Photoinactivation of non-tuberculous mycobacteria using Zn-phthalocyanine loaded into liposomes

Miretti, Mariana; Juri, Leticia; Peralta, Alejandra; Cosiansi, María C.; Baumgartner, María T.; Tempesti, Tomás Cristian

doi:10.1016/j.tube.2022.102247

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…In addition to porphyrins, especially cationic ones, which are by far the most prevalent exogenous PSs in studies on mycobacteria, MB has also been shown to be effective in PDI against M. fortuitum [156], as well as Zn(II) phthalocyanine, which was used in liposomes against M. fortuitum and M. chelonae [157].…”

Section: Mycobacteriamentioning

confidence: 99%

Photodynamic Inactivation of Opportunistic Premise Plumbing Pathogens and Their Biofilms

Mušković,

Gobin,

Malatesti

2023

Processes

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Opportunistic premise plumbing pathogens (OPPPs) form a group of microorganisms that normally live in water supply systems and have adapted especially well to the conditions in premise plumbing systems, and as such pose a threat to human health. Since the beginning of the 21st century, this threat has been escalating, and it is becoming increasingly evident that current water disinfection methods fall short in effectively controlling these pathogens. In researching new approaches to this emergency, phototherapy looks promising, especially one that combines photosensitizers, light, and oxygen, which is known as photodynamic inactivation (PDI). This review describes the main characteristics of the recognized (Pseudomonas aeruginosa, Legionella pneumophila, and Mycobacterium avium) and most important emerging OPPPs, and it offers a brief overview of current disinfection methods and their limitations in the fight against OPPPs. The principle and outcomes of PDI with endogenous and, in particular, exogenous photosensitizers are then explained and described through representative examples of PDI on recognized and emerging OPPPs and their biofilms. Finally, the prospects and future directions of PDI research in water disinfection and control of OPPPs are discussed.

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Section: Mycobacteriamentioning

confidence: 99%