Photoluminescent and superparamagnetic reduced graphene oxide–iron oxide quantum dots for dual-modality imaging, drug delivery and photothermal therapy

Justin, Richard; Tao, Ke; Román, Sabiniano; Chen, Dexin; Xu, Yawen; Geng, Xiangshuai; Ross, I. M.; Grant, Richard T.; Pearson, Andrew J.; Zhou, Guangdong; MacNeil, Sheila; Kim, Sun; Chen, Biqiong

doi:10.1016/j.carbon.2015.06.070

Cited by 108 publications

(78 citation statements)

References 106 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The addition of silica shell created another barrier to prevent the unwanted release of the drug during transportation. Apart from SiO 2 , Fe 3 O 4 QDs/rGO composite has been shown to be capable of releasing the anesthetic lidocaine hydrochloride (LH) after 8 h, with little toxicity up to 50 µg mL −1 . Although major advancements have been seen in this field, more studies on the immune response during the residence time of the carrier‐drug conjugate, the toxicity of carrier materials and their possible decomposition products are still needed.…”

Section: Functional Applications Of Iron Oxide‐based Nanoarchitecturesmentioning

confidence: 99%

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

et al. 2019

View full text Add to dashboard Cite

Iron oxide nanoarchitectures with distinct morphologies from 1D to 3D have been developed using various wet chemical methods. They have been employed for a wide range of applications, including energy storage, biomedical, and environmental applications. The functional properties of iron oxide nanoarchitectures depend on the size, shape, composition, magnetic properties, and surface modification. To overcome the limitations of pure iron oxide nanostructures, hybridizations with various inorganic materials (e.g., silica, metals, metal oxides) and carbon‐based materials have been proposed. Herein, the recent advances in the preparation of various iron oxide nanoarchitectures are reviewed along with their functional applications in energy storage, biomedical, and environmental fields. Finally, the effects of various parameters on the functional performance of iron oxide nanostructures for these applications are summarized and the trends and future outlook on the development of iron oxide nanoarchitectures for these applications are also given.

show abstract

Section: Functional Applications Of Iron Oxide‐based Nanoarchitecturesmentioning

confidence: 99%

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Such novel hybrid NCs will be suitable for delivering nanocarriers to the tumor sites for imaging, whereas the NCs optical feature can be used as photothermal therapy agents to kill cancer cells efficiently [28][29][30]. erefore, the NCs offering both optical and magnetic capabilities may provide an interesting approach for the future medical treatments.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, Optical, and Magnetic Properties of Graphene Quantum Dots and Iron Oxide Nanocomposites

Sajjad

Makarov

Sultan

et al. 2018

Advances in Materials Science and Engineering

View full text Add to dashboard Cite

e combination of nanomaterial graphene quantum dots (GQDs) with magnetic nanoparticles offers a unique set of optical and magnetic properties for future energy and medical applications. We report on the synthesis and engineering of GQDs and iron oxide (Fe 3 O 4 ) nanocomposites (NCs) by using a pulsed laser discharge technique. High-resolution transmission electron microscopy (HRTEM) images showed a high yield of pure GQDs with 2-10 nm diameter. e hexagonal structures and lattice fringes associated with the C-C bond in GQDs were clearly identifiable. e structural and optical changes in GQDs and GQDsFe 3 O 4 NC samples induced by UV light were investigated by the absorption and emission spectroscopy over the deep UV-visible spectral range. e photoluminescence spectra have shown subband π→π * transitions in GQDs-Fe 3 O 4 NC. Magnetic properties of the GQDs-Fe 3 O 4 NC samples have shown room temperature ferromagnetism induced by pure Fe 3 O 4 nanoparticles and from the substantial spin polarized edges of GQD nanoparticles. It is concluded that the observed optical and magnetic properties could be further tailored in the studied nanocomposites for prospective medical applications.

show abstract

“…Apart from Gd, IO can also be combined with QDs to construct IO‐QD hybrids through doping or coencapsulation, and the resulting probe combines the intriguing aspects of both individual NPs . A FI/MRI dual‐modality probe utilizing IO‐QDs has been widely described in various biomedical applications, such as subcellular labeling and disease detection .…”

Section: Fi and Mrimentioning

confidence: 99%

Biomedical Applications of Fluorescent and Magnetic Resonance Imaging Dual‐Modality Probes

Ruan

et al. 2018

ChemBioChem

View full text Add to dashboard Cite

Molecular imaging plays a critical role in biomedical research. The combination of different modalities can generate complementary information and provide synergistic advantages over single modality alone. Noninvasive and nonradioactive fluorescent imaging (FI)/magnetic resonance imaging (MRI) dualmodality probes fuse the high sensitivity of FI and the high temporal and spatial resolution and deep-tissue penetration of MRI, and their increasing applications have been reported in biomedical research and clinical practices, including cell labeling, enzyme activity measurement, tumor diagnosis and therapy, and anatomical localization and real-time assessment during surgery.

show abstract

Photoluminescent and superparamagnetic reduced graphene oxide–iron oxide quantum dots for dual-modality imaging, drug delivery and photothermal therapy

Cited by 108 publications

References 106 publications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

Synthesis, Optical, and Magnetic Properties of Graphene Quantum Dots and Iron Oxide Nanocomposites

Biomedical Applications of Fluorescent and Magnetic Resonance Imaging Dual‐Modality Probes

Contact Info

Product

Resources

About