Photothermal Aza‐Michael Addition of Divergent Amines to Vinyl Sulfones: A Method Towards Transition Metal‐ and Base‐Free Medium

Abstract

A highly efficient and versatile method has been developed for the photothermal aza‐Michael addition, producing β‐amino sulfones with excellent yields. The protocol uses mild and simple conditions under the batch and continuous flow process, and is suitable for synthesis, without the need for transition metal catalysts, ligands, strong acids, or bases. This sustainable approach offers a a significant breakthrough in organic synthesis with potential applications in medicinal chemistry and materials science.