Photoelectrochemical deoxyribonucleic acid sensing on a nanostructured TiO2 electrode

Abstract

A nanostructured TiO2 electrode chemisorbed with probe deoxyribonucleic acid (DNA) can photoelectrochemically detect a dye-labeled target DNA molecule. After the hybridization between the probe and target DNA molecules, light irradiation generates electrons in the dye molecules, and these electrons are injected into the TiO2 electrode. The resulting photocurrent can be measured and corresponds to the concentration of target DNA. This sensor can quantitatively detect target DNA at lower than nanomolar concentrations. In addition, by utilizing two different dyes, different DNA sequences can be detected on the TiO2 electrode.

Synthesis and phase transformation of TiO2 nano-crystals in aqueous solutions

“…The latter includes medical applications, cosmetics, catalysts, 1) photocatalysts, 2) gas sensors, 3),4) lithium batteries, 5) biomolecular sensors 6) and dye-sensitized solar cells.…”

Imprint Molding of a Microfluidic Optical Cell on Thermoplastics with Reduced Surface Roughness for the Detection of Copper Ions

“…Here, we detected rhodamine B, which is supposed to have a UV-vis absorption peak at 550 nm, [36][37][38] using the microfluidic optical cell imprint-molded on PET. A simple chamber was formed on PET (length, 8 mm; width, 8 mm; depth, 0.5 mm) and bonded with a flat PET via thermal bonding at 60 C under 0.1 MPa for 20 min, assisted by the amine-PDMS linker, 31 which was also used as an anti-adhesion coating material in this study.…”

Nanofabrication of Metal Oxide Patterns Using Self-Assembled Monolayers

“…TiO 2 thin film prepared on a glass would be constructed of not acicular crystals but polycrystals in under layer. 101 Tin oxide have been widely used in gas sensors 102 , optical devices 103 , lithium batteries 104 , bio-sensors 105 , catalyst for chemical reaction(anisole to 2,6-xylenol, etc.) 106 and so on.…”