Photorefractive keratectomy in african americans including those with known dermatologic keloid formation

Tanzer, David J.; Isfahani, Amir; Schallhorn, Steven C.; LaBree, Laurie; McDonnell, Peter J.

doi:10.1016/s0002-9394(98)00204-9

Cited by 18 publications

(7 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tanzer et al, studying PRK in African American patients, including those known to be keloid formers, found no increased risk for haze or regression (9) . They also found that African Americans may have an excellent visual outcome following PRK and history of keloid formation does not appear to have an adverse effect on the outcome.…”

Section: Discussionmentioning

confidence: 98%

Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Cresta¹,

Ma²,

LaBree³

et al. 2002

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

Arq Bras Oftalmol 2002;65: Purpose: To examine the effect of patient race on clinical outcomes following excimer laser surgery for myopia and myopic astigmatism. Methods: A total of 116 eyes from Caucasian patients, 16 eyes from Asian patients and 16 eyes from Hispanic patients who underwent PRK were evaluated retrospectively. PRK procedures were performed by the same surgeon using a 193 nm argon-fluoride excimer laser (VISX) with 160 mJ/ cm 2 fluence and a 6.5 Hz repetition rate at the Doheny Eye Institute. During 6 months of follow-up, changes in the uncorrected visual acuity (UCVA), refraction and spectacle-corrected visual acuity (SCVA) were evaluated. Pairwise comparisons between races were performed for age, sphere and cylinder using independent sample t tests, while UCVA and SCVA were compared using Fisher's exact tests. The accepted level of significance for all tests was α = 0.05/3 = 0.0167. Results: The only differences found were between the Asian versus Caucasian groups related to the spectaclecorrected visual acuity of 20/15 (p=0.01) and in the Asian versus Hispanic groups related to the mean cylinder (p=0.04) at 3 months postoperatively. The comparison of the mean cylinder showed a statistically significant difference between the Asian versus Hispanic groups at 6 months postoperatively (p=0.04). After 6 months, 72.7% of the eyes in the Asian group, 85.7% of the eyes in the Hispanic group and 87.1% of the eyes in the Caucasian group had uncorrected visual acuity of 20/40 or better and the mean sphere and cylinder (±SD) were: -0.55 (± 0.88) and 0.97 (± 0.79); -0.75 (± 1.24) and 0.40 (± 0.45); -1.21 (± 2.55) and 0.75 (± 0.89), respectively. Conclusion: In this study, there were no statistically significant differences between the three race groups related to the final visual outcome following photorefractive keratectomy. These preliminary results suggest that the clinical outcomes of PRK are not significantly affected by patient race. Larger populations and longer-term studies are needed to definitely determine whether racial differences exist.

show abstract

Section: Discussionmentioning

confidence: 98%

Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Cresta¹,

Ma²,

LaBree³

et al. 2002

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

show abstract

“…There is, however, no consensus on the safety and efficacy guidelines of PRK or LASIK for patients with dermatologic keloids. Tanzer et al [2] have reported that a history of keloid formation does not appear to adversely affect the outcomes of PRK. Similarly, Cobo-Soriano et al [3] reported no difference in the anatomical or functional results following LASIK between patients with dermatologic keloids and those without.…”

Section: Discussionmentioning

confidence: 99%

“…The results of photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK) in patients with dermatologic keloids have been contradictory and could potentially be misleading [2-5]. Epipolis (Epi)-LASIK is an alternative surface ablation procedure for refractive surgery [6].…”

mentioning

confidence: 99%

Conventional Epi-LASIK and Lamellar Epithelial Debridement in Myopic Patients with Dermatologic Keloids

Lee

Youm

Choi

2011

Korean J Ophthalmol

View full text Add to dashboard Cite

We report the outcome of conventional epipolis laser in situ keratomileusis (Epi-LASIK, flap-on) and lamellar epithelial debridement (LED; Epi-LASIK, flap-off) in myopic patients with dermatologic keloids. Three patients, who were all noted to be susceptible to keloid scarring, received conventional Epi-LASIK in their right eyes and LED in their left eyes. The patients were followed-up for 6 to 21 months after their surgeries, and the outcomes were then evaluated. In case 1, the preoperative spherical equivalent (SE) was -6.5 diopters (D) in the right eye (OD) and -6.25 D in the left eye (OS). At 21 months postoperatively, the uncorrected visual acuity (UCVA) was 20 / 12.5 in both eyes. In case 2, the preoperative SE was -5.25 (OD) / -6.00 (OS). After six months, the postoperative UCVA was 20 / 12.5 in both eyes. In case 3, the preoperative SE was -4.5 (OD) / -2.0 (OS). The UCVA at the six-month follow-up was 20 / 12.5 in both eyes. No adverse events, including corneal haze, occurred in any of the patients. All three of our patients reported excellent visual outcomes following both conventional Epi-LASIK and LED, despite their histories of keloid formation. The present cases suggest that both Epi-LASIK and LED may be safe and effective techniques for myopic patients with dermatologic keloids.

show abstract

“…Tanzer et al ., showed good refractive outcome of PRK in six eyes in African American patients with history of keloid formation. No serious complication was reported and no difference in postoperative UCVA or best corrected visual acuity (BSCVA) was found between patients with dermatologic keloid and non-keloid formation 71. Artola et al ., reported a retrospective study of five patients (ten eyes) with history of keloid formation 72.…”

Section: Dermatologic Keloidmentioning

confidence: 95%

Refractive surgery in systemic and autoimmune disease

Alkharashi

Bower

Stark

et al. 2014

Middle East Afr J Ophthalmol

View full text Add to dashboard Cite

Patients with underlying systemic disease represent challenging treatment dilemma to the refractive surgeon. The refractive error in this patient population is accompanied by a systemic disease that may have an ocular or even a corneal component. The literature is rather sparse about the use of laser refractive surgery (LRS) and such procedure is not approved by the United States Food and Drug Administration (FDA) in this patient population. Patients with collagen vascular disease, diabetes mellitus (DM), allergic and atopic disease, or human immunodeficiency virus (HIV) are never ideal for LRS. Patients with uncontrolled systemic disease or ocular involvement of the disease should not undergo LRS. However, a patient with well-controlled and mild disease, no ocular involvement, and not on multidrug regimen may be a suitable candidate if they meet stringent criteria. There is a need for a large, multicenter, controlled trial to address the safety and efficacy of LRS in patients with systemic disease before such technology can be widely adopted by the refractive surgery community.

show abstract

Photorefractive keratectomy in african americans including those with known dermatologic keloid formation

Cited by 18 publications

References 14 publications

Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Influence of patient race on the outcome of photorefractive keratectomy for myopia correction

Conventional Epi-LASIK and Lamellar Epithelial Debridement in Myopic Patients with Dermatologic Keloids

Refractive surgery in systemic and autoimmune disease

Contact Info

Product

Resources

About