Photodynamic therapy of eyelid basal cell carcinoma

Kotimäki, Jouko

doi:10.1111/j.1468-3083.2009.03195.x

Cited by 27 publications

(18 citation statements)

References 15 publications

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“…Our literature search regarding the use of PDT in eyelid tumors revealed 75 basal cell carcinoma cases treated with PDT in five studies 79,99,145,198,212 and one case report. 169 In 17 of the 75 patients, no tumor regression was observed (77% response).…”

Section: Accepted Manuscriptmentioning

confidence: 98%

Clinical use of photodynamic therapy in ocular tumors

Çerman

Çekıç

2015

Survey of Ophthalmology

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Section: Accepted Manuscriptmentioning

confidence: 98%

Clinical use of photodynamic therapy in ocular tumors

Çerman

Çekıç

2015

Survey of Ophthalmology

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“…Em oftalmologia há poucos estudos relatados, o uso da TFD com ácido 5-aminolevulínico foi descrita em três estudos e em apenas dois com cloridrato de aminolevulinato de metila. (9)(10)(11)(12)(13)(14) A TFD-MAL é realizada após curetagem da superfície da lesão e MAL por ser mais lipofílico é capaz de penetrar mais profundamente na lesão. Além disso, MAL apresenta seletividade superior ao ALA, poupando as células normais vizinhas, parte dessa ação é justificada por sua captação acelerada pelas células tumorais seja por transporte ativo como passivo.…”

Section: Discussionunclassified

Terapia fotodinâmica em carcinoma basocelular periocular: relato de caso

Carneiro¹,

Macedo²,

Lima³

et al. 2012

Rev. bras.oftalmol.

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“…Preliminary experience suggests promising results without any complications. 29,30 Conjunctival tumours The preliminary results suggest that PDT may be an alternative treatment for ocular surface squamous neoplasia, particularly with diffuse presentation. [31][32][33] Retinal tumours PDT with verteporfin causes fewer side effects as it offers site-specific tumour destruction while sparing surrounding structures.…”

Section: Indications and Resultsmentioning

confidence: 99%

Ocular phototherapy

Singh

2012

Eye

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Phototherapy can be translated to mean 'light or radiant energy-induced treatment.' Lasers have become the exclusive source of light or radiant energy for all applications of phototherapy. Depending on the wavelength, intensity, and duration of exposure, tissues can either absorb the energy (photocoagulation, thermotherapy, and photodynamic therapy (PDT)) or undergo ionization (photodisruption). For phototherapy to be effective, the energy has to be absorbed by tissues or more specifically by naturally occurring pigment (xanthophyll, haemoglobin, and melanin) within them. In tissues or tumours that lack natural pigment, dyes (verteporphin, Visudyne) with narrow absorption spectrum can be injected intravenously that act as focal absorbent of laser energy after they have preferentially localized within the tumour. Ocular phototherapy has broad applications in treatment of ocular tumours. Laser photocoagulation, thermotherapy, and PDT can be delivered with low rates of complications and with ease in the outpatient setting. Review of the current literature suggests excellent results when these treatments are applied for benign tumours, particularly for vascular tumours such as circumscribed choroidal haemangioma. For primary malignant tumours, such as choroidal melanoma, thermotherapy, and PDT do not offer local tumour control rates that are equivalent or higher than those achieved with plaque or proton radiation therapy. However, for secondary malignant tumours (choroidal metastases), thermotherapy and PDT can be applied as a palliative treatment. Greater experience is necessary to fully comprehend risks, comparative benefits, and complication of ocular phototherapy of ocular tumours.

show abstract

Photodynamic therapy of eyelid basal cell carcinoma

Abstract: PDT, although experimental in the eyelid area because of the small amount of data and the lack of a long-term follow-up, may be considered a promising comprehensive alternative when treating BCC in the eyelid area.

Cited by 27 publications

References 15 publications

Clinical use of photodynamic therapy in ocular tumors

Clinical use of photodynamic therapy in ocular tumors

Terapia fotodinâmica em carcinoma basocelular periocular: relato de caso

Ocular phototherapy

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