Photodynamic therapy mediated by nanoparticles Aluminum Chloro Phthalocyanine in oral squamous carcinoma cells

Cangussu, Lílian Mendes Borburema; Souza, Ludmilla Regina de; Souza, Marcela Gonçalves de; Monteiro, Renato Sobral; Muehlmann, Luís Alexandre; Souza, Paulo Narcizo de; Farias, Lucyana Conceição; Santos, Sérgio Henrique Sousa; Paula, Alfredo Maurício Batista de; Guimarães, André Luiz Sena

doi:10.1007/s10103-022-03517-z

Cited by 3 publications

(11 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…23 Moreover, phthalocyanine dyes, including liposome-incorporated 2-(morpholin-4-yl) ethoxy phthalocyanines, Pc4, Pc4 loaded nanoparticles, IRDye700DX, and AlPc-NE, were also applied in the reviewed studies. 32,50,60,63,65 Other PSs such as Graphene quantum dots (GQDs) conjugated to polyethylene glycol (PEG), 53 new series of 1-benzothiazolylphenylbenzotriazoles, 47 porphyrazines, 44 palmatine hydrochloride (PaH), 45 HMnO2-IR780, 42 sulfur-doped carbon dots, 37 and erythrosine 36 were also used. Overall assessment showed slightly better results reported in the third generation and new PSs.…”

Section: Photosensitizermentioning

confidence: 99%

“…Some studies used only one concentration, 33,[38][39][40]43,45,[47][48][49]51,55,56,58,59,66,67 while others evaluated the effect of different concentrations on their cell lines. 9,23,[29][30][31][32]34,36,37,41,42,44,46,50,53,54,57,[60][61][62][63][64][65]68 Most studies showed that the results were dependent on concentrations. 9,23,[29][30][31]34,36,41,42,44,46,…”

Section: Photosensitizermentioning

confidence: 99%

“…9,23,[29][30][31]34,36,41,42,44,46,50,53,54,57,[60][61][62][63]65,68 But in some studies, concentrations were not significant in the results. 32,37,64 The exact concentrations used for each of the specific PSs are stated in Table S1.…”

Section: Photosensitizermentioning

confidence: 99%

“…The most frequent light source was the laser, used in 19 studies (Table S1). 9,23,29,34,37,38,41,42,45,46,49,52,54,[58][59][60]62,64,66 Others included LEDs in 8, 32,40,50,51,57,63,65,69 a UV lamp 30,47,56 in three, and a Tungsten lamp 36,55 and a visible lamp, 30,48 each in two studies.…”

Section: Light Sourcementioning

confidence: 99%

“…The most common range of wavelengths was 600-700 nm used in 26 studies. 9,23,29,[31][32][33][34][35]38,40,41,43,44,46,48,49,52,54,57,60,[63][64][65][66][67]69 Similarly, energy density had a wide range between 0.23 J/cm 2 and 122.58 J/cm 2 . Details are demonstrated in Table S1.…”

Section: Light Sourcementioning

confidence: 99%

See 4 more Smart Citations

In Vitro Anti-tumor Effects of Photodynamic Therapy on Oral Squamous Cell Carcinoma: A Review

et al. 2022

View full text Add to dashboard Cite

Introduction: Due to the increasing prevalence and high mortality rate of oral squamous cell carcinoma (OSCC) and problems with its routine treatments, more recent modalities like photodynamic therapy (PDT) have been developed. PDT effectively destroys tumor cells with minimum side effects. Research on in vitro effects of PDT may be helpful in determining the molecular mechanisms responsible for its effectiveness and can lead to the development of more efficient techniques. The aim of this study was to review the use of PDT in OSCC among in vitro studies. Methods: A literature search for English articles on PDT in OSCC was performed in PubMed, Scopus, Google Scholar, and Web of Science. Data were extracted based on the inclusion/exclusion criteria, which were detailed using the PICO framework: all eligible in vitro studies evaluating the effects of PDT on the viability of OSCC compared to controls without PDT were included. Results: Forty-one out of 567 studies were selected. The tongue was the most common OSCC site, 5-aminolevulinic acid was the most used photosensitizer (PS), cell viability/toxicity and apoptosis were the most evaluated outcomes, and lasers with wavelengths of 600-700 nm were the most common light sources and wavelengths respectively. Conclusion: PDT showed promising effects on reducing the viability of OSCC cells. Cell lines from various sources or even those originating from the same location sometimes responded differently to the same protocol. Considering the favorable results obtained from natural PSs and regarding their additional health-promoting properties, their use in future investigations with different cell lines and light specifications is recommended.

show abstract

Section: Photosensitizermentioning

confidence: 99%

Section: Photosensitizermentioning

confidence: 99%

Section: Photosensitizermentioning

confidence: 99%

Section: Light Sourcementioning

confidence: 99%

Section: Light Sourcementioning

confidence: 99%

See 3 more Smart Citations

In Vitro Anti-tumor Effects of Photodynamic Therapy on Oral Squamous Cell Carcinoma: A Review

et al. 2022

View full text Add to dashboard Cite

show abstract

Unveiling the potential of angiotensin-converting enzyme as a therapeutic target in head and neck squamous carcinoma

Gomes,

de Souza,

da Rocha

et al. 2024

Gene Reports

View full text Add to dashboard Cite

Photodynamic Therapy for Eye, Ear, Laryngeal Area, and Nasal and Oral Cavity Diseases: A Review

Domka,

Bartusik-Aebisher,

Mytych

et al. 2024

Cancers

View full text Add to dashboard Cite

Photodynamic therapy (PDT) has emerged as a promising modality for the treatment of various diseases. This non-invasive approach utilizes photosensitizing agents and light to selectively target and destroy abnormal cells, providing a valuable alternative to traditional treatments. Research studies have explored the application of PDT in different areas of the head. Research is focusing on a growing number of new developments and treatments for cancer. One of these methods is PDT. Photodynamic therapy is now a revolutionary, progressive method of cancer therapy. A very important feature of PDT is that cells cannot become immune to singlet oxygen. With this therapy, patients can avoid lengthy and costly surgeries. PDT therapy is referred to as a safe and highly selective therapy. These studies collectively highlight the potential of PDT as a valuable therapeutic option in treating the head area. As research in this field progresses, PDT may become increasingly integrated into the clinical management of these conditions, offering a balance between effectiveness and minimal invasiveness.

show abstract

Photodynamic therapy mediated by nanoparticles Aluminum Chloro Phthalocyanine in oral squamous carcinoma cells

Cited by 3 publications

References 47 publications

In Vitro Anti-tumor Effects of Photodynamic Therapy on Oral Squamous Cell Carcinoma: A Review

In Vitro Anti-tumor Effects of Photodynamic Therapy on Oral Squamous Cell Carcinoma: A Review

Unveiling the potential of angiotensin-converting enzyme as a therapeutic target in head and neck squamous carcinoma

Photodynamic Therapy for Eye, Ear, Laryngeal Area, and Nasal and Oral Cavity Diseases: A Review

Contact Info

Product

Resources

About