Photosynthetic and Self‐Draining Biohybrid Dressing for Accelerating Healing of Diabetic Wound
Xinyu Ren,
Zhiming Hou,
Bo Pang
et al.
Abstract:Wound healing is a well‐orchestrated progress associated with angiogenesis, epithelialization, inflammatory status, and infection control, whereas these processes are seriously disturbed in diabetic wounds. In this study, a biohybrid dressing integrating the inherent ability of Bromeliad leaf (photosynthesis and self‐draining) with the therapeutic effect of artificial materials (glucose‐degrading and ROS‐scavenging) is presented. The dressing consists of double‐layered structures as follows: 1) Outer layer, a … Show more
“…Similarly, Ren et al combined the inherent abilities of bromeliades leaves ( photosynthesis and self-drainage) with the therapeutic effects of artificial materials (glucose degradation and ROS clearance) to develop double-layer microneedles for diabetic wound repair. 115 The abundant chloroplasts in the outer layer produce enough oxygen to cope with the hypoxia of the wound and enhance the glucose degradation catalyzed by GOx. The leaf conducting tissue can discharge the excessive exudate from the wound and form a favorable microenvironment for wound management.…”
Chronic non-healing wounds are a common consequence of skin ulceration in diabetic patients, with severe cases such as diabetic foot even leading to amputations. The interplay between pathological factors like...
“…Similarly, Ren et al combined the inherent abilities of bromeliades leaves ( photosynthesis and self-drainage) with the therapeutic effects of artificial materials (glucose degradation and ROS clearance) to develop double-layer microneedles for diabetic wound repair. 115 The abundant chloroplasts in the outer layer produce enough oxygen to cope with the hypoxia of the wound and enhance the glucose degradation catalyzed by GOx. The leaf conducting tissue can discharge the excessive exudate from the wound and form a favorable microenvironment for wound management.…”
Chronic non-healing wounds are a common consequence of skin ulceration in diabetic patients, with severe cases such as diabetic foot even leading to amputations. The interplay between pathological factors like...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.