Phototherapy in the blue range of visible spectrum: the possibilities of optimization of the functional state of the cardiorespiratory system in humans under extreme conditions

Abstract

It was recently shown that perception of the blue part of visible spectrum is mediated by melanopsins localized not only in the retina, but also in cells of the vascular wall. We have studied changes in the human cardiorespiratory system under the influence of light with a wavelength of 470  10 nm in normal life and under extreme conditions of high-latitude marine expeditions (2017 and 2019). Using the method of spiroarteriocardiorhythmography (SACR), we recorded parameters of the cardiorespiratory system at rest and under conditions of stress tests; the time of recording was 2 min in all cases. The changes in the studied indicators over 26-40 days were assessed. Registration by SACR without (at rest) and with the spirometric mask under conditions of normal breathing revealed no effect of phototherapy. However, registration during the test with controlled breathing at a rate of 6 cycles per minute in all 3 series of our experiment revealed statistically significant effect of photostimulation on individual parameters; the same was found by discriminant analysis. In ordinary life, the dynamics of baroreflex sensitivity was significant for the differentiation of the experimental groups. Under extreme conditions of Arctic expeditions, apart from baroreflex sensitivity, significant differences were found in the dynamics of blood pressure, heart rate, and spectral parameters of their variability. The overall direction of these shifts reflects strengthening of the adaptive capacities of the cardiorespiratory system in participants of the experimental groups.

Effects of optoelectronic blue range irradiation at the human body (literature review)

“…Сеансы профилактической фототерапии синим светом способствуют активации функциональных резервов организма человека при адаптации к климатогеографическим факторам и напряженной физической деятельности [4,5].…”