Photothermal Ablation of Stem-Cell Like Glioblastoma Using Carbon Nanotubes Functionalized with Anti-CD133

Wang, Chung‐Hao; Huang, Yao-Jhang; Peng, Ching‐An

doi:10.1007/978-3-540-92841-6_219

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Microelectrodes coated with CNTs show enhanced sensitivity in neuronal activity recordings compared to state of the art devices (Keefer et al, 2008 ; Jan et al, 2009 ; Luo et al, 2011 ). Finally, CNTs are also able to deliver functional molecules inside neurons (Kateb et al, 2007 ; Wang C.-H. et al, 2009 ; Cellot et al, 2010 ; Ren et al, 2012 ).…”

Section: Carbon Nanotubesmentioning

confidence: 99%

Carbon Nanomaterials Interfacing with Neurons: An In vivo Perspective

et al. 2016

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Developing new tools that outperform current state of the art technologies for imaging, drug delivery or electrical sensing in neuronal tissues is one of the great challenges in neurosciences. Investigations into the potential use of carbon nanomaterials for such applications started about two decades ago. Since then, numerous in vitro studies have examined interactions between these nanomaterials and neurons, either by evaluating their compatibility, as vectors for drug delivery, or for their potential use in electric activity sensing and manipulation. The results obtained indicate that carbon nanomaterials may be suitable for medical therapies. However, a relatively small number of in vivo studies have been carried out to date. In order to facilitate the transformation of carbon nanomaterial into practical neurobiomedical applications, it is essential to identify and highlight in the existing literature the strengths and weakness that different carbon nanomaterials have displayed when probed in vivo. Unfortunately the current literature is sometimes sparse and confusing. To offer a clearer picture of the in vivo studies on carbon nanomaterials in the central nervous system, we provide a systematic and critical review. Hereby we identify properties and behavior of carbon nanomaterials in vivo inside the neural tissues, and we examine key achievements and potentially problematic toxicological issues.

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Section: Carbon Nanotubesmentioning

confidence: 99%

Carbon Nanomaterials Interfacing with Neurons: An In vivo Perspective

et al. 2016

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Nanomedicine and Brain Tumors Treatment

Caruso

Caffo

Raudino

et al. 2012

Patenting Nanomedicines

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Patented Nanomedicines for the Treatment of Brain Tumors

Caruso

Raudino

Caffo

2013

Pharm. Pat. Analyst

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Patients affected by malignant brain tumors present an extremely poor prognosis, notwithstanding improvements in surgery techniques and therapeutic protocols. Brain tumor treatment has been principally hampered by limited drug delivery across the blood-brain barrier (BBB). An efficacious chemotherapeutic treatment requires a pharmacological agent that can penetrate the BBB and target neoplastic cells. Nanotechnology involves the design, synthesis and characterization of materials that have a functional organization in at least one dimension on the nanometer scale. Nanoparticle systems can represent optimal devices for delivery of various drugs into the brain across the BBB. Nanoparticle drug-delivery systems can also be used to provide targeted delivery of drugs, improve bioavailability and sustain release of drugs for systemic delivery. In this patent review, the recent studies of certain nanoparticle systems in treatment of brain tumors are summarized. Common nanoparticles systems include polymeric nanoparticles, lipid nanoparticles and inorganic nanoparticles. Various patents of nanoparticle systems able to across the BBB to target brain tumors are also reported and discussed.

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Photothermal Ablation of Stem-Cell Like Glioblastoma Using Carbon Nanotubes Functionalized with Anti-CD133

Cited by 3 publications

References 5 publications

Carbon Nanomaterials Interfacing with Neurons: An In vivo Perspective

Carbon Nanomaterials Interfacing with Neurons: An In vivo Perspective

Nanomedicine and Brain Tumors Treatment

Patented Nanomedicines for the Treatment of Brain Tumors

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