Photoperiodic Regulation of Reproductive Development in White-footed Mice (Peromyscus leucopus)

Johnston, Phyllis G.; Zucker, Irving H.

doi:10.1095/biolreprod22.4.983

Cited by 60 publications

(33 citation statements)

References 11 publications

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“…Indeed, data from several laboratories suggest that the reproductive system of the male sheep begins to respond to photoperiod after puberty (Alberto & Colas, 1976;Howies et al, 1980;Lincoln & Almeida, 1981), as is true for the developing male golden hamster (Sisk & Turek, 1983). In other mammals, however, the timing of puberty in the male is very sensitive to photoperiodic manipulation (field vole: Lecyk, 1962; white-footed mouse; Johnston & Zucker, 1980;Djungarian hamster: Yellon & Goldman, 1984).…”

Section: Resultsmentioning

confidence: 99%

Control of gonadotrophin secretion during the pubertal and seasonal transitions in the male sheep

Olster

Foster²

1988

Reproduction

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Summary. Castration of spring-born, male Suffolk lambs at 2 weeks of age resulted in a rapid increase in gonadotrophin secretion. LH pulse frequency stabilized by 6 The results reveal fundamental differences between the regulation of gonadotrophin secretion in ram lambs and adults. The pubertal decrease in response to inhibition by steroids, which is not coincident with a steroid-independent increase in gonadotrophin secretion, may play a key role in increasing gonadotrophin secretion to initiate gonadal activity in the spring. The post-pubertal ram also exhibits the first signs of the seasonal resumption of reproductive activity in the spring. However, it is not until the autumn that a decrease in response to inhibitory feedback by steroids occurs, in concert with a steroid-independent increase in gonadotrophin release. Therefore, in the sexually mature ram, rather than stimulating the initial springtime recovery of gonadal function, these two mechanisms may act in concert to achieve gonadotrophin concentrations and/or patterns necessary to optimize reproductive competence in the autumn.

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Section: Resultsmentioning

confidence: 99%

Control of gonadotrophin secretion during the pubertal and seasonal transitions in the male sheep

Olster

Foster²

1988

Reproduction

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“…Indeed, some of the first evidence that melatonin drives seasonal gonad regression in small mammals comes from this species (Whitaker 1936). Simple SD exposure (Pyter et al 2005a) or administration of melatonin in LD via timed injections (Hall et al 1985) or subcutaneous (Johnston et al 1980a) or central (i.e., anterior hypothalamus) implants (Glass et al 1987) induce gonad regression in white-footed mice (Johnston et al 1980a;Johnston et al 1980b). As with other seasonal breeders, melatonin-induced gonad regression occurs when GnRH release from the hypothalamus is down-regulated (Glass et al 1981;Glass et al 1987), eliminating tonic LH stimulation of the gonads (Glass et al 1988) and ultimately apoptosis of the testes (Young et al 2000).…”

Section: Discussionmentioning

confidence: 99%

“…We assessed effects of 6-MBOA on reproductive parameters and DTH in long-day breeding whitefooted mice. This species was chosen because individuals i) exhibit seasonal changes in immune activity and reproductive capacity (Johnston et al 1980b;Pyter et al 2005b), ii) some of these changes are mediated by melatonin (Johnston et al 1980a;Glass et al 1988), and iii) individuals consume a variety of foods in the wild, including plants (King 1968). Other species known to be sensitive reproductively to 6-MBOA have not been as well characterized.…”

Section: Introductionmentioning

confidence: 99%

6-MBOA affects testis size, but not delayed-type hypersensitivity, in white-footed mice (Peromyscus leucopus)

Martin

Johnson

Hutch

et al. 2008

Comparative Biochemistry and Physiology Part A: Molecular &

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Many rodents use day length to time reproduction to occur when resources are abundant, but some species also use supplementary environmental cues. One supplementary cue is the plant-derived compound, 6-methoxy-2-benzoxazolinone (6-MBOA). Most rodents grow their gonads in response to 6-MBOA in their diets, but it is presently unknown whether they also use 6-MBOA to adjust other aspects of physiology, specifically their immune systems. 6-MBOA is structurally similar to melatonin, and seasonal changes in rodent immune activities are often mediated by melatonin. We therefore predicted that white-footed mice (Peromyscus leucopus), which breed seasonally and are reproductively sensitive to melatonin, would adjust their immune systems when fed 6-MBOA. 6-MBOA treated mice in long day lengths regressed their testes to a greater extent than mice fed a standard diet, or mice kept in short day lengths and fed 6-MBOA or a standard diet. One type of immune activity (delayed-type hypersensitivity) was not affected by 6-MBOA, however, although responses were greater in short versus long day mice. In sum, P. leucopus responded reproductively to 6-MBOA, although differently than other species; immune activity was unaffected. Other aspects of the immune system, especially in herbivorous rodents, may be affected by 6-MBOA and thus warrant further study.

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“…Several investigations have demonstrated that long photoperiods accelerate and short photoperiods retard puberty in two species of cricetid mice of the genus Peromyscus (Johnston & Zucker, 1980;Petterborg & Reiter, 1980;Whitsett & Miller, 1982).…”

Section: Introductionmentioning

confidence: 99%

Effect of transitional photoperiods on testicular development and puberty in male deer mice (Peromyscus maniculatus)

Whitsett¹,

Noden²,

Cherry³

et al. 1984

Reproduction

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Photoperiodic Regulation of Reproductive Development in White-footed Mice (Peromyscus leucopus)

Cited by 60 publications

References 11 publications

Control of gonadotrophin secretion during the pubertal and seasonal transitions in the male sheep

Control of gonadotrophin secretion during the pubertal and seasonal transitions in the male sheep

6-MBOA affects testis size, but not delayed-type hypersensitivity, in white-footed mice (Peromyscus leucopus)

Effect of transitional photoperiods on testicular development and puberty in male deer mice (Peromyscus maniculatus)

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