Photodynamic Therapy with Tolonium Chloride and a Diode Laser (635 nm) in the Non-Surgical Management of Periodontitis: A Clinical Study

Mobadder, Marwan El; Namour, Amaury; Grzech‐Leśniak, Kinga

doi:10.3390/jcm12165270

Cited by 1 publication

(2 citation statements)

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“…Despite the fact that an ADA 2018 consensus report stated that laser therapy has limited benefits [ 33 ], a large number of studies emphasize the better outcome of SRP with laser addition. Minimally invasive laser therapy efficiency is currently widely recognized, showing significant clinical improvement in cases of moderate to advanced periodontal disease [ 9 , 34 , 35 ], its effects being highlighted both in vitro and in vivo on cell lines of fibroblasts mimicking the periodontal tissue, and up to the mitochondrial level [ 36 , 37 ].…”

Section: Discussionmentioning

confidence: 99%

“…The results of this study reveal that adding laser treatment to SRP significantly decreases PPD, in line with the results of other studies. Laser conditioning of the root surface, de-epithelizing the internal and external area of the pocket, and stimulating bone growth by means of laser energy bring an important benefit in improving periodontal health [ 35 , 38 , 39 , 40 , 41 , 42 ].…”

Section: Discussionmentioning

confidence: 99%

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Laser Therapy Effects on Periodontal Status: A Randomized Study Using Gaussian Network Analysis and Structural Equation Modeling Approach

Ciurescu,

Dima,

Ciurescu

et al. 2024

Medicina

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Background and Objectives: This paper aims to assess the role of laser therapy in periodontitis through an innovative approach involving computational prediction and advanced modeling performed through network analysis (Gaussian graphical models—GGMs) and structural equations (SEM). Materials and Methods: Forty patients, exhibiting periodontal pockets with a minimum depth of 5 mm, were randomly divided into two groups: a control group and a laser group. Four specific indicators were measured for each tooth, namely periodontal pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), and plaque index (PI), and the mean of six measured values was recorded at five time markers (baseline, 6 months, 1 year, 2 years, and 4 years). The assessment algorithm included enrollment, measurements, and differential non-surgical periodontal treatment, according to the group allocation. Scaling, root planing, and chlorhexidine 1% were conducted for the control group, and scaling, root planing and erbium, chromium:yttrium-scandium-gallium-garnet (Er,CR:YSGG) laser therapy were conducted for the laser group. Results: The main results highlight that the addition of laser treatment to scaling and root planing led to notable clinical improvements, decreasing the PPD values, reducing the BOP scores, and increasing the CAL. Conclusions: Notable relationships between the specific indicators considered were highlighted by both the GGMs and by SEM, thus confirming their suitability as proxies for the success of periodontal treatment.

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