1995
DOI: 10.1016/s1078-5884(05)80017-6
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Photodynamic therapy in a cell culture model of human intimal hyperplasia

Abstract: PDT in the appropriate drug and light doses can eliminate human VSMCs, including those responsible for vascular restenosis.

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Cited by 5 publications
(3 citation statements)
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“…In cardiology there are increasing attempts to design a PDT for the treatment of restenosis (Pai et al 2005; Rockson et al 2000; Sobeh et al 1995; Zubilewicz et al 2001). To date, the preferred option of the treatment of post-PCI restenosis has been the use of drug-eluting stents (DESs) delivering antiproliferative agents to the vessel wall.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In cardiology there are increasing attempts to design a PDT for the treatment of restenosis (Pai et al 2005; Rockson et al 2000; Sobeh et al 1995; Zubilewicz et al 2001). To date, the preferred option of the treatment of post-PCI restenosis has been the use of drug-eluting stents (DESs) delivering antiproliferative agents to the vessel wall.…”
Section: Discussionmentioning
confidence: 99%
“…Because intimal hyperplasia consists mainly of proliferating vascular smooth muscle cells (VSMCs), control of their proliferation or their elimination may be a good target in the therapy of restenosis. It is worth mentioning that over 50 agents were shown to modulate intimal hyperplasia and restenosis in animal models favorably, but few have been shown to be effective in humans (Sobeh et al 1995). …”
Section: Introductionmentioning
confidence: 99%
“…The ICG solution was sterilized using a 0.22 μm syringe filter, and stored at 4°C in the dark before use. 24…”
Section: Photosensitizermentioning
confidence: 99%