Photothermal Backscatter Interferometry for Enhanced Detection in Capillary Electrophoresis
Prabhavie M. Opallage,
Miyuru De Silva,
Stanslaus M. Kariuki
et al.
Abstract:Refractive index (RI) detection using backscatter interferometry (BSI) enables universal detection in capillary electrophoresis (CE). BSI detection is a versatile on-capillary approach that is easily integrated with capillary or microfluidic channels, straightforward to miniaturize, and inexpensive. The focused BSI light source can also double as the excitation source for fluorescence, enabling simultaneous universal (BSI) and specific (fluorescence) signals from the same detection volume. To improve BSI detec… Show more
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