayes, Strauss, & Kaufman, ). The bulk δ 13 C TOC record of a CBB‐driven ecosystem includes all sources that produce and assimilate this carbon, including both oxygenic and anoxygenic phototrophs, and heterotrophic consumers.…”

Section: Introductionmentioning

confidence: 99%

Geochemically distinct carbon isotope distributions in Allochromatium vinosum DSM 180^T grown photoautotrophically and photoheterotrophically

et al. 2017

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Anoxygenic, photosynthetic bacteria are common at redox boundaries. They are of interest in microbial ecology and geosciences through their role in linking the carbon, sulfur, and iron cycles, yet much remains unknown about how their flexible carbon metabolism-permitting either autotrophic or heterotrophic growth-is recorded in the bulk sedimentary and lipid biomarker records. Here, we investigated patterns of carbon isotope fractionation in a model photosynthetic sulfur-oxidizing bacterium, Allochromatium vinosum DSM180 . In one treatment, A. vinosum was grown with CO as the sole carbon source, while in a second treatment, it was grown on acetate. Different intracellular isotope patterns were observed for fatty acids, phytol, individual amino acids, intact proteins, and total RNA between the two experiments. Photoautotrophic CO fixation yielded typical isotopic ordering for the lipid biomarkers: δ C values of phytol > n-alkyl lipids. In contrast, growth on acetate greatly suppressed intracellular isotopic heterogeneity across all molecular classes, except for a marked C-depletion in phytol. This caused isotopic "inversion" in the lipids (δ C values of phytol < n-alkyl lipids). The finding suggests that inverse δ C patterns of n-alkanes and pristane/phytane in the geologic record may be at least in part a signal for photoheterotrophy. In both experimental scenarios, the relative isotope distributions could be predicted from an isotope flux-balance model, demonstrating that microbial carbon metabolisms can be interrogated by combining compound-specific stable isotope analysis with metabolic modeling. Isotopic differences among molecular classes may be a means of fingerprinting microbial carbon metabolism, both in the modern environment and the geologic record.

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Phototrophic CO2 Fixation: Recent Insights into Ancient Metabolisms

Cited by 39 publications

References 140 publications

Evolution of the biochemistry of the photorespiratory C2 cycle

Evolution of the biochemistry of the photorespiratory C2 cycle

Regulation of the Cyanobacterial CO2-Concentrating Mechanism Involves Internal Sensing of NADP+ and α-Ketogutarate Levels by Transcription Factor CcmR

Geochemically distinct carbon isotope distributions in Allochromatium vinosum DSM 180^T grown photoautotrophically and photoheterotrophically

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Phototrophic CO2 Fixation: Recent Insights into Ancient Metabolisms

Cited by 39 publications

References 140 publications

Evolution of the biochemistry of the photorespiratory C2 cycle

Evolution of the biochemistry of the photorespiratory C2 cycle

Regulation of the Cyanobacterial CO2-Concentrating Mechanism Involves Internal Sensing of NADP+ and α-Ketogutarate Levels by Transcription Factor CcmR

Geochemically distinct carbon isotope distributions in Allochromatium vinosum DSM 180T grown photoautotrophically and photoheterotrophically

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Geochemically distinct carbon isotope distributions in Allochromatium vinosum DSM 180^T grown photoautotrophically and photoheterotrophically