Photosensitization Induced by Monoglycerol Paraaminobenzoate

Reviews : The Happy Foot, by R. Barth, L. Campbell, S. Allen, and J. Jupp (1988), The Diabetes Centre, St. Vincent's Hospital, 372 Victoria Street, Darlinghurst, NSW 2010, Australia. Manual, appendices, and 35 mm slides. Price: Not available

“…In the 1960s and 1970s, antibacterial and antifungal agents, especially the halogenated salicylanilides, were included in antibacterial bar soaps, cleansers and other personal care products. [12][13][14] Reports of photoallergy to these agents soon led to their removal from the manufacturing of sunscreens and the marketing of PABA-free products, primarily containing benzophenones as an alternative. The most sensitizing of these (tetrachlorosalicylanilide and tribromosalicylanilide) have been removed from personal care products.…”

“…The first sunscreen agents to gain wide usage were PABA and, later, its esters octyl dimethyl PABA and pentyl dimethyl PABA. [12][13][14] Reports of photoallergy to these agents soon led to their removal from the manufacturing of sunscreens and the marketing of PABA-free products, primarily containing benzophenones as an alternative. Subsequently, reports of photoallergic reactions to benzophenone increased.…”

Contact allergy/photo allergy to glyceryl PABA and benzocaine

“…Photo-patch tests were not performed. Satulsky (1950) reported a patient with a photosensitivity eruption due to glyceryl PABA. Patch tests were negative, but photo-patch tests were positive.…”

Photocontact Dermatitis from P-Aminobenzoic Acid

“…The responsible components of the agents were digalloyl trioleate [10] and glyceryl /;-aminobenzoate [2,11], It has been described in textbooks and review articles that PABA can cause photoallergic reactions. Nevertheless, we, as well as W illis and K ligm an [12], cannot find any original documentation of this knowledge.…”