Photoluminescent Enzymatic Sensor Based on Nanoporous Anodic Alumina

Santos, Abel; Macías, Gerard; Ferré‐Borrull, Josep; Pallarès, Josep; Marsal, Lluís F.

doi:10.1021/am300648j

Cited by 75 publications

(59 citation statements)

References 29 publications

(46 reference statements)

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“…The authors examined the effect of PAA nanotopography with different pore sizes (20,100 and 200 nm in diameter) on osteogenic differentiation and drug eluting properties. Stem cells (W20-17, mouse bone marrow stromal cells) were used in the cell cultures.…”

Section: Cell Growthmentioning

confidence: 99%

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Mesoporous alumina as a biomaterial for biomedical applications

Xifré-Pérez

Ferre-Borull

Pallarès

et al. 2015

Open Material Sciences

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Porous anodic alumina (PAA) is a biomaterial based on a cost-effective electrochemical anodization of pure aluminum with unique geometrical properties, i.e., self-ordering hexagonal pore distribution, tunable pore diameters and interpore distances, and uniformity of the pores in the vertical direction (nanochannels). These remarkable properties have found important applications in several fields such as energy storage, optics, photonics, magnetism, catalysis and, in particular, in the biomedicine field. In this work, we review the current state of research and key issues on cell culture and implants, drug delivery systems with complex release profiles and specific action, and high efficiency and sensitivity biosensors with different biosensing mechanisms, all of them based on PAA. The biocompatibility, morphology of the surface, nanoestructural engineering in-depth, surface functionalization and coatings are discussed and analyzed in detail.

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Section: Cell Growthmentioning

confidence: 99%

“…A selective and highly sensitive enzymatic photoluminescent biosensor is presented in ref. [100]. It highlights for its accurate detection and quantification of the analyzed sample, trypsin.…”

Section: Biosensingmentioning

confidence: 99%

Mesoporous alumina as a biomaterial for biomedical applications

Xifré-Pérez

Ferre-Borull

Pallarès

et al. 2015

Open Material Sciences

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“…A selective and highly sensitive enzymatic PL biosensor is presented in [134]. It highlights for its accurate detection and quantification of the analyzed sample, trypsin.…”

Section: Photoluminescence-based Applications Of Porous Anodic Aluminmentioning

confidence: 99%

Optical Properties of Nanoporous Anodic Alumina and Derived Applications

et al. 2015

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Inexpensive formation of periodically ordered structures with periodicities and feature sizes lower than 100 nm has triggered a vast amount or research in recent years. Of particular interest in nanotechnology is the nanoporous alumina, which can be produced with a self-organized arrangement of pores in the adequate anodization conditions. Most of the interest of this material is based in its outstanding physical and chemical and properties, and more specifically in its optical properties. The interaction of light with the nanostructured porous alumina gives rise to a wealth of optical properties that have their interest both in research level and also in application. In this work we aim at giving an extensive review of the published research on the optical properties of nanoporous alumina. The review will account for the different studied optical properties of this material such as the existence of a photonic stop band originated from its quasi-random nanostructure, the interferometric and light guiding properties that can be applied to biosensing, the structure nanoengineering to achieve more complex photonic behaviour such as distributed-Bragg reflectors or rugate filters, and the photoluminescence properties. In a second part, a summary of the different applications proposed on the basis of these properties, such as in biotechnology or energy will be given. IntroductionAmong the different features and properties of porous anodic alumina (p-AAO), its optical properties are of special interest and have been the subject of very intensive research. The interaction of light with p-AAO can be analyzed from different points of view: the material interaction, the porous structure interaction or the relation of geometrical features of the nanostructure (periodicity or quasi-periodicity, distance

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“…Due to the surface chemistry of anodic alumina, the pore walls are being functionalized, and numerous sensors are being formed. The detection of glucose oxidase [113], thrombin [55], DNA [211,260,263], surface active agents [123], Ara h1 peanut protein [231], trypsin [222], and urea [281] is enabled. Moreover, application Özt€ urk et al [194] Fig .…”

Section: Applications Of Anodic Aluminum Oxidementioning

confidence: 99%

Nanoporous Anodic Aluminum Oxide: Fabrication, Characterization, and Applications

Stępniowski

Bojar

2015

Handbook of Nanoelectrochemistry

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Anodic aluminum oxide (AAO) consists of parallel pores arranged in a honeycomb-like array. Since a two-step self-organized approach in anodic alumina fabrication was invented, tremendous attention was paid to this material. Structural features of anodic alumina, like pore diameter, interpore distance, and nanoporous oxide thickness, can be fully controlled by operating conditions, including type, concentration and temperature of the electrolyte, applied voltage, and duration of the anodization process. Moreover, these operating conditions have also a major impact on the nanoporous array arrangement. Quantitative arrangement analysis methods employing fast Fourier transforms have been developed to assess the nanopores' arrangement. The most frequent application of the anodic aluminum oxide is a template-assisted fabrication of nanostructures. Templates made of the AAO are being successfully applied in fabrication of nanowires, nanotubes, and nanodots by using diversity of techniques, including electrochemical deposition, physical and chemical vapor deposition, sol-gel techniques, etc. Due to the size of obtained nanostructures, magnetic, electric, piezoelectric, luminescent, and catalytic properties of the deposited materials can be significantly improved. Thus, control of the nanopores' structural features and arrangement is crucial for AAO applications in nanotechnology.

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Photoluminescent Enzymatic Sensor Based on Nanoporous Anodic Alumina

Cited by 75 publications

References 29 publications

Mesoporous alumina as a biomaterial for biomedical applications

Mesoporous alumina as a biomaterial for biomedical applications

Optical Properties of Nanoporous Anodic Alumina and Derived Applications

Nanoporous Anodic Aluminum Oxide: Fabrication, Characterization, and Applications

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