We consider the resonant optical force acting on a pair of transparent microspheres by the excitation of the Morphology Dependent Resonance (MDR). The bonding and anti-bonding modes of the MDR correspond to strong attractions and repulsions respectively. The dependence of the force on separation and the role of absorption are discussed. At resonance, the force can be enhanced by orders of magnitude so that it will dominate over other relevant forces. We find that a stable binding configuration can be induced by the resonant optical force.Optical forces are useful in the manipulation of ultra-fine particles and mesoscopic systems, and the development is rather astounding in the last three decades. The most well known types of the optical forces are the radiation pressure and the optical gradient force. There is also an inter-particle optical force, induced by the multiple scattering of light.1-7 We present here an interesting type of resonant inter-particle force. We will see that the tuning of the incident light frequency to the Morphology Dependent Resonance (MDR) of a cluster of transparent microspheres would induce a strong resonant optical force (MDR-force) between the spheres. The MDR of a pair of spheres had been observed in fluorescent 8, 9 and lasing 10 experiments. Here we study theoretically the force induced by such resonances. We will see that the MDR-induced force, derived from the coherent coupling of the whispering gallery modes (WGM's), is a strong short ranged force that can be attractive or repulsive depending on whether the bonding mode (BM) or the anti-bonding mode (ABM) is excited. The strength of the optical forces can be enhanced by orders of magnitude when a MDR is excited. As microsphere cavities are emerging as an alternative to the photonic crystal in controlling light, 8-10 the MDR-force may be deployed for the manipulation of a microsphere cluster.In this paper, we calculate the electromagnetic (EM) forces acting on microspheres when WGM's or MDR's are excited. The optical force acting on a microsphere can be computed via a surface integral of the Maxwell stress tensor, ↔ T , over the sphere's surface. The microspheres cannot respond to the high frequency component of the time varying optical force, so we calculate the time-averaged force < T is computed by the multiple scattering theory, 1, 11 which expands the fields in vector spherical harmonics. This formalism is quite possibly the most accurate method that can be applied. It is in principle exact, and the numerical convergence is being controlled by the maximum angular momentum (L max ) used in the expansion. The calculation for the resonance of dielectric microspheres near contact requires a high L max , 12 which is chosen so that further increase in L max does not change the value of the calculated force. In most of the calculations, the size parameter (kR) is between 28 and 29, and L max =63 was used. We adopt the Generalized Minimal Residual iterative solver (GMRES) for the linear system of equations.13 In the following, th...