Photoresponsive hydrogel microvalve activated by bacteriorhodopsin proton pumps

Al-Aribe, Khaled M.; Knopf, George K.

doi:10.1117/12.848769

Cited by 14 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to some special properties, many materials and creatures are used to actuate microvalves. Actuation mechanisms of phase change materials are discussed, including polymer (hydrogel [93][94][95][96], sol-gel [97]), paraffin [98][99][100][101][102][103], alloy (low melting point alloy [104][105][106] and shape memory alloy [107][108][109][110][111][112]). Compared with the traditional mechanically active microvalves, these phase change microvalves are relatively new and cheap.…”

Section: Materials and Biology Properties Actuationmentioning

confidence: 99%

“…The microvalves based on light actuation are also referred to as photoresponsive microvalves [94]. The light sources are divided into visible light and invisible light.…”

Section: Light Actuationmentioning

confidence: 99%

“…Upon irradiation, each bR molecule worked as a proton pump to transports hydrogen ions through a transmembrane ion channel. The results revealed that an 8 µm gap of microchannel could be closed by the valve under a focused light beam [93,94]. Benito-Lopez et al showed four types of ionogels (ionic liquid polymer gels) applied to light actuated valves.…”

Section: Light Actuationmentioning

confidence: 99%

See 2 more Smart Citations

Actuation Mechanism of Microvalves: A Review

Qian

Hou

2020

Micromachines

View full text Add to dashboard Cite

The microvalve is one of the most important components in microfluidics. With decades of development, the microvalve has been widely used in many industries such as life science, chemical engineering, chip, and so forth. This paper presents a comprehensive review of the progress made over the past years about microvalves based on different actuation mechanisms. According to driving sources, plenty of actuation mechanisms are developed and adopted in microvalves, including electricity, magnetism, gas, material and creature, surface acoustic wave, and so on. Although there are currently a variety of microvalves, problems such as leakage, low precision, poor reliability, high energy consumption, and high cost still exist. Problems deserving to be further addressed are suggested, aimed at materials, fabrication methods, controlling performances, flow characteristics, and applications.

show abstract

Section: Materials and Biology Properties Actuationmentioning

confidence: 99%

“…The microvalves based on light actuation are also referred to as photoresponsive microvalves [94]. The light sources are divided into visible light and invisible light.…”

Section: Light Actuationmentioning

confidence: 99%

Section: Light Actuationmentioning

confidence: 99%

See 1 more Smart Citation

Actuation Mechanism of Microvalves: A Review

Qian

Hou

2020

Micromachines

View full text Add to dashboard Cite

show abstract

“…The super hydrophobicity of the lotus flowers has been mimicked to design facade paints, tiles, self-cleaning glasses and surfaces where hydro-degradation occurs 1 , 2 . Biohybrid systems such as microfluidic devices have been developed by inspiration from the fluid transportation of plants with the light energy stored in them through photosynthesis 3 , 4 . The transportation of fluids and waters in the plants is also taken as inspiration in textile fabrications.…”

Section: Introductionmentioning

confidence: 99%

3D printable biomimetic rod with superior buckling resistance designed by machine learning

Challapalli

2020

Sci Rep

View full text Add to dashboard Cite

Our mother nature has been providing human beings with numerous resources to inspire from, in building a finer life. Particularly in structural design, plenteous notions are being drawn from nature in enhancing the structural capacity as well as the appearance of the structures. Here plant stems, roots and various other structures available in nature that exhibit better buckling resistance are mimicked and modeled by finite element analysis to create a training database. The finite element analysis is validated by uniaxial compression to buckling of 3D printed biomimetic rods using a polymeric ink. After feature identification, forward design and data filtering are conducted by machine learning to optimize the biomimetic rods. The results show that the machine learning designed rods have 150% better buckling resistance than all the rods in the training database, i.e., better than the nature’s counterparts. It is expected that this study opens up a new opportunity to design engineering rods or columns with superior buckling resistance such as in bridges, buildings, and truss structures.

show abstract

Fabrication of an optically driven pH gradient generator based on self-assembled proton pumps

Al-Aribe

Knopf

Bassi

2011

Microfluid Nanofluid

Self Cite

View full text Add to dashboard Cite

Optically manipulating the local pH of a target solution in a microchannel, or reservoir, provides a mechanism for activating and controlling a variety of biological and chemical processes on Lab-on-a-Chip (LOC) devices and micro-total analysis systems (l-TAS). A microscale pH gradient generator that exploits the lightactivated molecular proton pumps found in the purple membranes (PM) of bacteriorhodopsin is described in this paper. The photo-electro-chemical transducer is an ultrathin layer (*13 nm) of oriented PM patches self-assembled on an Au-coated porous substrate. A biotin labeling and streptavidin molecular recognition technique is used to ensure that the extracellular side of all PM patches is attached to the porous substrate enabling unidirectional and efficient transport of ions across the transducer surface. The photo-induced proton pumps generate a flow of ions that produce a measurable change in pH between the separated solutions. The self-assembly procedure is experimentally quantified based on the capacitance characteristics of the bR membranes. The investigation confirms that the transducer is covered with the bR proton pumps at a mass density of 2.33 ng/cm 2 . Experimental tests also show that the proposed transducer can repeatedly generate pH gradients as high as 0.42 and absolute voltage differences as high as 25 mV when illuminated by an 18 mW, 568 nm light source. Furthermore, the DpH is observed to be nonlinear with respect to light intensity and exposure time. The DpH of the target solution is sufficient to cause a phenolphthalein indicator dye to change color or an ionic hydrogel micro-valve to expand.

show abstract

Photoresponsive hydrogel microvalve activated by bacteriorhodopsin proton pumps

Cited by 14 publications

References 0 publications

Actuation Mechanism of Microvalves: A Review

Actuation Mechanism of Microvalves: A Review

3D printable biomimetic rod with superior buckling resistance designed by machine learning

Fabrication of an optically driven pH gradient generator based on self-assembled proton pumps

Contact Info

Product

Resources

About