Photoelectrochemical impedance spectroscopy sensor for cloxacillin based on tetrabutylammonium octamolybdate

Najlaoui, D.; Echabaane, M.; Khelifa, Arbia Ben; Rouis, A.; Ouada, H. Ben

doi:10.1007/s10008-019-04440-0

Cited by 14 publications

(5 citation statements)

References 74 publications

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“…As expected, the data mirror the CV results. The charge transfer resistance, R ct , was calculated by the equivalent circuit shown in Figure B, which is based on modified electrode equivalent circuits for electrodes with surface modification. − The R ct values represented by the bar chart in Figure B correspond to R3 in the equivalent circuit, and the average percent error of the fit was less than 5% across all conditions (Table S1). The R ct increases upon the addition of streptavidin compared to the control of phosphate buffered saline (PBS) yet decreases substantially when the streptavidinated antibody is bound instead.…”

Section: Resultsmentioning

confidence: 99%

Surface Modification of Thermoplastic Electrodes for Biosensing Applications via Copper-Catalyzed Click Chemistry

Martinez,

Leroux,

Hapiot

et al. 2023

ACS Appl. Mater. Interfaces

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Cu(I)-catalyzed 1,3-dipolar cycloaddition (CuAAC), also known as click chemistry, has been demonstrated to be highly robust while providing versatile surface chemistry. One specific application is biosensor fabrication. Recently, we developed thermoplastic electrodes (TPEs) as an alternative to traditional carbon composite electrodes in terms of cost, performance, and robustness. However, their applications in biosensing are currently limited due to a lack of facile methods for electrode modification. Here, we demonstrate the feasibility of using CuAAC following the diazonium grafting of TPEs to take advantage of two powerful technologies for developing a customizable and versatile biosensing platform. After a stepwise characterization of the electrode modification procedures was performed, electrodes were modified with model affinity reagents. Streptavidin and streptavidin-conjugated IgG antibodies were successfully immobilized on the TPE surface, as confirmed by electrochemical impedance spectroscopy and X-ray photoelectron spectroscopy.

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Section: Resultsmentioning

confidence: 99%

Surface Modification of Thermoplastic Electrodes for Biosensing Applications via Copper-Catalyzed Click Chemistry

Martinez,

Leroux,

Hapiot

et al. 2023

ACS Appl. Mater. Interfaces

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“…38 EIS can characterize the surface properties of electrodes, and then examine the electron transfer efficiency of electrodes in solution to study the conductivity of electrode modification materials. 39 As shown in Fig. 3B, an equivalent circuit model was fitted to the structure formed by the combination of GPC3apt and GPC3 will inhibit the transfer of electrons.…”

Section: Resultsmentioning

confidence: 99%

An Ultrasensitive Glypican‑3 Electrochemical Aptasensor Based on Reduced Graphene Oxide-Carboxymethylchitosan-Hemin/Palladium Nanoparticles

Li¹,

Li²,

Cao³

et al. 2022

J. Electrochem. Soc.

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Glypican-3 (GPC3) is a serum marker for hepatocellular carcinoma (HCC) and has excellent specificity and sensitivity. Herein, the construction of an electrochemical aptasensor based on reduced graphene oxide-carboxymethyl chitosan-hemin-palladium nanoparticles (RGO-CMCS-Hemin/Pd NPs) and GPC3 aptamer (GPC3apt) has the function of GPC3 identification and analysis. RGO-CMCS-Hemin/Pd NPs has excellent biocompatibility, large specific surface area, and good electrical conductivity, which is not only useful as an advanced sensing material to modify the electrode surface to reduce the resistance and increase the signal amplitude, but also used as an electroactive substance to provide electrical signals. GPC3apt as a biometric element gives the aptasensor good specificity and sensitivity. The GPC3apt can combine with GPC3 and form GPC3-aptamer conjugation, which increases the electron transfer impedance and changes the electrical signal. Under optimum conditions, the aptasensor had a good linear relationship with the GPC3 concentration in the range of 1.0-100.0 ng/mL with R2 of 0.9573. The lower limit of detection was 1.0 ng/mL. When the aptasensor was applied to GPC3 detection in human serum samples, the recovery was 93.73%-118.83%. In addition, the GPC3 aptasensor has excellent specificity, reproducibility, and stability, which can be applied in the clinical detection of GPC3.

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“…For sensor measurements, the potential polarization has a vast in uence on impedimetric sensor response since it leads to an improved sensitivity for the recognition of the target analyte [32]. Fig.…”

Section: Characterization Of the Functionalized Gcementioning

confidence: 99%

Development of an impedimetric sensor based on carbon dots and chitosan nanocomposite modified electrode for Cu(II) detection in water

Echabaane

Hfaiedh

Smiri

et al. 2021

J Solid State Electrochem

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The fast and sensitive detection of copper ions would be essential for water monitoring. Herein, we report a novel development of impedimetric sensor based on carbon dots/chitosan nanocomposite. Carbon dots (CDs) were synthesized by simple heating of acidic aqueous solution of glucose. The CDs were characterized by TEM, FTIR, XRD, UV-visible, and PL. These measurements revealed that the CDs possess a mean size of 3.2 nm, graphitic structure with carboxyl and hydroxyl groups on the surface, and show particular optical properties. A glassy carbon electrode (GCE) was modified with a carbon dots/chitosan (CHITO) nanocomposite, and was characterized by transmission electron microscopy and electrochemical impedance spectroscopy (EIS). The CDs-CHITO/GCE electrode exhibits large surface area, good conductivity lm, and charge transfer at interface lm/electrolyte. The proposed impedimetric sensor exhibits a linear response to Cu(II) over 10 -9 M to 10 -5 M rang with a limit of detection at about 5×10 -10 M. In addition, the sensor shows good selectivity toward Cu(II) ions, which is less than 5 %.Therefore, the as-developed impedimetric sensor exhibits good reproducibility, stability, selectivity, and a low limit of detection, which augur well for its application in water safety control processes.

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Photoelectrochemical impedance spectroscopy sensor for cloxacillin based on tetrabutylammonium octamolybdate

Cited by 14 publications

References 74 publications

Surface Modification of Thermoplastic Electrodes for Biosensing Applications via Copper-Catalyzed Click Chemistry

Surface Modification of Thermoplastic Electrodes for Biosensing Applications via Copper-Catalyzed Click Chemistry

An Ultrasensitive Glypican‑3 Electrochemical Aptasensor Based on Reduced Graphene Oxide-Carboxymethylchitosan-Hemin/Palladium Nanoparticles

Development of an impedimetric sensor based on carbon dots and chitosan nanocomposite modified electrode for Cu(II) detection in water

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