Phototherapy as an effective treatment for Majocchi's disease - Case report

Abstract

Pigmented purpuric dermatoses are chronic and relapsing disorders characterized by a symmetrical rash of petechial and pigmentary macules, mainly confined to the lower limbs. Purpura annularis telangiectodes of Majocchi is a less common variant of Pigmented purpuric dermatoses characterized by punctate telangiectatic macules progressing to annular, hyperpigmented patches with central clearing and infrequent atrophy. A 12 year-old girl presented with asymptomatic round to oval reddish brown macules, present symmetrically over her lower and upper limbs for 3 years. Few lesions were annular in shape. Biopsy from the lesion was compatible with Pigmented purpuric dermatoses. On the basis of clinical and histopathological findings, a diagnosis of Purpura annularis telangiectodes of Majocchi was made. The patient began phototherapy thrice a week and showed excellent response.

Therapeutic Approach in Pigmented Purpuric Dermatoses—A Scoping Review

“…The treatment typically involved fewer than 30 sessions, with cumulative doses ranging from 29 [ 71 ] to 200 J/cm 2 [ 42 ]. PUVA has also shown effectiveness in conditions such as lichen aureus [ 72 ], Majocchi disease [ 73 ], pigmented purpuric lichenoid dermatosis of Gougerot and Blum [ 74 ] and unilateral linear capillaritis [ 75 ].…”

Purpura anularis teleangiectodes

“…Das Spektrum reicht von Antibiotika [ 2 ] über Retinoide [ 8 ] bis hin zu einer durch eine Sklerotherapie ausgelösten PAT [ 3 ]. In diesen Fällen führte ein Absetzen des auslösenden Medikaments zum progredienten Verblassen der Hautveränderungen [ 6 ].…”

“…Im Jahr 2015 wurde erstmalig eine Therapie der PAT mittels PUVA und Schmalband-UVB beschrieben [ 2 ]; 2009 beschrieben Hoesly et al. einen therapierefraktären Fall der PAT, der letztlich durch eine Therapie mit Methotrexat 15 mg innerhalb von 4 Wochen zu einer gänzlichen Abheilung kam [ 3 ].…”

A case of pigmented purpuric dermatosis similar to mycosis fungoides

“…The patient was recovered by these treatments, his itching complaints and PPD lesions were completely resolved at the end of first month of the treatment. [10][11][12][13][14]. This study shows that purpuric pigmented dermatitis can be associated to or evolve into lymphoproliferative disease and mycosis fungoides.…”