Photodynamic therapy in treatment of severe oral lichen planus

Abstract

The aim of the study was to elaborate the rationale for the application of photodynamic therapy in complex treatment of patient with severe oral lichen planus. Complex clinical and laboratory examination and treatment was performed in 54 patients divided on 3 groups. Diagnosis of oral lichen planus was based on clinical, histological and immunohistochemical features. Group 1 received standard treatment, in the second group photodynamic therapy was conducted in addition to conventional treatment, patients in the third group received only photodynamic therapy. The study results proved photodynamic therapy to be useful tool in complex treatment of severe oral lichen planus.

Application of fractal dimension analysis and photodynamic diagnosis in the case of differentiation between lichen planus and leukoplakia: A preliminary study

“…Photodynamic therapy as a noninvasive procedure is more frequently used for the treatment of leukoplakia and LP. [22][23][24][25][26][27] Maloth et al revealed that in their study, in the leukoplakia group, 17% of cases showed a complete response, 66% showed a partial response and 17% of the lesions did not respond to the treatment. In the LP group, 80% of the lesions showed a partial response and 20% did not respond.…”