Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends

Kadkhoda, Jamileh; Tarighatnia, Ali; Tohidkia, Mohammad Reza; Nader, Nader D.; Aghanejad, Ayuob

doi:10.1016/j.lfs.2022.120499

Cited by 42 publications

(20 citation statements)

References 102 publications

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“…The current therapeutic approaches for BC mainly consist of chemotherapy, hormone therapy, and surgery ( Aghanejad et al, 2013 ; Kadkhoda et al, 2022 ; Zhong et al, 2022 ). However, disadvantages such as adverse side effects for patients, drug resistance, and residual tumor cells greatly limit their therapeutic effect and may lead to cancer recurrence ( Waks and Winer, 2019 ; Kadkhoda et al, 2021 ).…”

Section: Photothermal Therapymentioning

confidence: 99%

“…By irradiating photothermal agents under near-infrared (NIR) light, hyperthermia can be triggered to kill cancer cells in target tissues by energy transfer through electron–phonon and electron–electron relaxation of photothermal agents that increase temperature, with both primary tumors and early local metastasis being potential targets. PTT can effectively suppress BC by activating apoptosis, autophagy, or suppressing cell signaling to induce cell death with a shorter treatment time, which reduces patient pain and possesses desirable therapeutic effects with fewer side effects ( Kadkhoda et al, 2022 ). Moreover, when combining PTT with chemotherapy and/or photodynamic therapy, an enhanced synergistic therapeutic effect can be achieved in both primary and metastatic BC tumors ( Zhou et al, 2015b ; Guo et al, 2015 ; Lin et al, 2015 ; Liu et al, 2019 ; Deng et al, 2021 ) ( Figure 1 ).…”

Section: Photothermal Therapymentioning

confidence: 99%

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Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer

Sun

Zhao

et al. 2022

Front. Chem.

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Breast cancer (BC) is one of the most common cancers in women worldwide; however, the successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a significant clinical challenge. Recently, photothermal therapy (PTT), which involves the generation of heat under irradiation to achieve photothermal ablation of BC with minimal invasiveness and outstanding spatial–temporal selectivity, has been demonstrated as a novel therapy that can overcome the drawbacks of chemotherapy or surgery. Significantly, when combining PTT with chemotherapy and/or photodynamic therapy, an enhanced synergistic therapeutic effect can be achieved in both primary and metastatic BC tumors. Thus, this review discusses the recent developments in nanotechnology-based photothermal therapy for the treatment of BC and its metastasis to provide potential strategies for future BC treatment.

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Section: Photothermal Therapymentioning

confidence: 99%

Section: Photothermal Therapymentioning

confidence: 99%

Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer

Sun

Zhao

et al. 2022

Front. Chem.

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“…However, it is still difficult to combine hyperthermia with other therapies in a consistent, efficient and structured way, which is a clinical challenge that needs to be overcome ( Meng et al, 2022a ). Photothermal therapy (PTT) is capable of non-invasive thermal ablation of cancers mediated by photothermal converters and has been shown to be an emerging therapy for selective killing of cancer cells with the advantages of high efficiency, high stability, high temporal and spatial selectivity, and low invasive load ( Kadkhoda et al, 2022 ; Sun et al, 2022 ). Photodynamic therapy (PDT) is able to kill cancer cells oxidatively and induce their immunogenic death with the help of photosensitizers that produce reactive oxygen species ( Zhou et al, 2022a ; Zhou et al, 2022b ).…”

Section: Introductionmentioning

confidence: 99%

Hydrogel systems for targeted cancer therapy

et al. 2023

Front. Bioeng. Biotechnol.

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When hydrogel materials with excellent biocompatibility and biodegradability are used as excellent new drug carriers in the treatment of cancer, they confer the following three advantages. First, hydrogel materials can be used as a precise and controlled drug release systems, which can continuously and sequentially release chemotherapeutic drugs, radionuclides, immunosuppressants, hyperthermia agents, phototherapy agents and other substances and are widely used in the treatment of cancer through radiotherapy, chemotherapy, immunotherapy, hyperthermia, photodynamic therapy and photothermal therapy. Second, hydrogel materials have multiple sizes and multiple delivery routes, which can be targeted to different locations and types of cancer. This greatly improves the targeting of drugs, thereby reducing the dose of drugs and improving treatment effectiveness. Finally, hydrogel can intelligently respond to environmental changes according to internal and external environmental stimuli so that anti-cancer active substances can be remotely controlled and released on demand. Combining the abovementioned advantages, hydrogel materials have transformed into a hit in the field of cancer treatment, bringing hope to further increase the survival rate and quality of life of patients with cancer.

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“…For decades, effective implementation strategies have been developed to optimize the advancements in the fields of tumor survivorship, diagnosis, treatment, and end-of-life care [10]. For instance, a series of treatments have been developed to conquer cancers with high uncontrolled cell division and heterogeneity, including surgery (e.g., laparoscopic rectal surgery and robotic surgery) [11,12], photothermal therapy (PTT) [13][14][15], radiotherapy [16], chemotherapy [17], oncolytic virotherapy [18], RNA vaccine [19,20], hormone therapy [21], peptide-based neoantigen vaccine [22,23], gene therapy [24][25][26], immunotherapy (e.g., immune cells and checkpoint inhibitors) [2], and even nanomaterial-mediated nanotheranostics (e.g., organic nanomaterials, inorganic nanomaterials, and organic-inorganic hybrid nanomaterials). Nevertheless, the aforementioned strategies have also revealed inherent shortcomings (e.g., severe toxicity, off-target effects, graft-versus-host disease, and drug delivery barriers), which collectively hinder the further improvement in cancer administration [27,28].…”

Section: Introductionmentioning

confidence: 99%

Natural Killer Cells for Cancer Immunotherapy: Opportunities and Challenges

Zhang¹,

Feng²,

Han³

et al. 2023

Natural Killer Cells - Lessons and Challenges

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Natural killer (NK) cells are advantaged immune cells and play a pivotal role in both innate and adaptive immune responses. To date, autogenous and allogenic NK cells have been generated from a variety of origins, including perinatal blood (e.g., umbilical cord blood and placental blood), peripheral blood, and even stem cells (hematopoietic stem cells and pluripotent stem cells). NK cells function mainly via antibody-dependent cell-mediated cytotoxicity (ADCC), direct cytolytic effect, and paracrine effects (e.g., IFN-γ, GM-CSF, granzyme, and perforin). Distinguishing from the adaptive immunizing cells (e.g., T and B lymphocytes), NK cells, and chimeric antigen receptor-transduced NK (CAR-NK), cell-based cytotherapy is adequate to fulfill the biofunction of eliminating pathogenic infection, combating hematological malignancies and metastatic solid tumors, and delaying aging. In this chapter, we mainly focus on the state-of-the-art renewal of NK cell-based cytotherapy for cancer immunosurveillance and immunotherapy from the view of high-efficient in vitro preparation (e.g., candidate cell sources and ex vivo cultivation) and preclinical and clinical investigation. Furthermore, we also figure out the promising prospects and the concomitant challenges of NK cell-based remedies for cancer management in future, which will collectively benefit the development of NK cell-based cancer immunotherapy in future.

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Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends

Cited by 42 publications

References 102 publications

Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer

Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer

Hydrogel systems for targeted cancer therapy

Natural Killer Cells for Cancer Immunotherapy: Opportunities and Challenges

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