Phototherapeutic keratectomy with mitomycin C after Descemet stripping automated endothelial keratoplasty

Hongyok, Teeravee; Kim, Alisa; Jun, Albert S.; Ladas, John G.; Chuck, Roy S.

doi:10.1136/bjo.2009.165951

Cited by 9 publications

(7 citation statements)

References 5 publications

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“…Hongyok and coworkers also reported significant improvement in visual acuity and corneal clarity after PTK with MMC for subepithelial fibrosis persisting after Descemet stripping endothelial keratoplasty. 66 None of the eyes experienced any recurrence of fibrosis for a period of up to 12 months after surgery.…”

Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 86%

“…99,141 PTK has been used for managing anterior stromal changes in such eyes. 15,66,99 Anterior surface irregularities in these eyes are caused by a reticular network of subepithelial fibroblasts, causing anterior corneal surface aberrations and subepithelial haze. 6,125 Highorder aberrations from the anterior corneal surface have been seen to be higher in eyes requiring Descemet stripping endothelial keratoplasty for Fuchs dystrophy than in agematched controls.…”

Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 99%

“…The procedure can be combined with the adjuvant use of intraoperative mitomycin-C (MMC) to prevent laser-induced haze formation. 66,99 2.10. PTK in pediatric cases PTK has been tried in children for the management of various corneal pathologies including anterior corneal scars, corneal dystrophies, and band keratopathy.…”

Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 99%

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Phototherapeutic keratectomy

Nagpal

Maharana

Roop

et al. 2020

Survey of Ophthalmology

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Phototherapeutic keratectomy is an excimer laserebased surgical procedure widely performed by corneal surgeons for treating anterior corneal stromal pathologies. Phototherapeutic keratectomy helps by ablating the corneal stroma, thereby improving corneal clarity and smoothening the surface. Transient discomfort and induced hyperopia from corneal flattening are the immediate postoperative concerns. The long-term course is often marked by the recurrence of original corneal pathology and corneal haze formation. Phototherapeutic keratectomy, however, allows for repeat stromal ablation for managing recurrences, as the corneal thickness permits, without affecting the outcome of future keratoplasty. Adjunctive methods such as topical mitomycin-C may be additionally used to reduce recurrence rates. Also, various masking agents such as carboxymethyl cellulose, sodium hyaluronate, and dextran are used in eyes with irregular corneal surface to allow for uniform stromal ablation. Overall, phototherapeutic keratectomy has provided corneal surgeons an additional surgical tool, particularly those residing in developing nations where the availability of donor corneal tissue is an important limiting factor.

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Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 86%

Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 99%

Section: Ptk After Descemet Stripping Endothelial Keratoplastymentioning

confidence: 99%

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Phototherapeutic keratectomy

Nagpal

Maharana

Roop

et al. 2020

Survey of Ophthalmology

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“…We have had a few patients (not included in this study) who also had subepithelial scarring evident on slit-lamp examination. These patients were successfully treated with phototherapeutic keratectomy (PTK) with improvement in vision [17]. Another recent Pentacam analysis of DSEK eyes found a relationship was between higher order anterior surface topographic corneal irregularities and post-operative vision [18].…”

Section: Discussionmentioning

confidence: 99%

Correlation of Corneal Parameters and Visual Acuity Outcomes after Descemet Stripping Endothelial Keratoplasty

Srikumaran¹

2013

J Clin Exp Ophthalmol

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Previous studies in patients with lamellar endothelial keratoplasty have demonstrated a reduction in visual acuity secondary to increased corneal light scattering [8-10]. It has been hypothesized that optical aberrations and haze at the graft-host interface or corneal surface may account for the reduced postoperative best-corrected visual acuity in patients following DSEK [7]. However, surface and interface haze (clinical or sub-clinical) may not be apparent on slit-lamp examination. Even when present, the degree of haze can be difficult to grade objectively and reproducibly, making inter-patient or intra-patient comparisons across time extremely difficult. The development or validation of a

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“…There is a report of PTK being performed for the subepithelial fibrosis along with the use of MMC after DSAEK. [105]…”

Section: Phototherapeutic Keratectomy Combined With or Before And Aftmentioning

confidence: 99%

Phototherapeutic keratectomy

Rathi

Vyas

Sangwan

2012

Indian J Ophthalmol

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Phototherapeutic keratectomy (PTK) is done regularly for anterior corneal diseases such as corneal dystrophies, corneal degenerations, scars, and band-shaped keratopathy. The various indications include both therapeutic and visual. The aim of this article is to discuss the therapeutic indications for PTK, the specific technique pertaining to a specific etiology, the various other procedures like amniotic membrane graft combined with PTK or PTK being done for recurrences in the grafts, and PTK done before cataract surgery when the anterior corneal pathology coexists with the cataract. Post PTK management such as healing of an epithelial defect, use of steroids in the post PTK period, recurrences of primary disease pathology, and infections, will be discussed. Methods of literature search: A Medline search was carried out for articles in the English language, with the keywords, phototherapeutic keratectomy, band-shaped keratopathy, spheroidal degeneration, scars, bullous keratopathy, and corneal dystrophy. The relevant references are mentioned here.

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Phototherapeutic keratectomy with mitomycin C after Descemet stripping automated endothelial keratoplasty

Cited by 9 publications

References 5 publications

Phototherapeutic keratectomy

Phototherapeutic keratectomy

Correlation of Corneal Parameters and Visual Acuity Outcomes after Descemet Stripping Endothelial Keratoplasty

Phototherapeutic keratectomy

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